Artículos

Olanzapine versus aripiprazole for the treatment of agitation in acutely ill patients with schizophrenia / Bruce J. Kinon en Journal of Clinical Psychopharmacology, Año 2008 - Vol. 28 - No. 6 (Diciembre)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 601-607 Título : Olanzapine versus aripiprazole for the treatment of agitation in acutely ill patients with schizophrenia Tipo de documento: texto impreso Autores: Bruce J. Kinon, Autor ; Virginia L. Stauffer, Autor Fecha de publicación: 2023 Artículo en la página: pp. 601-607 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Enfermedad aguda, Agentes antipsicóticos, Benzodiazepinas, Glucosa en sangre/efectos por medicamentos, Hospitalización, Lorazepam, Olanzapina, Piperazinas, Agitación psicomotora, Agitación psicomotora, Esquizofrenia. Resumen: Rapid control of agitation is of critical importance in the treatment of acutely ill patients with schizophrenia. Both olanzapine and aripiprazole have been shown to be safe and effective in this setting, with each having somewhat different receptor binding affinity profiles. Link: ./index.php?lvl=notice_display&id=30817 [artículo] Olanzapine versus aripiprazole for the treatment of agitation in acutely ill patients with schizophrenia [texto impreso] / Bruce J. Kinon, Autor ; Virginia L. Stauffer, Autor . - 2023 . - pp. 601-607. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 601-607 Palabras clave: Enfermedad aguda, Agentes antipsicóticos, Benzodiazepinas, Glucosa en sangre/efectos por medicamentos, Hospitalización, Lorazepam, Olanzapina, Piperazinas, Agitación psicomotora, Agitación psicomotora, Esquizofrenia. Resumen: Rapid control of agitation is of critical importance in the treatment of acutely ill patients with schizophrenia. Both olanzapine and aripiprazole have been shown to be safe and effective in this setting, with each having somewhat different receptor binding affinity profiles. Link: ./index.php?lvl=notice_display&id=30817

Striatal and extrastriatal d2/d3-receptor-binding properties of ziprasidone / Ingo B. Vernaleken en Journal of Clinical Psychopharmacology, Año 2008 - Vol. 28 - No. 6 (Diciembre)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 608-617 Título : Striatal and extrastriatal d2/d3-receptor-binding properties of ziprasidone : A positron emission tomography study with [18F]fallypride and [11C]raclopride (D2/D3-receptor occupancy of ziprasidone) Tipo de documento: texto impreso Autores: Ingo B. Vernaleken, Autor ; Christine Fellows, Autor ; Hildegard Janouschek, Autor Fecha de publicación: 2023 Artículo en la página: pp. 608-617 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Agentes antipsicóticos, Relación Dosis-Respuesta, Piperazinas, Radiofármacos, Receptores de Dopamina D2, Esquizofrenia. Resumen: To elucidate the "atypicality" of ziprasidone, its striatal and extrastriatal D2/D3-receptor binding was characterized in patients with schizophrenia under steady-state conditions. These data were compared with striatal receptor occupancy values after single-dose ziprasidone ingestion in healthy controls. [18F]fallypride positron emission tomography (PET) recordings were obtained in 15 patients under steady-state ziprasidone treatment at varying time points after the last dose. Link: ./index.php?lvl=notice_display&id=30818 [artículo] Striatal and extrastriatal d2/d3-receptor-binding properties of ziprasidone : A positron emission tomography study with [18F]fallypride and [11C]raclopride (D2/D3-receptor occupancy of ziprasidone) [texto impreso] / Ingo B. Vernaleken, Autor ; Christine Fellows, Autor ; Hildegard Janouschek, Autor . - 2023 . - pp. 608-617. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 608-617 Palabras clave: Agentes antipsicóticos, Relación Dosis-Respuesta, Piperazinas, Radiofármacos, Receptores de Dopamina D2, Esquizofrenia. Resumen: To elucidate the "atypicality" of ziprasidone, its striatal and extrastriatal D2/D3-receptor binding was characterized in patients with schizophrenia under steady-state conditions. These data were compared with striatal receptor occupancy values after single-dose ziprasidone ingestion in healthy controls. [18F]fallypride positron emission tomography (PET) recordings were obtained in 15 patients under steady-state ziprasidone treatment at varying time points after the last dose. Link: ./index.php?lvl=notice_display&id=30818

A 2-year prospective follow-up study of lower urinary tract symptoms in patients treated with clozapine / Seong Hoon Jeong en Journal of Clinical Psychopharmacology, Año 2008 - Vol. 28 - No. 6 (Diciembre)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 618-624 Título : A 2-year prospective follow-up study of lower urinary tract symptoms in patients treated with clozapine Tipo de documento: texto impreso Autores: Seong Hoon Jeong, Autor ; Jong Hhoon Kim, Autor ; Yong Min Ahn, Autor Fecha de publicación: 2023 Artículo en la página: pp. 618-624 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Clozapina, Calidad de vida, Estrés psicológico, Incontinencia urinaria, Trastornos de la micción - psicología Resumen: Urinary incontinence and enuresis are well-known side effects of clozapine. However, clinical experience has shown that patients also suffer from diverse lower urinary tract symptoms (LUTS). The natural course of clozapine-related LUTS is unclear. Thus, a longitudinal follow-up study is needed. A total of 101 subjects who were taking clozapine initially participated. Link: ./index.php?lvl=notice_display&id=30819 [artículo] A 2-year prospective follow-up study of lower urinary tract symptoms in patients treated with clozapine [texto impreso] / Seong Hoon Jeong, Autor ; Jong Hhoon Kim, Autor ; Yong Min Ahn, Autor . - 2023 . - pp. 618-624. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 618-624 Palabras clave: Clozapina, Calidad de vida, Estrés psicológico, Incontinencia urinaria, Trastornos de la micción - psicología Resumen: Urinary incontinence and enuresis are well-known side effects of clozapine. However, clinical experience has shown that patients also suffer from diverse lower urinary tract symptoms (LUTS). The natural course of clozapine-related LUTS is unclear. Thus, a longitudinal follow-up study is needed. A total of 101 subjects who were taking clozapine initially participated. Link: ./index.php?lvl=notice_display&id=30819

Predictors for starting depot administration of risperidone in chronic users of antipsychotics / Jelle Vehof en Journal of Clinical Psychopharmacology, Año 2008 - Vol. 28 - No. 6 (Diciembre)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 625-630 Título : Predictors for starting depot administration of risperidone in chronic users of antipsychotics Tipo de documento: texto impreso Autores: Jelle Vehof, Autor ; Maarten J. Postma, Autor ; Richard Bruggeman, Autor Fecha de publicación: 2023 Artículo en la página: pp. 625-630 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Agentes antipsicóticos, Enfermedades de los ganglios basales, Antagonistas colinérgicos, Enfermedad crónica, Servicios de Farmacia Comunitaria, Inyecciones, Adherencia a la medicación, Risperidona, Esquizofrenia. Resumen: Risperidone long-acting injectable (RLAI), the first second-generation depot antipsychotic, has extensively been studied before introduction. Thereafter, questions about the type of patients actually treated with RLAI in daily practice remain to be answered for making valid antipsychotic treatment comparisons involving RLAI in observational studies. Link: ./index.php?lvl=notice_display&id=30820 [artículo] Predictors for starting depot administration of risperidone in chronic users of antipsychotics [texto impreso] / Jelle Vehof, Autor ; Maarten J. Postma, Autor ; Richard Bruggeman, Autor . - 2023 . - pp. 625-630. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 625-630 Palabras clave: Agentes antipsicóticos, Enfermedades de los ganglios basales, Antagonistas colinérgicos, Enfermedad crónica, Servicios de Farmacia Comunitaria, Inyecciones, Adherencia a la medicación, Risperidona, Esquizofrenia. Resumen: Risperidone long-acting injectable (RLAI), the first second-generation depot antipsychotic, has extensively been studied before introduction. Thereafter, questions about the type of patients actually treated with RLAI in daily practice remain to be answered for making valid antipsychotic treatment comparisons involving RLAI in observational studies. Link: ./index.php?lvl=notice_display&id=30820

An innovative design to establish proof of concept of the antidepressant effects of the nr2b subunit selective n-methyl-d-aspartate antagonist, cp-101,606, in patients with treatment-refractory major depressive disorder / Sheldon H. Preskorn en Journal of Clinical Psychopharmacology, Año 2008 - Vol. 28 - No. 6 (Diciembre)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 631-637 Título : An innovative design to establish proof of concept of the antidepressant effects of the nr2b subunit selective n-methyl-d-aspartate antagonist, cp-101,606, in patients with treatment-refractory major depressive disorder Tipo de documento: texto impreso Autores: Sheldon H. Preskorn, Autor ; Bryan Baker, Autor ; Sheela Kolluri, Autor Fecha de publicación: 2023 Artículo en la página: pp. 631-637 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Agentes antidepresivos, Trastorno depresivo mayor, Resistencia a las drogas, Antagonistas de aminoácidos excitadores, Paroxetina, Piperidinas, Inhibidores selectivos de la recaptación de serotonina, Índice de gravedad de la enfermedad. Resumen: This randomized, placebo-controlled, double-blind study was the first to evaluate the antidepressant efficacy, safety, and tolerability of an NR2B subunit-selective N-methyl-D-aspartate receptor antagonist, CP-101,606. Subjects had major depression, according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria and a history of treatment refractoriness to least 1 adequate trial of a selective serotonin reuptake inhibitor. Link: ./index.php?lvl=notice_display&id=30821 [artículo] An innovative design to establish proof of concept of the antidepressant effects of the nr2b subunit selective n-methyl-d-aspartate antagonist, cp-101,606, in patients with treatment-refractory major depressive disorder [texto impreso] / Sheldon H. Preskorn, Autor ; Bryan Baker, Autor ; Sheela Kolluri, Autor . - 2023 . - pp. 631-637. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 631-637 Palabras clave: Agentes antidepresivos, Trastorno depresivo mayor, Resistencia a las drogas, Antagonistas de aminoácidos excitadores, Paroxetina, Piperidinas, Inhibidores selectivos de la recaptación de serotonina, Índice de gravedad de la enfermedad. Resumen: This randomized, placebo-controlled, double-blind study was the first to evaluate the antidepressant efficacy, safety, and tolerability of an NR2B subunit-selective N-methyl-D-aspartate receptor antagonist, CP-101,606. Subjects had major depression, according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria and a history of treatment refractoriness to least 1 adequate trial of a selective serotonin reuptake inhibitor. Link: ./index.php?lvl=notice_display&id=30821

A double-masked, placebo-controlled study of fluoxetine for hypochondriasis / Brian A. Fallon en Journal of Clinical Psychopharmacology, Año 2008 - Vol. 28 - No. 6 (Diciembre)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 638-645 Título : A double-masked, placebo-controlled study of fluoxetine for hypochondriasis Tipo de documento: texto impreso Autores: Brian A. Fallon, Autor ; Eva Petkova, Autor ; Natalia Skritskaya, Autor Fecha de publicación: 2023 Artículo en la página: pp. 638-645 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Envejecimiento, Connecticut, Fluoxetina - efectos adversos, Hipocondría - psicología, Abandonos de pacientes, Inhibidores selectivos de la recaptación de serotonina. Resumen: This study assessed the efficacy, durability, and tolerability of fluoxetine for hypochondriasis, a disorder for which controlled pharmacological trials are scarce. Fifty-seven patients with hypochondriasis were enrolled: 12 discontinued during the placebo run-in, and 45 were randomized to either fluoxetine or placebo for 12 weeks (acute treatment). Responder status was defined as a Clinical Global Impression rating for hypochondriasis of much or very much improved. Link: ./index.php?lvl=notice_display&id=30822 [artículo] A double-masked, placebo-controlled study of fluoxetine for hypochondriasis [texto impreso] / Brian A. Fallon, Autor ; Eva Petkova, Autor ; Natalia Skritskaya, Autor . - 2023 . - pp. 638-645. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 638-645 Palabras clave: Envejecimiento, Connecticut, Fluoxetina - efectos adversos, Hipocondría - psicología, Abandonos de pacientes, Inhibidores selectivos de la recaptación de serotonina. Resumen: This study assessed the efficacy, durability, and tolerability of fluoxetine for hypochondriasis, a disorder for which controlled pharmacological trials are scarce. Fifty-seven patients with hypochondriasis were enrolled: 12 discontinued during the placebo run-in, and 45 were randomized to either fluoxetine or placebo for 12 weeks (acute treatment). Responder status was defined as a Clinical Global Impression rating for hypochondriasis of much or very much improved. Link: ./index.php?lvl=notice_display&id=30822

Pharmacokinetics of sertraline across pregnancy and postpartum / Marlene P. Freeman en Journal of Clinical Psychopharmacology, Año 2008 - Vol. 28 - No. 6 (Diciembre)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 646-653 Título : Pharmacokinetics of sertraline across pregnancy and postpartum Tipo de documento: texto impreso Autores: Marlene P. Freeman, Autor ; Paul E. Nolan, Autor ; Melinda F. Davis, Autor Fecha de publicación: 2023 Artículo en la página: pp. 646-653 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: 1-Naftilamina, Trastorno depresivo mayor, Período posparto, Embarazo - complicaciones, Inhibidores selectivos de la recaptación de serotonina, Sertralina Resumen: Insufficient data inform dosing of antidepressants and clinical monitoring for Major Depressive Disorder (MDD) during the perinatal period. The objectives were to assess the pharmacokinetics of sertraline (SER) across pregnancy and postpartum. Participants treated with SER for MDD underwent serial sampling to measure steady-state concentrations of SER and norsertraline during the second and third trimesters and postpartum (total of 3 assessments). Link: ./index.php?lvl=notice_display&id=30823 [artículo] Pharmacokinetics of sertraline across pregnancy and postpartum [texto impreso] / Marlene P. Freeman, Autor ; Paul E. Nolan, Autor ; Melinda F. Davis, Autor . - 2023 . - pp. 646-653. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 646-653 Palabras clave: 1-Naftilamina, Trastorno depresivo mayor, Período posparto, Embarazo - complicaciones, Inhibidores selectivos de la recaptación de serotonina, Sertralina Resumen: Insufficient data inform dosing of antidepressants and clinical monitoring for Major Depressive Disorder (MDD) during the perinatal period. The objectives were to assess the pharmacokinetics of sertraline (SER) across pregnancy and postpartum. Participants treated with SER for MDD underwent serial sampling to measure steady-state concentrations of SER and norsertraline during the second and third trimesters and postpartum (total of 3 assessments). Link: ./index.php?lvl=notice_display&id=30823

Drugs with anticholinergic properties as a risk factor for cognitive impairment in elderly people A population-based study / Iacopo Cancelli en Journal of Clinical Psychopharmacology, Año 2008 - Vol. 28 - No. 6 (Diciembre)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 654-659 Título : Drugs with anticholinergic properties as a risk factor for cognitive impairment in elderly people A population-based study Tipo de documento: texto impreso Autores: Iacopo Cancelli, Autor ; Gian Luigi Gigli, Autor ; Antonella Piani, Autor Fecha de publicación: 2023 Artículo en la página: pp. 654-659 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antagonistas colinérgicos, Cognición - efectos de medicamentos, Trastornos cognitivos Resumen: Prevention of drug-related problems is a key issue in the aged. Anticholinergic (ACH) drugs are a biologically plausible and potentially modifiable risk factor for cognitive impairment. Therefore, we intended to evaluate the association between ACH drugs and cognitive impairment. Our study comprised 750 subjects aged 65 years or older. Cognitive impairment was evaluated using Mini-Mental State Examination and Global Deterioration Scale. Link: ./index.php?lvl=notice_display&id=30824 [artículo] Drugs with anticholinergic properties as a risk factor for cognitive impairment in elderly people A population-based study [texto impreso] / Iacopo Cancelli, Autor ; Gian Luigi Gigli, Autor ; Antonella Piani, Autor . - 2023 . - pp. 654-659. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 654-659 Palabras clave: Antagonistas colinérgicos, Cognición - efectos de medicamentos, Trastornos cognitivos Resumen: Prevention of drug-related problems is a key issue in the aged. Anticholinergic (ACH) drugs are a biologically plausible and potentially modifiable risk factor for cognitive impairment. Therefore, we intended to evaluate the association between ACH drugs and cognitive impairment. Our study comprised 750 subjects aged 65 years or older. Cognitive impairment was evaluated using Mini-Mental State Examination and Global Deterioration Scale. Link: ./index.php?lvl=notice_display&id=30824

A controlled trial of bupropion added to nicotine patch and behavioral therapy for smoking cessation in adults with unipolar depressive disorders / A. Eden Evins en Journal of Clinical Psychopharmacology, Año 2008 - Vol. 28 - No. 6 (Diciembre)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 660-666 Título : A controlled trial of bupropion added to nicotine patch and behavioral therapy for smoking cessation in adults with unipolar depressive disorders Tipo de documento: texto impreso Autores: A. Eden Evins, Autor ; Melissa A. Culhane, Autor ; Jonathan E. Alpert, Autor Fecha de publicación: 2023 Artículo en la página: pp. 660-666 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Bupropión, Terapia de modalidad combinada, Trastorno depresivo, Nicotina, Agonistas nicotínicos, Abandonos de pacientes, Tabaquismo, Dejar de fumar - métodos, Tabaquismo - Prevención, Trastorno por consumo de tabaco. Resumen: Although there is a strong relationship between depression and smoking, most nicotine dependence treatment trials exclude depressed smokers. Our objective was to determine whether bupropion improves abstinence rates and abstinence-associated depressive symptoms when added to transdermal nicotine replacement therapy (NRT) and group cognitive behavioral therapy (CBT) in smokers with unipolar depressive disorder (UDD). Link: ./index.php?lvl=notice_display&id=30825 [artículo] A controlled trial of bupropion added to nicotine patch and behavioral therapy for smoking cessation in adults with unipolar depressive disorders [texto impreso] / A. Eden Evins, Autor ; Melissa A. Culhane, Autor ; Jonathan E. Alpert, Autor . - 2023 . - pp. 660-666. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 660-666 Palabras clave: Bupropión, Terapia de modalidad combinada, Trastorno depresivo, Nicotina, Agonistas nicotínicos, Abandonos de pacientes, Tabaquismo, Dejar de fumar - métodos, Tabaquismo - Prevención, Trastorno por consumo de tabaco. Resumen: Although there is a strong relationship between depression and smoking, most nicotine dependence treatment trials exclude depressed smokers. Our objective was to determine whether bupropion improves abstinence rates and abstinence-associated depressive symptoms when added to transdermal nicotine replacement therapy (NRT) and group cognitive behavioral therapy (CBT) in smokers with unipolar depressive disorder (UDD). Link: ./index.php?lvl=notice_display&id=30825

Efficacy of a nicotine (4 mg)-containing lozenge on the cognitive impairment of nicotine withdrawal / Giuseppe Atzori en Journal of Clinical Psychopharmacology, Año 2008 - Vol. 28 - No. 6 (Diciembre)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 667-674 Título : Efficacy of a nicotine (4 mg)-containing lozenge on the cognitive impairment of nicotine withdrawal Tipo de documento: texto impreso Autores: Giuseppe Atzori, Autor ; Charlotte A. Lemmonds, Autor ; Mitchell L. Kotler, Autor Fecha de publicación: 2023 Artículo en la página: pp. 667-674 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Afecto, Cognición, Memoria - efectos de medicamentos, Nicotina, Agonistas nicotínicos, Rendimiento psicomotor, Tabaquismo, Prevención del tabaquismo, Síndrome de abstinencia de sustancias, Trastorno por consumo de tabaco. Resumen: Controversy exists over the effect of tobacco deprivation in nicotine-dependent individuals and the efficacy of nicotine in reversing performance decrements. This study's aim was to assess the efficacy of nicotine (4-mg lozenge) versus placebo on aspects of cognitive and psychomotor performance, mood, and withdrawal symptoms in male and female established smokers. Link: ./index.php?lvl=notice_display&id=30826 [artículo] Efficacy of a nicotine (4 mg)-containing lozenge on the cognitive impairment of nicotine withdrawal [texto impreso] / Giuseppe Atzori, Autor ; Charlotte A. Lemmonds, Autor ; Mitchell L. Kotler, Autor . - 2023 . - pp. 667-674. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 667-674 Palabras clave: Afecto, Cognición, Memoria - efectos de medicamentos, Nicotina, Agonistas nicotínicos, Rendimiento psicomotor, Tabaquismo, Prevención del tabaquismo, Síndrome de abstinencia de sustancias, Trastorno por consumo de tabaco. Resumen: Controversy exists over the effect of tobacco deprivation in nicotine-dependent individuals and the efficacy of nicotine in reversing performance decrements. This study's aim was to assess the efficacy of nicotine (4-mg lozenge) versus placebo on aspects of cognitive and psychomotor performance, mood, and withdrawal symptoms in male and female established smokers. Link: ./index.php?lvl=notice_display&id=30826

Comparison of peripheral and central effects of single and repeated oral dose administrations of bilastine, a new h1 antihistamine / Consuelo García Gea en Journal of Clinical Psychopharmacology, Año 2008 - Vol. 28 - No. 6 (Diciembre)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 675-685 Título : Comparison of peripheral and central effects of single and repeated oral dose administrations of bilastine, a new h1 antihistamine : A dose-range study in healthy volunteers with hydroxyzine and placebo as control treatments Tipo de documento: texto impreso Autores: Consuelo García Gea, Autor ; Joan Martínez Colomer, Autor ; Rosa Antonijoan, Autor Fecha de publicación: 2023 Artículo en la página: pp. 675-685 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Afecto, Atención, Bencimidazoles, Dermatitis, Relación Dosis-Respuesta, Histamina, Hidroxizina, Piperidinas, Rendimiento psicomotor. Resumen: Peripheral anti-H1 and central nervous system (CNS) activities after single (day 1) and repeated (day 7) administrations of increasing doses of bilastine (BIL) were assessed in 20 healthy volunteers throughout a crossover, randomized, double-blind, placebo (PLA)-controlled study. Repeated doses of BIL 20, 40, or 80 mg and hydroxyzine 25 mg (HYD) as positive standard were administered on 7 consecutive days. Link: ./index.php?lvl=notice_display&id=30827 [artículo] Comparison of peripheral and central effects of single and repeated oral dose administrations of bilastine, a new h1 antihistamine : A dose-range study in healthy volunteers with hydroxyzine and placebo as control treatments [texto impreso] / Consuelo García Gea, Autor ; Joan Martínez Colomer, Autor ; Rosa Antonijoan, Autor . - 2023 . - pp. 675-685. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 675-685 Palabras clave: Afecto, Atención, Bencimidazoles, Dermatitis, Relación Dosis-Respuesta, Histamina, Hidroxizina, Piperidinas, Rendimiento psicomotor. Resumen: Peripheral anti-H1 and central nervous system (CNS) activities after single (day 1) and repeated (day 7) administrations of increasing doses of bilastine (BIL) were assessed in 20 healthy volunteers throughout a crossover, randomized, double-blind, placebo (PLA)-controlled study. Repeated doses of BIL 20, 40, or 80 mg and hydroxyzine 25 mg (HYD) as positive standard were administered on 7 consecutive days. Link: ./index.php?lvl=notice_display&id=30827