Artículos

psychedelics as transformative therapeutics / Bryan L. Roth en The American Journal of Psychiatry, Año 2023 - Vol. 180 - No. 5 (Mayo)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2023 - Vol. 180 - No. 5 (Mayo) . - pp. 340-347 Título : psychedelics as transformative therapeutics Tipo de documento: texto impreso Autores: Bryan L. Roth, Autor ; Ryan H. Gumpper, Autor Fecha de publicación: 2023 Artículo en la página: pp. 340-347 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Psicofarmacología, Farmacocinética, Psicodélicos, Drogas alucinógenas Resumen: Over the past decade, psychedelic compounds have emerged as potentially transformative therapeutics for a variety of intractable neuropsychiatric conditions. However, historically most of the basic science has utilized these compounds as probes to interrogate various endogenous neurotransmitter systems—mainly the serotonin 5-HT2A receptor. Link: ./index.php?lvl=notice_display&id=29984 [artículo] psychedelics as transformative therapeutics [texto impreso] / Bryan L. Roth, Autor ; Ryan H. Gumpper, Autor . - 2023 . - pp. 340-347. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2023 - Vol. 180 - No. 5 (Mayo) . - pp. 340-347 Palabras clave: Psicofarmacología, Farmacocinética, Psicodélicos, Drogas alucinógenas Resumen: Over the past decade, psychedelic compounds have emerged as potentially transformative therapeutics for a variety of intractable neuropsychiatric conditions. However, historically most of the basic science has utilized these compounds as probes to interrogate various endogenous neurotransmitter systems—mainly the serotonin 5-HT2A receptor. Link: ./index.php?lvl=notice_display&id=29984

Double-blind placebo-controlled study of memantine in trichotillomania and skin-picking disorder / Jon E. Grant en The American Journal of Psychiatry, Año 2023 - Vol. 180 - No. 5 (Mayo)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2023 - Vol. 180 - No. 5 (Mayo) . - pp. 348-356 Título : Double-blind placebo-controlled study of memantine in trichotillomania and skin-picking disorder Tipo de documento: texto impreso Autores: Jon E. Grant, Autor ; Eve Chesivoir, Autor ; Stephanie Valle, Autor Fecha de publicación: 2023 Artículo en la página: pp. 348-356 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastorno obsesivo-compulsivo (TOC), Farmacoterapia, Psicofarmacología Resumen: Trichotillomania and skin-picking disorder are underrecognized and often disabling conditions in which individuals repeatedly pull at their hair or pick at their skin, leading to noticeable hair loss or tissue damage. To date there is a severe paucity of evidence-based treatments for these conditions. In this study, the authors sought to determine whether memantine, a glutamate modulator, is more effective than placebo in reducing hair-pulling and skin-picking behavior. Link: ./index.php?lvl=notice_display&id=29985 [artículo] Double-blind placebo-controlled study of memantine in trichotillomania and skin-picking disorder [texto impreso] / Jon E. Grant, Autor ; Eve Chesivoir, Autor ; Stephanie Valle, Autor . - 2023 . - pp. 348-356. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2023 - Vol. 180 - No. 5 (Mayo) . - pp. 348-356 Palabras clave: Trastorno obsesivo-compulsivo (TOC), Farmacoterapia, Psicofarmacología Resumen: Trichotillomania and skin-picking disorder are underrecognized and often disabling conditions in which individuals repeatedly pull at their hair or pick at their skin, leading to noticeable hair loss or tissue damage. To date there is a severe paucity of evidence-based treatments for these conditions. In this study, the authors sought to determine whether memantine, a glutamate modulator, is more effective than placebo in reducing hair-pulling and skin-picking behavior. Link: ./index.php?lvl=notice_display&id=29985

Attention bias modification treatment versus a selective serotonin reuptake inhibitor or waiting list control for social anxiety disorder / Gal Arad en The American Journal of Psychiatry, Año 2023 - Vol. 180 - No. 5 (Mayo)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2023 - Vol. 180 - No. 5 (Mayo) . - pp. 357-366 Título : Attention bias modification treatment versus a selective serotonin reuptake inhibitor or waiting list control for social anxiety disorder : a randomized clinical trial Tipo de documento: texto impreso Autores: Gal Arad, Autor ; Omer Azriel, Autor ; Daniel S. Pine, Autor Fecha de publicación: 2023 Artículo en la página: pp. 357-366 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastornos de ansiedad, Trastornos de ansiedad social, Antidepresivos, ISRS Resumen: Social anxiety disorder is common and impairing. The efficacy of pharmacotherapy is moderate, highlighting the need for alternative therapies. This study compared the efficacy of gaze-contingent music reward therapy (GC-MRT), an eye-tracking-based attention bias modification treatment, with a selective serotonin reuptake inhibitor (SSRI) treatment or a waiting list control condition in reducing social anxiety disorder symptoms. Superior clinical effects of similar magnitude were expected for the active treatments relative to the control condition. Link: ./index.php?lvl=notice_display&id=29986 [artículo] Attention bias modification treatment versus a selective serotonin reuptake inhibitor or waiting list control for social anxiety disorder : a randomized clinical trial [texto impreso] / Gal Arad, Autor ; Omer Azriel, Autor ; Daniel S. Pine, Autor . - 2023 . - pp. 357-366. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2023 - Vol. 180 - No. 5 (Mayo) . - pp. 357-366 Palabras clave: Trastornos de ansiedad, Trastornos de ansiedad social, Antidepresivos, ISRS Resumen: Social anxiety disorder is common and impairing. The efficacy of pharmacotherapy is moderate, highlighting the need for alternative therapies. This study compared the efficacy of gaze-contingent music reward therapy (GC-MRT), an eye-tracking-based attention bias modification treatment, with a selective serotonin reuptake inhibitor (SSRI) treatment or a waiting list control condition in reducing social anxiety disorder symptoms. Superior clinical effects of similar magnitude were expected for the active treatments relative to the control condition. Link: ./index.php?lvl=notice_display&id=29986

A novel psychosocial intervention for motivational negative symptoms in schizophrenia / L. Felice Reddy en The American Journal of Psychiatry, Año 2023 - Vol. 180 - No. 5 (Mayo)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2023 - Vol. 180 - No. 5 (Mayo) . - pp. 367-376 Título : A novel psychosocial intervention for motivational negative symptoms in schizophrenia : combined motivational interviewing and cbt Tipo de documento: texto impreso Autores: L. Felice Reddy, Autor ; Shirley M. Glynn, Autor ; Jessica E. McGovern, Autor Fecha de publicación: 2023 Artículo en la página: pp. 367-376 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Psicoterapia, Comportamiento, Espectro de esquizofrenia, trastornos psicóticos Resumen: Negative symptoms are a primary cause of disability in schizophrenia for which there are no established pharmacotherapies. This study evaluated a novel psychosocial intervention that combined two evidence-based practices—motivational interviewing and cognitive-behavioral therapy (MI-CBT)—for the treatment of motivational negative symptoms. Link: ./index.php?lvl=notice_display&id=29987 [artículo] A novel psychosocial intervention for motivational negative symptoms in schizophrenia : combined motivational interviewing and cbt [texto impreso] / L. Felice Reddy, Autor ; Shirley M. Glynn, Autor ; Jessica E. McGovern, Autor . - 2023 . - pp. 367-376. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2023 - Vol. 180 - No. 5 (Mayo) . - pp. 367-376 Palabras clave: Psicoterapia, Comportamiento, Espectro de esquizofrenia, trastornos psicóticos Resumen: Negative symptoms are a primary cause of disability in schizophrenia for which there are no established pharmacotherapies. This study evaluated a novel psychosocial intervention that combined two evidence-based practices—motivational interviewing and cognitive-behavioral therapy (MI-CBT)—for the treatment of motivational negative symptoms. Link: ./index.php?lvl=notice_display&id=29987

Safety of antipsychotic polypharmacy versus monotherapy in a nationwide cohort of 61,889 patients with schizophrenia / Heidi T. Taipale en The American Journal of Psychiatry, Año 2023 - Vol. 180 - No. 5 (Mayo)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2023 - Vol. 180 - No. 5 (Mayo) . - pp. 377-385 Título : Safety of antipsychotic polypharmacy versus monotherapy in a nationwide cohort of 61,889 patients with schizophrenia Tipo de documento: texto impreso Autores: Heidi T. Taipale, Autor ; Antti J. Tanskanen, Autor ; Jari Tiihonen, Autor Fecha de publicación: 2023 Artículo en la página: pp. 377-385 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Polifarmacia, Espectro de esquizofrenia, Trastornos psicóticos Resumen: The authors sought to study the safety of antipsychotic polypharmacy compared with monotherapy in specific dosage categories. Patients with schizophrenia (N=61,889; median follow-up, 14.8 years [IQR=7.4–22.0]) were identified from the Finnish nationwide inpatient care register and followed up over the period 1996–2017. Link: ./index.php?lvl=notice_display&id=29988 [artículo] Safety of antipsychotic polypharmacy versus monotherapy in a nationwide cohort of 61,889 patients with schizophrenia [texto impreso] / Heidi T. Taipale, Autor ; Antti J. Tanskanen, Autor ; Jari Tiihonen, Autor . - 2023 . - pp. 377-385. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2023 - Vol. 180 - No. 5 (Mayo) . - pp. 377-385 Palabras clave: Antipsicóticos, Polifarmacia, Espectro de esquizofrenia, Trastornos psicóticos Resumen: The authors sought to study the safety of antipsychotic polypharmacy compared with monotherapy in specific dosage categories. Patients with schizophrenia (N=61,889; median follow-up, 14.8 years [IQR=7.4–22.0]) were identified from the Finnish nationwide inpatient care register and followed up over the period 1996–2017. Link: ./index.php?lvl=notice_display&id=29988

Risk of experiencing an overdose event for patients undergoing treatment with medication for opioid use disorder / Laura Brandt en The American Journal of Psychiatry, Año 2023 - Vol. 180 - No. 5 (Mayo)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2023 - Vol. 180 - No. 5 (Mayo) . - pp. 386-394 Título : Risk of experiencing an overdose event for patients undergoing treatment with medication for opioid use disorder Tipo de documento: texto impreso Autores: Laura Brandt, Autor ; Mei-Chen Hu, Autor ; Ying Liu, Autor Fecha de publicación: 2023 Artículo en la página: pp. 386-394 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastornos adictivos relacionados con sustancias, Opioides, Tratamiento Asistido por Medicamentos, Psiquiatría de Adicciones Resumen: Overdose risk during a course of treatment with medication for opioid use disorder (MOUD) has not been clearly delineated. The authors sought to address this gap by leveraging a new data set from three large pragmatic clinical trials of MOUD. Link: ./index.php?lvl=notice_display&id=29989 [artículo] Risk of experiencing an overdose event for patients undergoing treatment with medication for opioid use disorder [texto impreso] / Laura Brandt, Autor ; Mei-Chen Hu, Autor ; Ying Liu, Autor . - 2023 . - pp. 386-394. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2023 - Vol. 180 - No. 5 (Mayo) . - pp. 386-394 Palabras clave: Trastornos adictivos relacionados con sustancias, Opioides, Tratamiento Asistido por Medicamentos, Psiquiatría de Adicciones Resumen: Overdose risk during a course of treatment with medication for opioid use disorder (MOUD) has not been clearly delineated. The authors sought to address this gap by leveraging a new data set from three large pragmatic clinical trials of MOUD. Link: ./index.php?lvl=notice_display&id=29989