Artículos

A randomized, multicenter, double-blind, placebo-controlled study of the efficacy and safety of aripiprazole for the treatment of alcohol dependence / Raymond F. Anton en Journal of Clinical Psychopharmacology, Año 2008 - Vol. 28 - No. 1 (Febrero)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 1 (Febrero) . - pp. 5-12 Título : A randomized, multicenter, double-blind, placebo-controlled study of the efficacy and safety of aripiprazole for the treatment of alcohol dependence Tipo de documento: texto impreso Autores: Raymond F. Anton, Autor ; Henry R. Kranzler, Autor ; Christopher Breder, Autor Fecha de publicación: 2023 Artículo en la página: pp. 5-12 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Alcoholismo, Antipsicóticos, Piperazinas, Quinolonas. Resumen: The purpose of this study was to compare the efficacy and safety of aripiprazole with placebo in the treatment of alcoholics. In this 12-week multicenter, double-blind study, 295 patients with Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition alcohol dependence were randomized to treatment with aripiprazole (initiated at 2 mg/d, titrated to a maximum dose of 30mg/d at day 28) or placebo after screening, wherein patients maintained alcohol abstinence for 3 days or more. Link: ./index.php?lvl=notice_display&id=30866 [artículo] A randomized, multicenter, double-blind, placebo-controlled study of the efficacy and safety of aripiprazole for the treatment of alcohol dependence [texto impreso] / Raymond F. Anton, Autor ; Henry R. Kranzler, Autor ; Christopher Breder, Autor . - 2023 . - pp. 5-12. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 1 (Febrero) . - pp. 5-12 Palabras clave: Alcoholismo, Antipsicóticos, Piperazinas, Quinolonas. Resumen: The purpose of this study was to compare the efficacy and safety of aripiprazole with placebo in the treatment of alcoholics. In this 12-week multicenter, double-blind study, 295 patients with Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition alcohol dependence were randomized to treatment with aripiprazole (initiated at 2 mg/d, titrated to a maximum dose of 30mg/d at day 28) or placebo after screening, wherein patients maintained alcohol abstinence for 3 days or more. Link: ./index.php?lvl=notice_display&id=30866

Aripiprazole monotherapy in nonpsychotic bipolar i depression / Michael E. Thase en Journal of Clinical Psychopharmacology, Año 2008 - Vol. 28 - No. 1 (Febrero)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 1 (Febrero) . - pp. 13-20 Título : Aripiprazole monotherapy in nonpsychotic bipolar i depression : Results of 2 randomized, placebo-controlled studies Tipo de documento: texto impreso Autores: Michael E. Thase, Autor ; Alan Jonas, Autor ; Arif Khan, Autor Fecha de publicación: 2023 Artículo en la página: pp. 13-20 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Trastorno bipolar, Trastorno depresivo mayor, Determinación del criterio de valoración, Piperazinas, Quinolonas. Resumen: Although most treatment research on bipolar disorder has focused on mania, depressive episodes occur more frequently among patients with bipolar disorder. Here, we report the results of 2 identically designed, 8-week, multicenter, randomized, double-blind, placebo-controlled studies (CN138-096 and CN138-146) to evaluate the efficacy and safety of aripiprazole monotherapy in outpatients with bipolar I disorder experiencing a major depressive episode without psychotic features. Link: ./index.php?lvl=notice_display&id=30867 [artículo] Aripiprazole monotherapy in nonpsychotic bipolar i depression : Results of 2 randomized, placebo-controlled studies [texto impreso] / Michael E. Thase, Autor ; Alan Jonas, Autor ; Arif Khan, Autor . - 2023 . - pp. 13-20. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 1 (Febrero) . - pp. 13-20 Palabras clave: Antipsicóticos, Trastorno bipolar, Trastorno depresivo mayor, Determinación del criterio de valoración, Piperazinas, Quinolonas. Resumen: Although most treatment research on bipolar disorder has focused on mania, depressive episodes occur more frequently among patients with bipolar disorder. Here, we report the results of 2 identically designed, 8-week, multicenter, randomized, double-blind, placebo-controlled studies (CN138-096 and CN138-146) to evaluate the efficacy and safety of aripiprazole monotherapy in outpatients with bipolar I disorder experiencing a major depressive episode without psychotic features. Link: ./index.php?lvl=notice_display&id=30867

A comparison of the effects of olanzapine and risperidone versus placebo on ghrelin plasma levels / James L. Roerig en Journal of Clinical Psychopharmacology, Año 2008 - Vol. 28 - No. 1 (Febrero)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 1 (Febrero) . - pp. 21-26 Título : A comparison of the effects of olanzapine and risperidone versus placebo on ghrelin plasma levels Tipo de documento: texto impreso Autores: James L. Roerig, Autor ; Kristine J. Steffen, Autor ; James E. Mitchell, Autor Fecha de publicación: 2023 Artículo en la página: pp. 21-26 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Benzodiazepinas, Comportamiento alimentario, Risperidona Resumen: To thoroughly investigate the phenomenon of atypical antipsychotic-associated weight gain, a feeding laboratory paradigm was developed that included obtaining plasma levels of the orexigenic peptide ghrelin that is associated with appetite and eating. This study is a randomized, double-blind, parallel group trial comparing the effects of a 2-week exposure to olanzapine, risperidone, or placebo on plasma ghrelin area under the plasma-time curve (AUC) in 28 healthy human subjects. Subjects were randomized to receive olanzapine, risperidone, or placebo and titrated over 4 days to 10 mg/d or 4 mg/d, respectively. Link: ./index.php?lvl=notice_display&id=30868 [artículo] A comparison of the effects of olanzapine and risperidone versus placebo on ghrelin plasma levels [texto impreso] / James L. Roerig, Autor ; Kristine J. Steffen, Autor ; James E. Mitchell, Autor . - 2023 . - pp. 21-26. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 1 (Febrero) . - pp. 21-26 Palabras clave: Antipsicóticos, Benzodiazepinas, Comportamiento alimentario, Risperidona Resumen: To thoroughly investigate the phenomenon of atypical antipsychotic-associated weight gain, a feeding laboratory paradigm was developed that included obtaining plasma levels of the orexigenic peptide ghrelin that is associated with appetite and eating. This study is a randomized, double-blind, parallel group trial comparing the effects of a 2-week exposure to olanzapine, risperidone, or placebo on plasma ghrelin area under the plasma-time curve (AUC) in 28 healthy human subjects. Subjects were randomized to receive olanzapine, risperidone, or placebo and titrated over 4 days to 10 mg/d or 4 mg/d, respectively. Link: ./index.php?lvl=notice_display&id=30868

Predictors of antipsychotic-induced weight gain in first-episode psychosis Conclusions from a randomized, double-blind, controlled prospective study of olanzapine, risperidone, and haloperidol / Sahoo Saddichha en Journal of Clinical Psychopharmacology, Año 2008 - Vol. 28 - No. 1 (Febrero)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 1 (Febrero) . - pp. 27-31 Título : Predictors of antipsychotic-induced weight gain in first-episode psychosis Conclusions from a randomized, double-blind, controlled prospective study of olanzapine, risperidone, and haloperidol Tipo de documento: texto impreso Autores: Sahoo Saddichha, Autor ; Shahul Ameen, Autor ; Sayeed Akhtar, Autor Fecha de publicación: 2023 Artículo en la página: pp. 27-31 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Benzodiacepinas, Índice de masa corporal, Haloperidol, Olanzapina, Risperidona, Esquizofrenia. Resumen: Antipsychotic-induced weight gain is one of the most distressing adverse effects being observed in recent times. Most studies have been limited by several confounders. Link: ./index.php?lvl=notice_display&id=30869 [artículo] Predictors of antipsychotic-induced weight gain in first-episode psychosis Conclusions from a randomized, double-blind, controlled prospective study of olanzapine, risperidone, and haloperidol [texto impreso] / Sahoo Saddichha, Autor ; Shahul Ameen, Autor ; Sayeed Akhtar, Autor . - 2023 . - pp. 27-31. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 1 (Febrero) . - pp. 27-31 Palabras clave: Antipsicóticos, Benzodiacepinas, Índice de masa corporal, Haloperidol, Olanzapina, Risperidona, Esquizofrenia. Resumen: Antipsychotic-induced weight gain is one of the most distressing adverse effects being observed in recent times. Most studies have been limited by several confounders. Link: ./index.php?lvl=notice_display&id=30869

Safety and tolerability of duloxetine at 60 mg once daily in elderly patients with major depressive disorder / Joel Raskin en Journal of Clinical Psychopharmacology, Año 2008 - Vol. 28 - No. 1 (Febrero)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 1 (Febrero) . - PP. 32-38 Título : Safety and tolerability of duloxetine at 60 mg once daily in elderly patients with major depressive disorder Tipo de documento: texto impreso Autores: Joel Raskin, Autor ; Curtis G. Wiltse, Autor ; James J. Dinkel, Autor Fecha de publicación: 2023 Artículo en la página: PP. 32-38 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antidepresivos, Trastorno depresivo mayor, Tiofenos - administración y dosificación Resumen: To compare the safety and tolerability profile of duloxetine versus placebo in elderly (≥65 years) patients with major depressive disorder (MDD). Patients were randomized (2:1) to duloxetine 60 mg/d (once daily) (n = 207) or placebo (n = 104) for 8 weeks. Safety and tolerability measures were analyzed in the total cohort of patients, as well as in subgroups defined by age and preexisting hypertension. Link: ./index.php?lvl=notice_display&id=30870 [artículo] Safety and tolerability of duloxetine at 60 mg once daily in elderly patients with major depressive disorder [texto impreso] / Joel Raskin, Autor ; Curtis G. Wiltse, Autor ; James J. Dinkel, Autor . - 2023 . - PP. 32-38. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 1 (Febrero) . - PP. 32-38 Palabras clave: Antidepresivos, Trastorno depresivo mayor, Tiofenos - administración y dosificación Resumen: To compare the safety and tolerability profile of duloxetine versus placebo in elderly (≥65 years) patients with major depressive disorder (MDD). Patients were randomized (2:1) to duloxetine 60 mg/d (once daily) (n = 207) or placebo (n = 104) for 8 weeks. Safety and tolerability measures were analyzed in the total cohort of patients, as well as in subgroups defined by age and preexisting hypertension. Link: ./index.php?lvl=notice_display&id=30870

Once-daily high-dose pindolol for paroxetine-refractory premature ejaculation / Mohammad Reza Safarinejad en Journal of Clinical Psychopharmacology, Año 2008 - Vol. 28 - No. 1 (Febrero)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 1 (Febrero) . - pp. 39-44 Título : Once-daily high-dose pindolol for paroxetine-refractory premature ejaculation : A double-blind, placebo-controlled and randomized study Tipo de documento: texto impreso Autores: Mohammad Reza Safarinejad, Autor Fecha de publicación: 2023 Artículo en la página: pp. 39-44 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Terapia con medicamentos, Eyaculación - efectos de medicamentos, Paroxetina, Pindolol, Inhibidores selectivos de la recaptación de serotonina, Antagonistas de la serotonina, Disfunción sexual fisiológica. Resumen: To evaluate the efficacy and safety of pindolol 7.5 mg/d in delaying of ejaculation in paroxetine-refractory patients. Eighty-six married men (mean age, 33 years) with premature ejaculation unresponsive to paroxetine 20 mg/d given for 2 months or longer were randomized to receive 7.5 mg pindolol (n = 44) (group 1) (PXT + POL) or placebo (n = 42) (group 2) (PXT + PBO) for 6 weeks, while continuing paroxetine. Link: ./index.php?lvl=notice_display&id=30871 [artículo] Once-daily high-dose pindolol for paroxetine-refractory premature ejaculation : A double-blind, placebo-controlled and randomized study [texto impreso] / Mohammad Reza Safarinejad, Autor . - 2023 . - pp. 39-44. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 1 (Febrero) . - pp. 39-44 Palabras clave: Terapia con medicamentos, Eyaculación - efectos de medicamentos, Paroxetina, Pindolol, Inhibidores selectivos de la recaptación de serotonina, Antagonistas de la serotonina, Disfunción sexual fisiológica. Resumen: To evaluate the efficacy and safety of pindolol 7.5 mg/d in delaying of ejaculation in paroxetine-refractory patients. Eighty-six married men (mean age, 33 years) with premature ejaculation unresponsive to paroxetine 20 mg/d given for 2 months or longer were randomized to receive 7.5 mg pindolol (n = 44) (group 1) (PXT + POL) or placebo (n = 42) (group 2) (PXT + PBO) for 6 weeks, while continuing paroxetine. Link: ./index.php?lvl=notice_display&id=30871

Effects of low to moderate acute doses of pramipexole on impulsivity and cognition in healthy volunteers / Ajna Hamidovic en Journal of Clinical Psychopharmacology, Año 2008 - Vol. 28 - No. 1 (Febrero)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 1 (Febrero) . - pp. 45-51 Título : Effects of low to moderate acute doses of pramipexole on impulsivity and cognition in healthy volunteers Tipo de documento: texto impreso Autores: Ajna Hamidovic, Autor ; Un Jung Kang, Autor ; Harriet Wit, Autor Fecha de publicación: 2023 Artículo en la página: pp. 45-51 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Afecto, Benzotiazoles, Cognición - efectos del medicamento, Agonistas de dopamina, Comportamiento impulsivo, Pruebas de personalidad. Resumen: The neurotransmitter dopamine is integrally involved in the rewarding effects of drugs, and it has also been thought to mediate impulsive behaviors in animal models. Most of the studies of drug effects on impulsive behaviors in humans have involved drugs with complex actions on different transmitter systems and different receptor subtypes. Link: ./index.php?lvl=notice_display&id=30872 [artículo] Effects of low to moderate acute doses of pramipexole on impulsivity and cognition in healthy volunteers [texto impreso] / Ajna Hamidovic, Autor ; Un Jung Kang, Autor ; Harriet Wit, Autor . - 2023 . - pp. 45-51. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 1 (Febrero) . - pp. 45-51 Palabras clave: Afecto, Benzotiazoles, Cognición - efectos del medicamento, Agonistas de dopamina, Comportamiento impulsivo, Pruebas de personalidad. Resumen: The neurotransmitter dopamine is integrally involved in the rewarding effects of drugs, and it has also been thought to mediate impulsive behaviors in animal models. Most of the studies of drug effects on impulsive behaviors in humans have involved drugs with complex actions on different transmitter systems and different receptor subtypes. Link: ./index.php?lvl=notice_display&id=30872

Priming stimulation enhances the effectiveness of low-frequency right prefrontal cortex transcranial magnetic stimulation in major depression en Journal of Clinical Psychopharmacology, Año 2008 - Vol. 28 - No. 1 (Febrero)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 1 (Febrero) Título : Priming stimulation enhances the effectiveness of low-frequency right prefrontal cortex transcranial magnetic stimulation in major depression Tipo de documento: texto impreso Fecha de publicación: 2023 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastorno depresivo mayor, Resistencia al medicamento, Corteza prefrontal, Estimulación Magnética Transcraneal. Link: ./index.php?lvl=notice_display&id=30873 [artículo] Priming stimulation enhances the effectiveness of low-frequency right prefrontal cortex transcranial magnetic stimulation in major depression [texto impreso] . - 2023. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 1 (Febrero) Palabras clave: Trastorno depresivo mayor, Resistencia al medicamento, Corteza prefrontal, Estimulación Magnética Transcraneal. Link: ./index.php?lvl=notice_display&id=30873