Artículos

Tolerability and efficacy of clozapine combined with lithium in schizophrenia and schizoaffective disorder / Joyce G. Small en Journal of Clinical Psychopharmacology, Año 2003 - Vol. 23 - No. 3 (Junio)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 3 (Junio) . - pp. 223-228 Título : Tolerability and efficacy of clozapine combined with lithium in schizophrenia and schizoaffective disorder Tipo de documento: texto impreso Autores: Joyce G. Small, Autor ; Marietta H. Klapper, Autor ; Frederick W. Malloy, Autor Fecha de publicación: 2023 Artículo en la página: pp. 223-228 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Clozapina, Terapia medicamentosa, Cloruro de Litio, Trastornos psicóticos, Esquizofrenia. Resumen: The safety and tolerability of clozapine combined with lithium were investigated because of potential additive risks as well as frequent usage in clinical practice. Ten hospitalized schizophrenic and 10 schizoaffective patients receiving clozapine maintenance therapy with partial therapeutic response were studied in a randomized controlled trial. Link: ./index.php?lvl=notice_display&id=31017 [artículo] Tolerability and efficacy of clozapine combined with lithium in schizophrenia and schizoaffective disorder [texto impreso] / Joyce G. Small, Autor ; Marietta H. Klapper, Autor ; Frederick W. Malloy, Autor . - 2023 . - pp. 223-228. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 3 (Junio) . - pp. 223-228 Palabras clave: Clozapina, Terapia medicamentosa, Cloruro de Litio, Trastornos psicóticos, Esquizofrenia. Resumen: The safety and tolerability of clozapine combined with lithium were investigated because of potential additive risks as well as frequent usage in clinical practice. Ten hospitalized schizophrenic and 10 schizoaffective patients receiving clozapine maintenance therapy with partial therapeutic response were studied in a randomized controlled trial. Link: ./index.php?lvl=notice_display&id=31017

Ziprasidone metabolism, aldehyde oxidase, and clinical implications / Christine Beedham en Journal of Clinical Psychopharmacology, Año 2003 - Vol. 23 - No. 3 (Junio)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 3 (Junio) . - pp. 229-232 Título : Ziprasidone metabolism, aldehyde oxidase, and clinical implications Tipo de documento: texto impreso Autores: Christine Beedham, Autor ; Jeffrey J. Miceli, Autor ; R. Scott Obach, Autor Fecha de publicación: 2023 Artículo en la página: pp. 229-232 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Sistema enzimático citocromo P-450, Interacciones farmacológicas, Piperazinas, Tiazoles. Resumen: Ziprasidone (Geodon, Zeldox), a recently approved atypical antipsychotic agent for the treatment of schizophrenia, undergoes extensive metabolism in humans with very little ( Link: ./index.php?lvl=notice_display&id=31018 [artículo] Ziprasidone metabolism, aldehyde oxidase, and clinical implications [texto impreso] / Christine Beedham, Autor ; Jeffrey J. Miceli, Autor ; R. Scott Obach, Autor . - 2023 . - pp. 229-232. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 3 (Junio) . - pp. 229-232 Palabras clave: Sistema enzimático citocromo P-450, Interacciones farmacológicas, Piperazinas, Tiazoles. Resumen: Ziprasidone (Geodon, Zeldox), a recently approved atypical antipsychotic agent for the treatment of schizophrenia, undergoes extensive metabolism in humans with very little ( Link: ./index.php?lvl=notice_display&id=31018

Neurochemical and psychotropic effects of bupropion in healthy male subjects / Gabriella Gobbi en Journal of Clinical Psychopharmacology, Año 2003 - Vol. 23 - No. 3 (Junio)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 3 (Junio) . - pp. 233-239 Título : Neurochemical and psychotropic effects of bupropion in healthy male subjects Tipo de documento: texto impreso Autores: Gabriella Gobbi, Autor ; Susan Slater, Autor ; Nathalie Boucher, Autor Fecha de publicación: 2023 Artículo en la página: pp. 233-239 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Afecto, Presión arterial, Bupropión, Glicoproteínas de membrana, Pruebas Neuropsicológicas, Psicotrópicos, Serotonina. Resumen: Bupropion is a weak inhibitor of noradrenaline (NE) and dopamine (DA) reuptake and has no direct action on serotonin (5-HT) neuronal elements. In the rat brain, bupropion suppresses NE neuron firing activity via the activation of α2-adrenoceptors and increases that of 5-HT neurons through an indirect action on NE neurons. Link: ./index.php?lvl=notice_display&id=31019 [artículo] Neurochemical and psychotropic effects of bupropion in healthy male subjects [texto impreso] / Gabriella Gobbi, Autor ; Susan Slater, Autor ; Nathalie Boucher, Autor . - 2023 . - pp. 233-239. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 3 (Junio) . - pp. 233-239 Palabras clave: Afecto, Presión arterial, Bupropión, Glicoproteínas de membrana, Pruebas Neuropsicológicas, Psicotrópicos, Serotonina. Resumen: Bupropion is a weak inhibitor of noradrenaline (NE) and dopamine (DA) reuptake and has no direct action on serotonin (5-HT) neuronal elements. In the rat brain, bupropion suppresses NE neuron firing activity via the activation of α2-adrenoceptors and increases that of 5-HT neurons through an indirect action on NE neurons. Link: ./index.php?lvl=notice_display&id=31019

A randomized, double-blind, placebo-controlled, fixed-dose, multicenter study of pregabalin in patients with generalized anxiety disorder / Douglas E. Feltner en Journal of Clinical Psychopharmacology, Año 2003 - Vol. 23 - No. 3 (Junio)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 3 (Junio) . - pp. 240-249 Título : A randomized, double-blind, placebo-controlled, fixed-dose, multicenter study of pregabalin in patients with generalized anxiety disorder Tipo de documento: texto impreso Autores: Douglas E. Feltner, Autor ; Jerri G. Crockatt, Autor ; Steven J. Dubovsky, Autor Fecha de publicación: 2023 Artículo en la página: pp. 240-249 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastornos de ansiedad, Pruebas Neuropsicológicas, Pregabalina, Ácido gamma-aminobutírico. Resumen: Pregabalin is a novel compound under development for the treatment of several types of anxiety disorders. To obtain an initial evaluation of the efficacy and safety of pregabalin in the treatment of generalized anxiety disorder (GAD), we conducted a double-blind, fixed-dose, parallel-group, placebo and active-controlled multicenter 4-week study that compared 271 patients randomized to receive pregabalin 50 mg tid (N = 70), pregabalin 200 mg tid (N = 66), placebo (N = 67), or lorazepam 2 mg tid (N = 68), followed by a 1-week double-blind taper. Link: ./index.php?lvl=notice_display&id=31020 [artículo] A randomized, double-blind, placebo-controlled, fixed-dose, multicenter study of pregabalin in patients with generalized anxiety disorder [texto impreso] / Douglas E. Feltner, Autor ; Jerri G. Crockatt, Autor ; Steven J. Dubovsky, Autor . - 2023 . - pp. 240-249. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 3 (Junio) . - pp. 240-249 Palabras clave: Trastornos de ansiedad, Pruebas Neuropsicológicas, Pregabalina, Ácido gamma-aminobutírico. Resumen: Pregabalin is a novel compound under development for the treatment of several types of anxiety disorders. To obtain an initial evaluation of the efficacy and safety of pregabalin in the treatment of generalized anxiety disorder (GAD), we conducted a double-blind, fixed-dose, parallel-group, placebo and active-controlled multicenter 4-week study that compared 271 patients randomized to receive pregabalin 50 mg tid (N = 70), pregabalin 200 mg tid (N = 66), placebo (N = 67), or lorazepam 2 mg tid (N = 68), followed by a 1-week double-blind taper. Link: ./index.php?lvl=notice_display&id=31020

Predictors of outcome following venlafaxine extended-release treatment of dsm-iv generalized anxiety disorder: a pooled analysis of short- and long-term studies / Mark H. Pollack en Journal of Clinical Psychopharmacology, Año 2003 - Vol. 23 - No. 3 (Junio)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 3 (Junio) . - pp. 250-259 Título : Predictors of outcome following venlafaxine extended-release treatment of dsm-iv generalized anxiety disorder: a pooled analysis of short- and long-term studies Tipo de documento: texto impreso Autores: Mark H. Pollack, Autor ; Paolo Meoni, Autor ; Michael W. Otto, Autor Fecha de publicación: 2023 Artículo en la página: pp. 250-259 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastornos de ansiedad, Ciclohexanoles, Clorhidrato de venlafaxina Resumen: This pooled analysis evaluated potential predictive abilities of baseline demographic factors, psychiatric history, and DSM-IV diagnostic criteria for short- and long-term outcome after treatment with venlafaxine extended release (XR) or placebo in patients with generalized anxiety disorder (GAD). Link: ./index.php?lvl=notice_display&id=31021 [artículo] Predictors of outcome following venlafaxine extended-release treatment of dsm-iv generalized anxiety disorder: a pooled analysis of short- and long-term studies [texto impreso] / Mark H. Pollack, Autor ; Paolo Meoni, Autor ; Michael W. Otto, Autor . - 2023 . - pp. 250-259. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 3 (Junio) . - pp. 250-259 Palabras clave: Trastornos de ansiedad, Ciclohexanoles, Clorhidrato de venlafaxina Resumen: This pooled analysis evaluated potential predictive abilities of baseline demographic factors, psychiatric history, and DSM-IV diagnostic criteria for short- and long-term outcome after treatment with venlafaxine extended release (XR) or placebo in patients with generalized anxiety disorder (GAD). Link: ./index.php?lvl=notice_display&id=31021

Acute pharmacological effects of temazepam, diphenhydramine, and valerian in healthy elderly subjects / Jennifer R. Glass en Journal of Clinical Psychopharmacology, Año 2003 - Vol. 23 - No. 3 (Junio)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 3 (Junio) . - pp. 260-268 Título : Acute pharmacological effects of temazepam, diphenhydramine, and valerian in healthy elderly subjects Tipo de documento: texto impreso Autores: Jennifer R. Glass, Autor ; Beth A. Sproule, Autor ; Nathan Herrmann, Autor Fecha de publicación: 2023 Artículo en la página: pp. 260-268 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Difenhidramina, Relación Dosis-Respuesta, Rendimiento psicomotor, Efectos del sueño, Sueño - fisiología, Temazepam, Valeriana. Resumen: Elderly insomniacs are often treated pharmacologically with benzodiazepines, antihistamines, or natural products. A double-blind, randomized, crossover, placebo-controlled study was performed to assess the comparative pharmacodynamics of single doses of temazepam (15 and 30 mg), diphenhydramine (50 and 75 mg), and valerian (400 and 800 mg) in 14 healthy elderly volunteers (mean age, 71.6 years; range, 65–89). Link: ./index.php?lvl=notice_display&id=31022 [artículo] Acute pharmacological effects of temazepam, diphenhydramine, and valerian in healthy elderly subjects [texto impreso] / Jennifer R. Glass, Autor ; Beth A. Sproule, Autor ; Nathan Herrmann, Autor . - 2023 . - pp. 260-268. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 3 (Junio) . - pp. 260-268 Palabras clave: Difenhidramina, Relación Dosis-Respuesta, Rendimiento psicomotor, Efectos del sueño, Sueño - fisiología, Temazepam, Valeriana. Resumen: Elderly insomniacs are often treated pharmacologically with benzodiazepines, antihistamines, or natural products. A double-blind, randomized, crossover, placebo-controlled study was performed to assess the comparative pharmacodynamics of single doses of temazepam (15 and 30 mg), diphenhydramine (50 and 75 mg), and valerian (400 and 800 mg) in 14 healthy elderly volunteers (mean age, 71.6 years; range, 65–89). Link: ./index.php?lvl=notice_display&id=31022

Comparative abuse liability and pharmacological effects of meprobamate, triazolam, and butabarbital / Laurie A. Zawertailo en Journal of Clinical Psychopharmacology, Año 2003 - Vol. 23 - No. 3 (Junio)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 3 (Junio) . - pp. 269-280 Título : Comparative abuse liability and pharmacological effects of meprobamate, triazolam, and butabarbital Tipo de documento: texto impreso Autores: Laurie A. Zawertailo, Autor ; Usoa E. Busto, Autor ; Howard L. Kaplan, Autor Fecha de publicación: 2023 Artículo en la página: pp. 269-280 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Barbitúricos, Comportamiento adictivo, Adicción - psicología, Meprobamato, Trastornos relacionados con sustancias, Triazolam. Resumen: Implementation of regulations to control the prescribing of benzodiazepines in New York State in 1989 resulted in a 55% decrease in benzodiazepine prescribing, with a concomitant increase in the rates of prescribing older sedativehypnotic compounds such as butabarbital (30% increase) and meprobamate (125% increase). Link: ./index.php?lvl=notice_display&id=31023 [artículo] Comparative abuse liability and pharmacological effects of meprobamate, triazolam, and butabarbital [texto impreso] / Laurie A. Zawertailo, Autor ; Usoa E. Busto, Autor ; Howard L. Kaplan, Autor . - 2023 . - pp. 269-280. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 3 (Junio) . - pp. 269-280 Palabras clave: Barbitúricos, Comportamiento adictivo, Adicción - psicología, Meprobamato, Trastornos relacionados con sustancias, Triazolam. Resumen: Implementation of regulations to control the prescribing of benzodiazepines in New York State in 1989 resulted in a 55% decrease in benzodiazepine prescribing, with a concomitant increase in the rates of prescribing older sedativehypnotic compounds such as butabarbital (30% increase) and meprobamate (125% increase). Link: ./index.php?lvl=notice_display&id=31023

Dose-ranging kinetics and behavioral pharmacology of naltrexone and acamprosate, both alone and combined, in alcohol-dependent subjects / Bankole A. Johnson en Journal of Clinical Psychopharmacology, Año 2003 - Vol. 23 - No. 3 (Junio)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 3 (Junio) . - pp. 281-293 Título : Dose-ranging kinetics and behavioral pharmacology of naltrexone and acamprosate, both alone and combined, in alcohol-dependent subjects Tipo de documento: texto impreso Autores: Bankole A. Johnson, Autor ; Stephanie S. O’Malley, Autor Fecha de publicación: 2023 Artículo en la página: pp. 281-293 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Alcoholismo, Terapia con medicamentos, Naltrexona, Pruebas neuropsicológicas, Taurina. Resumen: We examined kinetic and dynamic factors to determine the pharmacological and behavioral safety and tolerability of low versus high doses of an opiate antagonist, naltrexone (50 mg/day vs. 100 mg/day), and acamprosate (2 g/day vs. 3 g/day), a functional N-methyl-D-aspartate receptor antagonist, both independently and combined, among non-treatmentseeking, alcohol-dependent individuals. Link: ./index.php?lvl=notice_display&id=31024 [artículo] Dose-ranging kinetics and behavioral pharmacology of naltrexone and acamprosate, both alone and combined, in alcohol-dependent subjects [texto impreso] / Bankole A. Johnson, Autor ; Stephanie S. O’Malley, Autor . - 2023 . - pp. 281-293. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 3 (Junio) . - pp. 281-293 Palabras clave: Alcoholismo, Terapia con medicamentos, Naltrexona, Pruebas neuropsicológicas, Taurina. Resumen: We examined kinetic and dynamic factors to determine the pharmacological and behavioral safety and tolerability of low versus high doses of an opiate antagonist, naltrexone (50 mg/day vs. 100 mg/day), and acamprosate (2 g/day vs. 3 g/day), a functional N-methyl-D-aspartate receptor antagonist, both independently and combined, among non-treatmentseeking, alcohol-dependent individuals. Link: ./index.php?lvl=notice_display&id=31024

Targeted naltrexone for early problem drinkers / Henry R. Kranzler en Journal of Clinical Psychopharmacology, Año 2003 - Vol. 23 - No. 3 (Junio)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 3 (Junio) . - pp. 294-304 Título : Targeted naltrexone for early problem drinkers Tipo de documento: texto impreso Autores: Henry R. Kranzler, Autor ; Stephen Armeli, Autor ; Howard Tennen, Autor Fecha de publicación: 2023 Artículo en la página: pp. 294-304 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Consumo de alcohol, Naltrexona - uso terapéutico Resumen: Most published studies of the efficacy of naltrexone for alcohol treatment have focused on daily medication for relapse prevention among abstinent alcoholics. The present study compared the effects of naltrexone with those of placebo in a sample of early problem drinkers who received study medication either daily or targeted to situations identified by the patients as being high risk for heavy drinking. Link: ./index.php?lvl=notice_display&id=31025 [artículo] Targeted naltrexone for early problem drinkers [texto impreso] / Henry R. Kranzler, Autor ; Stephen Armeli, Autor ; Howard Tennen, Autor . - 2023 . - pp. 294-304. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 3 (Junio) . - pp. 294-304 Palabras clave: Consumo de alcohol, Naltrexona - uso terapéutico Resumen: Most published studies of the efficacy of naltrexone for alcohol treatment have focused on daily medication for relapse prevention among abstinent alcoholics. The present study compared the effects of naltrexone with those of placebo in a sample of early problem drinkers who received study medication either daily or targeted to situations identified by the patients as being high risk for heavy drinking. Link: ./index.php?lvl=notice_display&id=31025