Artículos

Fluvoxamine-controlled release formulation for the treatment of generalized social anxiety disorder / Jonathan R.T. Davidson en Journal of Clinical Psychopharmacology, Año 2004 - Vol. 24 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 118-125 Título : Fluvoxamine-controlled release formulation for the treatment of generalized social anxiety disorder Tipo de documento: texto impreso Autores: Jonathan R.T. Davidson, Autor ; Jose A. Yaryura-Tobias, Autor ; Robert L. DuPont, Autor Fecha de publicación: 2023 Artículo en la página: pp. 118-125 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antidepresivos, Ansiedad, Fluvoxamina, Disfunción Sexual - Fisiológica, Trastornos del comportamiento social. Resumen: Generalized social anxiety disorder is a highly prevalent anxiety disorder with deleterious effects on social and family relationships, as well as work performance. We report the results of a multicenter, randomized, placebo-controlled trial comparing the efficacy, safety, and tolerability of fluvoxamine controlled release (CR) to placebo in patients with generalized social anxiety disorder. Link: ./index.php?lvl=notice_display&id=30959 [artículo] Fluvoxamine-controlled release formulation for the treatment of generalized social anxiety disorder [texto impreso] / Jonathan R.T. Davidson, Autor ; Jose A. Yaryura-Tobias, Autor ; Robert L. DuPont, Autor . - 2023 . - pp. 118-125. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 118-125 Palabras clave: Antidepresivos, Ansiedad, Fluvoxamina, Disfunción Sexual - Fisiológica, Trastornos del comportamiento social. Resumen: Generalized social anxiety disorder is a highly prevalent anxiety disorder with deleterious effects on social and family relationships, as well as work performance. We report the results of a multicenter, randomized, placebo-controlled trial comparing the efficacy, safety, and tolerability of fluvoxamine controlled release (CR) to placebo in patients with generalized social anxiety disorder. Link: ./index.php?lvl=notice_display&id=30959

"Wish bias" in antidepressant drug trials? / Corrado Barbui en Journal of Clinical Psychopharmacology, Año 2004 - Vol. 24 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 126-130 Título : "Wish bias" in antidepressant drug trials? Tipo de documento: texto impreso Autores: Corrado Barbui, Autor ; Andrea Cipriani, Autor ; Paolo Brambilla, Autor Fecha de publicación: 2023 Artículo en la página: pp. 126-130 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antidepresivos de segunda generación, Trastorno depresivo, Fluoxetina, Diseño de la investigación. Resumen: The present study investigated whether the outcome of randomized clinical trials studying fluoxetine favored fluoxetine, where this was the experimental agent, and favored comparator antidepressants in trials where fluoxetine was the reference agent. A systematic review of all double-blind, randomized clinical trials comparing fluoxetine with any other antidepressant drug in patients suffering from depression was carried out. Link: ./index.php?lvl=notice_display&id=30960 [artículo] "Wish bias" in antidepressant drug trials? [texto impreso] / Corrado Barbui, Autor ; Andrea Cipriani, Autor ; Paolo Brambilla, Autor . - 2023 . - pp. 126-130. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 126-130 Palabras clave: Antidepresivos de segunda generación, Trastorno depresivo, Fluoxetina, Diseño de la investigación. Resumen: The present study investigated whether the outcome of randomized clinical trials studying fluoxetine favored fluoxetine, where this was the experimental agent, and favored comparator antidepressants in trials where fluoxetine was the reference agent. A systematic review of all double-blind, randomized clinical trials comparing fluoxetine with any other antidepressant drug in patients suffering from depression was carried out. Link: ./index.php?lvl=notice_display&id=30960

Paroxetine treatment of depression with posttraumatic stress disorder Effects on autonomic reactivity and cortisol secretion / Phebe Tucker en Journal of Clinical Psychopharmacology, Año 2004 - Vol. 24 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 131-140 Título : Paroxetine treatment of depression with posttraumatic stress disorder Effects on autonomic reactivity and cortisol secretion Tipo de documento: texto impreso Autores: Phebe Tucker, Autor ; Katherine L. Beebe, Autor ; Christie Burgin, Autor Fecha de publicación: 2023 Artículo en la página: pp. 131-140 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Sistema Nervioso Autónomo, Trastorno Depresivo, Sistemas neurosecretores, Paroxetina, Trastornos de estrés postraumático. Resumen: Effects of paroxetine treatment of comorbid depression and posttraumatic stress disorder (PTSD) on subjective symptoms, autonomic reactivity, and diurnal salivary cortisols were assessed prospectively. Cross-sectional baseline psychophysiologic assessments of 22 patients with depression + PTSD, 21 with depression alone, and 20 asymptomatic, previously traumatized controls found that comorbid patients had higher blood pressure and heart rate reactivity to individualized trauma scripts than purely depressed and control groups. Link: ./index.php?lvl=notice_display&id=30961 [artículo] Paroxetine treatment of depression with posttraumatic stress disorder Effects on autonomic reactivity and cortisol secretion [texto impreso] / Phebe Tucker, Autor ; Katherine L. Beebe, Autor ; Christie Burgin, Autor . - 2023 . - pp. 131-140. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 131-140 Palabras clave: Sistema Nervioso Autónomo, Trastorno Depresivo, Sistemas neurosecretores, Paroxetina, Trastornos de estrés postraumático. Resumen: Effects of paroxetine treatment of comorbid depression and posttraumatic stress disorder (PTSD) on subjective symptoms, autonomic reactivity, and diurnal salivary cortisols were assessed prospectively. Cross-sectional baseline psychophysiologic assessments of 22 patients with depression + PTSD, 21 with depression alone, and 20 asymptomatic, previously traumatized controls found that comorbid patients had higher blood pressure and heart rate reactivity to individualized trauma scripts than purely depressed and control groups. Link: ./index.php?lvl=notice_display&id=30961

Efficacy of the novel anxiolytic pregabalin in social anxiety disorder / Atul C. Pande en Journal of Clinical Psychopharmacology, Año 2004 - Vol. 24 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 141-149 Título : Efficacy of the novel anxiolytic pregabalin in social anxiety disorder : A placebo-controlled, multicenter study Tipo de documento: texto impreso Autores: Atul C. Pande, Autor ; Douglas E. Feltner, Autor ; James W. Jefferson, Autor Fecha de publicación: 2023 Artículo en la página: pp. 141-149 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Ansiolíticos, Ansiedad, Pregabalina, Trastornos del comportamiento social, Aumento de peso - efectos de medicamentos. Resumen: Pregabalin is a novel compound in the development for the treatment of anxiety disorders. The safety and efficacy of pregabalin for the treatment of social anxiety disorder was evaluated in a double-blind, multicenter clinical trial in which 135 patients were randomized to 10 weeks of double-blind treatment with either pregabalin 150 mg/d, pregabalin 600 mg/d, or placebo. Link: ./index.php?lvl=notice_display&id=30962 [artículo] Efficacy of the novel anxiolytic pregabalin in social anxiety disorder : A placebo-controlled, multicenter study [texto impreso] / Atul C. Pande, Autor ; Douglas E. Feltner, Autor ; James W. Jefferson, Autor . - 2023 . - pp. 141-149. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 141-149 Palabras clave: Ansiolíticos, Ansiedad, Pregabalina, Trastornos del comportamiento social, Aumento de peso - efectos de medicamentos. Resumen: Pregabalin is a novel compound in the development for the treatment of anxiety disorders. The safety and efficacy of pregabalin for the treatment of social anxiety disorder was evaluated in a double-blind, multicenter clinical trial in which 135 patients were randomized to 10 weeks of double-blind treatment with either pregabalin 150 mg/d, pregabalin 600 mg/d, or placebo. Link: ./index.php?lvl=notice_display&id=30962

Chronic lithium administration enhances noradrenergic responses to intravenous administration of the α2 antagonist idazoxan in healthy volunteers / Aysegül Özerdem en Journal of Clinical Psychopharmacology, Año 2004 - Vol. 24 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 150-154 Título : Chronic lithium administration enhances noradrenergic responses to intravenous administration of the α2 antagonist idazoxan in healthy volunteers Tipo de documento: texto impreso Autores: Aysegül Özerdem, Autor ; Mark E. Schmidt, Autor ; Husseini K. Manji, Autor Fecha de publicación: 2023 Artículo en la página: pp. 150-154 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antagonistas alfa adrenérgicos, Agentes antimaníacos, Hemodinámica, Idazoxano, Carbonato de litio, Noradrenalina, Características sexuales Resumen: The acute and chronic effects of lithium carbonate administration at therapeutic blood levels on peripheral noradrenergic activity and sympathetic responses to α2 adrenoceptor blockade were examined in 10 medically and psychiatrically healthy volunteers. Supine resting levels of plasma norepinephrine and the increases in norepinephrine following intravenous infusion of 200 μg/kg of idazoxan, a selective α2 adrenoceptor antagonist, were determined before lithium (Li+) administration and after 5 days and after 4 weeks of daily Li+ treatment. Link: ./index.php?lvl=notice_display&id=30963 [artículo] Chronic lithium administration enhances noradrenergic responses to intravenous administration of the α2 antagonist idazoxan in healthy volunteers [texto impreso] / Aysegül Özerdem, Autor ; Mark E. Schmidt, Autor ; Husseini K. Manji, Autor . - 2023 . - pp. 150-154. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 150-154 Palabras clave: Antagonistas alfa adrenérgicos, Agentes antimaníacos, Hemodinámica, Idazoxano, Carbonato de litio, Noradrenalina, Características sexuales Resumen: The acute and chronic effects of lithium carbonate administration at therapeutic blood levels on peripheral noradrenergic activity and sympathetic responses to α2 adrenoceptor blockade were examined in 10 medically and psychiatrically healthy volunteers. Supine resting levels of plasma norepinephrine and the increases in norepinephrine following intravenous infusion of 200 μg/kg of idazoxan, a selective α2 adrenoceptor antagonist, were determined before lithium (Li+) administration and after 5 days and after 4 weeks of daily Li+ treatment. Link: ./index.php?lvl=notice_display&id=30963

The impact of antipsychotics on psychomotor performance with regards to car driving skills / Alexander Brunnauer en Journal of Clinical Psychopharmacology, Año 2004 - Vol. 24 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 155-160 Título : The impact of antipsychotics on psychomotor performance with regards to car driving skills Tipo de documento: texto impreso Autores: Alexander Brunnauer, Autor ; Gerd Laux, Autor ; Elisabeth Geiger, Autor Fecha de publicación: 2023 Artículo en la página: pp. 155-160 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Conducción de automóviles, Clozapina, Flupentixol, Rendimiento psicomotor, Esquizofrenia, Psicología esquizofrénica, Percepción visual. Resumen: Cognitive and psychomotor impairments are a core feature of most patients with schizophrenia and may have an important influence on driving ability. The present study investigated the effects of neuroleptic monotherapy on psychomotor functions related to car driving skills in schizophrenic patients. Link: ./index.php?lvl=notice_display&id=30964 [artículo] The impact of antipsychotics on psychomotor performance with regards to car driving skills [texto impreso] / Alexander Brunnauer, Autor ; Gerd Laux, Autor ; Elisabeth Geiger, Autor . - 2023 . - pp. 155-160. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 155-160 Palabras clave: Antipsicóticos, Conducción de automóviles, Clozapina, Flupentixol, Rendimiento psicomotor, Esquizofrenia, Psicología esquizofrénica, Percepción visual. Resumen: Cognitive and psychomotor impairments are a core feature of most patients with schizophrenia and may have an important influence on driving ability. The present study investigated the effects of neuroleptic monotherapy on psychomotor functions related to car driving skills in schizophrenic patients. Link: ./index.php?lvl=notice_display&id=30964

Prolactin levels and erectile function in patients treated with risperidone / John J. Spollen en Journal of Clinical Psychopharmacology, Año 2004 - Vol. 24 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 161-166 Título : Prolactin levels and erectile function in patients treated with risperidone Tipo de documento: texto impreso Autores: John J. Spollen, Autor ; Robert G. Wooten, Autor ; Christopher Cargile, Autor Fecha de publicación: 2023 Artículo en la página: pp. 161-166 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Afecto, Antipsicóticos, Ritmo circadiano, Disfunción eréctil, Erección, Prolactina, Risperidona, Esquizofrenia, Testosterona. Resumen: Treatment with risperidone is associated with prolactin (PRL) elevation, and PRL elevations are associated with erectile dysfunction (ED). We evaluated whether the PRL elevations caused by risperidone treatment of subjects with schizophrenia are associated with objective measures of erectile function. Link: ./index.php?lvl=notice_display&id=30965 [artículo] Prolactin levels and erectile function in patients treated with risperidone [texto impreso] / John J. Spollen, Autor ; Robert G. Wooten, Autor ; Christopher Cargile, Autor . - 2023 . - pp. 161-166. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 161-166 Palabras clave: Afecto, Antipsicóticos, Ritmo circadiano, Disfunción eréctil, Erección, Prolactina, Risperidona, Esquizofrenia, Testosterona. Resumen: Treatment with risperidone is associated with prolactin (PRL) elevation, and PRL elevations are associated with erectile dysfunction (ED). We evaluated whether the PRL elevations caused by risperidone treatment of subjects with schizophrenia are associated with objective measures of erectile function. Link: ./index.php?lvl=notice_display&id=30965

Clozapine treatment of adolescents with posttraumatic stress disorder and psychotic symptoms / Malcolm Wheatley en Journal of Clinical Psychopharmacology, Año 2004 - Vol. 24 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 167-173 Título : Clozapine treatment of adolescents with posttraumatic stress disorder and psychotic symptoms Tipo de documento: texto impreso Autores: Malcolm Wheatley, Autor ; Helen Reader, Autor ; Geoff Brown, Autor Fecha de publicación: 2023 Artículo en la página: pp. 167-173 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Atipsicóticos, Clozapina, Trastorno Depresivo, Pacientes hospitalizados, Trastornos psicóticos, Comportamiento autolesivo, Trastornos de estrés postraumático Resumen: This study investigates the efficacy of clozapine in treatment-resistant abused adolescents detained in a secure environment who present with chronic posttraumatic stress disorder and psychotic symptoms. All participants had received at least 2 trials of conventional neuroleptic medication prior to starting clozapine. Link: ./index.php?lvl=notice_display&id=30966 [artículo] Clozapine treatment of adolescents with posttraumatic stress disorder and psychotic symptoms [texto impreso] / Malcolm Wheatley, Autor ; Helen Reader, Autor ; Geoff Brown, Autor . - 2023 . - pp. 167-173. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 167-173 Palabras clave: Atipsicóticos, Clozapina, Trastorno Depresivo, Pacientes hospitalizados, Trastornos psicóticos, Comportamiento autolesivo, Trastornos de estrés postraumático Resumen: This study investigates the efficacy of clozapine in treatment-resistant abused adolescents detained in a secure environment who present with chronic posttraumatic stress disorder and psychotic symptoms. All participants had received at least 2 trials of conventional neuroleptic medication prior to starting clozapine. Link: ./index.php?lvl=notice_display&id=30966

Postintervention effect of nicotine replacement therapy on smoking reduction in smokers who are unwilling to quit / Jean François Etter en Journal of Clinical Psychopharmacology, Año 2004 - Vol. 24 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 174-179 Título : Postintervention effect of nicotine replacement therapy on smoking reduction in smokers who are unwilling to quit : Randomized trial Tipo de documento: texto impreso Autores: Jean François Etter, Autor ; Evelyne Laszlo, Autor ; Thomas V. Perneger, Autor Fecha de publicación: 2023 Artículo en la página: pp. 174-179 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Nicotina, Agonistas nicotínicos, Tabaquismo. Resumen: The objective of this study was to assess the postintervention effect of nicotine replacement therapy on reduction of cigarette consumption 1.5 years after the end of a 6-month treatment. Heavy smokers who had no intention of quitting smoking were recruited from the general population and were randomly assigned to a treatment of nicotine (choice of a 15-mg nicotine patch, a 4-mg nicotine gum, and/or a 10-mg nicotine inhaler, n = 265), matching placebo products (n = 269), or no intervention (n = 389). Products were sent to participants by mail. Link: ./index.php?lvl=notice_display&id=30967 [artículo] Postintervention effect of nicotine replacement therapy on smoking reduction in smokers who are unwilling to quit : Randomized trial [texto impreso] / Jean François Etter, Autor ; Evelyne Laszlo, Autor ; Thomas V. Perneger, Autor . - 2023 . - pp. 174-179. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 174-179 Palabras clave: Nicotina, Agonistas nicotínicos, Tabaquismo. Resumen: The objective of this study was to assess the postintervention effect of nicotine replacement therapy on reduction of cigarette consumption 1.5 years after the end of a 6-month treatment. Heavy smokers who had no intention of quitting smoking were recruited from the general population and were randomly assigned to a treatment of nicotine (choice of a 15-mg nicotine patch, a 4-mg nicotine gum, and/or a 10-mg nicotine inhaler, n = 265), matching placebo products (n = 269), or no intervention (n = 389). Products were sent to participants by mail. Link: ./index.php?lvl=notice_display&id=30967

Effects of isradipine on cocaine induced subjective mood / Bankole A. Johnson en Journal of Clinical Psychopharmacology, Año 2004 - Vol. 24 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 180-191 Título : Effects of isradipine on cocaine induced subjective mood Tipo de documento: texto impreso Autores: Bankole A. Johnson, Autor ; John D. Roache, Autor ; Nassima Ait Daoud, Autor Fecha de publicación: 2023 Artículo en la página: pp. 180-191 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Afecto, Bloqueadores de los canales de calcio, Bloqueadores de los canales de calcio, Cocaína - farmacología, Trastornos relacionados con la cocaína, Dopamina, Isradipina. Resumen: We hypothesized that in humans, as in animals, isradipine, a dihydropyridine-class calcium channel antagonist, would antagonize cocaine's rewarding effects, based on preclinical evidence that isradipine inhibits cocaine-mediated increases in mesolimbic dopamine (DA), thereby reducing cocaine's abuse liability. Confirmation of our hypothesis would make isradipine a promising medication for treating cocaine dependence. Link: ./index.php?lvl=notice_display&id=30968 [artículo] Effects of isradipine on cocaine induced subjective mood [texto impreso] / Bankole A. Johnson, Autor ; John D. Roache, Autor ; Nassima Ait Daoud, Autor . - 2023 . - pp. 180-191. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 180-191 Palabras clave: Afecto, Bloqueadores de los canales de calcio, Bloqueadores de los canales de calcio, Cocaína - farmacología, Trastornos relacionados con la cocaína, Dopamina, Isradipina. Resumen: We hypothesized that in humans, as in animals, isradipine, a dihydropyridine-class calcium channel antagonist, would antagonize cocaine's rewarding effects, based on preclinical evidence that isradipine inhibits cocaine-mediated increases in mesolimbic dopamine (DA), thereby reducing cocaine's abuse liability. Confirmation of our hypothesis would make isradipine a promising medication for treating cocaine dependence. Link: ./index.php?lvl=notice_display&id=30968

Dose response and dose equivalence of antipsychotics / John Marcell Davis en Journal of Clinical Psychopharmacology, Año 2004 - Vol. 24 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 192-208 Título : Dose response and dose equivalence of antipsychotics Tipo de documento: texto impreso Autores: John Marcell Davis, Autor ; Nancy Chen, Autor Fecha de publicación: 2023 Artículo en la página: pp. 192-208 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Resistencia al medicamento, Trastornos psicóticos. Resumen: We review evidence from randomized, placebo-controlled studies of patients with schizophrenia or schizoaffective disorder, which compared 2 or more doses of an antipsychotic to calculate the dose-response curve for each first-generation (typical) antipsychotic (FGA) or second-generation (atypical) antipsychotic (SGA) and as a group (based on dose equivalence). Link: ./index.php?lvl=notice_display&id=30969 [artículo] Dose response and dose equivalence of antipsychotics [texto impreso] / John Marcell Davis, Autor ; Nancy Chen, Autor . - 2023 . - pp. 192-208. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 192-208 Palabras clave: Antipsicóticos, Resistencia al medicamento, Trastornos psicóticos. Resumen: We review evidence from randomized, placebo-controlled studies of patients with schizophrenia or schizoaffective disorder, which compared 2 or more doses of an antipsychotic to calculate the dose-response curve for each first-generation (typical) antipsychotic (FGA) or second-generation (atypical) antipsychotic (SGA) and as a group (based on dose equivalence). Link: ./index.php?lvl=notice_display&id=30969