Artículos

The efficacy and safety of olanzapine for the treatment of geriatric psychosis / Jen Ping Hwang en Journal of Clinical Psychopharmacology, Año 2003 - Vol. 23 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 2 (Abril) . - pp. 113-118 Título : The efficacy and safety of olanzapine for the treatment of geriatric psychosis Tipo de documento: texto impreso Autores: Jen Ping Hwang, Autor ; Cheng Hung Yang, Autor Fecha de publicación: 2023 Artículo en la página: pp. 113-118 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Benzodiazepinas, Olanzapina, Pirenzepina, Trastornos psicóticos. Resumen: Elderly psychiatric patients often present with psychotic symptoms that need antipsychotic treatment. Olanzapine is one of the atypical antipsychotics with efficacy for psychotic symptoms and a safer side-effect profile than typical antipsychotics. This study was conducted to assess the efficacy and safety of olanzapine for treatment of geriatric psychosis. Link: ./index.php?lvl=notice_display&id=31027 [artículo] The efficacy and safety of olanzapine for the treatment of geriatric psychosis [texto impreso] / Jen Ping Hwang, Autor ; Cheng Hung Yang, Autor . - 2023 . - pp. 113-118. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 2 (Abril) . - pp. 113-118 Palabras clave: Antipsicóticos, Benzodiazepinas, Olanzapina, Pirenzepina, Trastornos psicóticos. Resumen: Elderly psychiatric patients often present with psychotic symptoms that need antipsychotic treatment. Olanzapine is one of the atypical antipsychotics with efficacy for psychotic symptoms and a safer side-effect profile than typical antipsychotics. This study was conducted to assess the efficacy and safety of olanzapine for treatment of geriatric psychosis. Link: ./index.php?lvl=notice_display&id=31027

Role of the smoking-induced cytochrome p450 (cyp)1a2 and polymorphic cyp2d6 in steady-state concentration of olanzapine / Juan Antonio Carrillo en Journal of Clinical Psychopharmacology, Año 2003 - Vol. 23 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 2 (Abril) . - pp. 119-127 Título : Role of the smoking-induced cytochrome p450 (cyp)1a2 and polymorphic cyp2d6 in steady-state concentration of olanzapine Tipo de documento: texto impreso Autores: Juan Antonio Carrillo, Autor ; Angustias G. Herráiz, Autor ; Sara Isabel Ramos, Autor Fecha de publicación: 2023 Artículo en la página: pp. 119-127 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Benzodiazepinas, Cafeína, Citocromo P-450 CYP1A2, Pirenzepina, Esquizofrenia. Resumen: This study investigated whether the smokinginducible cytochrome P450 (CYP) 1A2 and the polymorphic CYP2D6 play significant roles in the metabolism of olanzapine and its clinical effects at steady-state treatment. Caffeine and debrisoquine were used as measures of CYP1A2 and CYP2D6, respectively. Link: ./index.php?lvl=notice_display&id=31028 [artículo] Role of the smoking-induced cytochrome p450 (cyp)1a2 and polymorphic cyp2d6 in steady-state concentration of olanzapine [texto impreso] / Juan Antonio Carrillo, Autor ; Angustias G. Herráiz, Autor ; Sara Isabel Ramos, Autor . - 2023 . - pp. 119-127. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 2 (Abril) . - pp. 119-127 Palabras clave: Antipsicóticos, Benzodiazepinas, Cafeína, Citocromo P-450 CYP1A2, Pirenzepina, Esquizofrenia. Resumen: This study investigated whether the smokinginducible cytochrome P450 (CYP) 1A2 and the polymorphic CYP2D6 play significant roles in the metabolism of olanzapine and its clinical effects at steady-state treatment. Caffeine and debrisoquine were used as measures of CYP1A2 and CYP2D6, respectively. Link: ./index.php?lvl=notice_display&id=31028

The effect of risperidone treatment on superoxide dismutase in schizophrenia / Xiang Yang Zhang en Journal of Clinical Psychopharmacology, Año 2003 - Vol. 23 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 2 (Abril) . - pp. 128-131 Título : The effect of risperidone treatment on superoxide dismutase in schizophrenia Tipo de documento: texto impreso Autores: Xiang Yang Zhang, Autor ; Dong Feng Zhou, Autor ; Lian Yuan Cao, Autor Fecha de publicación: 2023 Artículo en la página: pp. 128-131 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Radioinmunoensayo, Risperidona, Esquizofrenia, Superóxido dismutasa. Resumen: Some reports have shown that schizophrenia is accompanied by the abnormal metabolism of free radicals. The purpose of this study was to investigate the effect of the atypical antipsychotic drug risperidone on blood superoxide dismutase (SOD), a critical enzyme in the detoxification of superoxide radicals, and to explore the relationship between changes in SOD and the therapeutic outcome. Link: ./index.php?lvl=notice_display&id=31029 [artículo] The effect of risperidone treatment on superoxide dismutase in schizophrenia [texto impreso] / Xiang Yang Zhang, Autor ; Dong Feng Zhou, Autor ; Lian Yuan Cao, Autor . - 2023 . - pp. 128-131. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 2 (Abril) . - pp. 128-131 Palabras clave: Antipsicóticos, Radioinmunoensayo, Risperidona, Esquizofrenia, Superóxido dismutasa. Resumen: Some reports have shown that schizophrenia is accompanied by the abnormal metabolism of free radicals. The purpose of this study was to investigate the effect of the atypical antipsychotic drug risperidone on blood superoxide dismutase (SOD), a critical enzyme in the detoxification of superoxide radicals, and to explore the relationship between changes in SOD and the therapeutic outcome. Link: ./index.php?lvl=notice_display&id=31029

Acute dysphoric mania: treatment response to olanzapine versus placebo / Mauricio Tohen ; Jan Fawcett en Journal of Clinical Psychopharmacology, Año 2003 - Vol. 23 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 2 (Abril) . - pp. 132-137 Título : Acute dysphoric mania: treatment response to olanzapine versus placebo Tipo de documento: texto impreso Autores: Mauricio Tohen, Autor ; Jan Fawcett, Autor Fecha de publicación: 2023 Artículo en la página: pp. 132-137 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Enfermedad aguda, Afecto, Antipsicóticos, Benzodiazepinas, Trastorno Bipolar, Pirenzepina. Resumen: A substantial number of patients with mania have significant concomitant depressive features, and they may respond differently to mood stabilizers than patients with pure mania. This post-hoc analysis explored the response characteristics of olanzapine versus placebo in bipolar I manic patients with dysphoric and nondysphoric mania (differentiated by baseline Hamilton Depression Rating Scale [HAM-D] score of >20). Link: ./index.php?lvl=notice_display&id=31030 [artículo] Acute dysphoric mania: treatment response to olanzapine versus placebo [texto impreso] / Mauricio Tohen, Autor ; Jan Fawcett, Autor . - 2023 . - pp. 132-137. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 2 (Abril) . - pp. 132-137 Palabras clave: Enfermedad aguda, Afecto, Antipsicóticos, Benzodiazepinas, Trastorno Bipolar, Pirenzepina. Resumen: A substantial number of patients with mania have significant concomitant depressive features, and they may respond differently to mood stabilizers than patients with pure mania. This post-hoc analysis explored the response characteristics of olanzapine versus placebo in bipolar I manic patients with dysphoric and nondysphoric mania (differentiated by baseline Hamilton Depression Rating Scale [HAM-D] score of >20). Link: ./index.php?lvl=notice_display&id=31030

Initial platelet serotonin (5-ht) transport kinetics predict nortriptyline treatment outcome / Jeffrey L. Rausch en Journal of Clinical Psychopharmacology, Año 2003 - Vol. 23 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 2 (Abril) . - pp. 138-144 Título : Initial platelet serotonin (5-ht) transport kinetics predict nortriptyline treatment outcome Tipo de documento: texto impreso Autores: Jeffrey L. Rausch, Autor ; Frederick G. Moeller, Autor ; Maria E. Johnson, Autor Fecha de publicación: 2023 Artículo en la página: pp. 138-144 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antidepresivos tricíclicos, Biomarcadores, Plaquetas sanguíneas, Trastorno Depresivo, Glicoproteínas, Nortriptilina, Serotonina. Resumen: According to the hypothesis of initial conditions, drug response may be determined by different initial states of neurotransmitter protein recognition systems. Platelet serotonin (5-HT) transport kinetics were studied as initial-conditions predictors of antidepressant response in 24 depressed patients before and after 3 weeks of treatment with nortriptyline (75 mg). Link: ./index.php?lvl=notice_display&id=31031 [artículo] Initial platelet serotonin (5-ht) transport kinetics predict nortriptyline treatment outcome [texto impreso] / Jeffrey L. Rausch, Autor ; Frederick G. Moeller, Autor ; Maria E. Johnson, Autor . - 2023 . - pp. 138-144. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 2 (Abril) . - pp. 138-144 Palabras clave: Antidepresivos tricíclicos, Biomarcadores, Plaquetas sanguíneas, Trastorno Depresivo, Glicoproteínas, Nortriptilina, Serotonina. Resumen: According to the hypothesis of initial conditions, drug response may be determined by different initial states of neurotransmitter protein recognition systems. Platelet serotonin (5-HT) transport kinetics were studied as initial-conditions predictors of antidepressant response in 24 depressed patients before and after 3 weeks of treatment with nortriptyline (75 mg). Link: ./index.php?lvl=notice_display&id=31031

Economic evaluation of antidepressive agents: a systematic critique of experimental and observational studies / Corrado Barbui en Journal of Clinical Psychopharmacology, Año 2003 - Vol. 23 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 2 (Abril) . - pp. 145-154 Título : Economic evaluation of antidepressive agents: a systematic critique of experimental and observational studies Tipo de documento: texto impreso Autores: Corrado Barbui, Autor ; Mauro Percudani, Autor ; Matthew Hotopf, Autor Fecha de publicación: 2023 Artículo en la página: pp. 145-154 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antidepresivos, Trastorno depresivo, Economía, Costos de atención médica, Inhibidores selectivos de la recaptación de serotonina. Resumen: The purpose of this study was to examine whether experimental and observational pharmacoeconomic analyses of antidepressant drugs support the choice of one of the selective serotonin reuptake inhibitors or newer antidepressants as first-line treatment for patients with major depression. Link: ./index.php?lvl=notice_display&id=31032 [artículo] Economic evaluation of antidepressive agents: a systematic critique of experimental and observational studies [texto impreso] / Corrado Barbui, Autor ; Mauro Percudani, Autor ; Matthew Hotopf, Autor . - 2023 . - pp. 145-154. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 2 (Abril) . - pp. 145-154 Palabras clave: Antidepresivos, Trastorno depresivo, Economía, Costos de atención médica, Inhibidores selectivos de la recaptación de serotonina. Resumen: The purpose of this study was to examine whether experimental and observational pharmacoeconomic analyses of antidepressant drugs support the choice of one of the selective serotonin reuptake inhibitors or newer antidepressants as first-line treatment for patients with major depression. Link: ./index.php?lvl=notice_display&id=31032

Clinical and neurobiological effects of tianeptine and paroxetine in major depression / Thomas Nickel en Journal of Clinical Psychopharmacology, Año 2003 - Vol. 23 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 2 (Abril) . - pp. 155-168 Título : Clinical and neurobiological effects of tianeptine and paroxetine in major depression Tipo de documento: texto impreso Autores: Thomas Nickel, Autor ; Annette Sonntag, Autor ; Julia Schill, Autor Fecha de publicación: 2023 Artículo en la página: pp. 155-168 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antidepresivos tricíclicos, Cognición, Trastorno depresivo mayor, Pruebas neuropsicológicas. Resumen: Selective serotonin reuptake inhibitors (SSRIs) are widely used as effective pharmacological agents to treat depressive disorders. In contrast to the SSRIs, which block the presynaptic serotonin (5-HT) transporter and by this route increase the concentration of serotonin in the synaptic cleft, the antidepressant tianeptine enhances the presynaptic neuronal reuptake of 5-HT and thus decreases serotonergic neurotransmission. Link: ./index.php?lvl=notice_display&id=31033 [artículo] Clinical and neurobiological effects of tianeptine and paroxetine in major depression [texto impreso] / Thomas Nickel, Autor ; Annette Sonntag, Autor ; Julia Schill, Autor . - 2023 . - pp. 155-168. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 2 (Abril) . - pp. 155-168 Palabras clave: Antidepresivos tricíclicos, Cognición, Trastorno depresivo mayor, Pruebas neuropsicológicas. Resumen: Selective serotonin reuptake inhibitors (SSRIs) are widely used as effective pharmacological agents to treat depressive disorders. In contrast to the SSRIs, which block the presynaptic serotonin (5-HT) transporter and by this route increase the concentration of serotonin in the synaptic cleft, the antidepressant tianeptine enhances the presynaptic neuronal reuptake of 5-HT and thus decreases serotonergic neurotransmission. Link: ./index.php?lvl=notice_display&id=31033

The role of cytochrome p450 2c19 activity in flunitrazepam metabolism in vivo / Inbal Gafni M. en Journal of Clinical Psychopharmacology, Año 2003 - Vol. 23 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 2 (Abril) . - pp. 169-175 Título : The role of cytochrome p450 2c19 activity in flunitrazepam metabolism in vivo Tipo de documento: texto impreso Autores: Inbal Gafni M., Autor ; Usoa E. Busto, Autor ; Rachel F. Tyndale, Autor Fecha de publicación: 2023 Artículo en la página: pp. 169-175 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Ansiolíticos, Cromatografía líquida, Citocromo P-450 CYP2C19, Flunitrazepam. Resumen: Flunitrazepam, a hypnotic benzodiazepine, is widely prescribed around the world for the treatment of insomnia and as a preanesthetic. In vitro studies have shown that the metabolism of flunitrazepam to desmethylflunitrazepam and 3-hydroxyflunitrazepam is mediated in part by the polymorphic enzyme CYP2C19. The objective was to examine the role of CYP2C19 activity in determining flunitrazepam kinetics in vivo. Link: ./index.php?lvl=notice_display&id=31034 [artículo] The role of cytochrome p450 2c19 activity in flunitrazepam metabolism in vivo [texto impreso] / Inbal Gafni M., Autor ; Usoa E. Busto, Autor ; Rachel F. Tyndale, Autor . - 2023 . - pp. 169-175. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 2 (Abril) . - pp. 169-175 Palabras clave: Ansiolíticos, Cromatografía líquida, Citocromo P-450 CYP2C19, Flunitrazepam. Resumen: Flunitrazepam, a hypnotic benzodiazepine, is widely prescribed around the world for the treatment of insomnia and as a preanesthetic. In vitro studies have shown that the metabolism of flunitrazepam to desmethylflunitrazepam and 3-hydroxyflunitrazepam is mediated in part by the polymorphic enzyme CYP2C19. The objective was to examine the role of CYP2C19 activity in determining flunitrazepam kinetics in vivo. Link: ./index.php?lvl=notice_display&id=31034

Safety and efficacy of switching psychiatric patients from a delayed-release to an extended-release formulation of divalproex sodium / Robert Lynn Horne en Journal of Clinical Psychopharmacology, Año 2003 - Vol. 23 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 2 (Abril) . - pp. 176-181 Título : Safety and efficacy of switching psychiatric patients from a delayed-release to an extended-release formulation of divalproex sodium Tipo de documento: texto impreso Autores: Robert Lynn Horne, Autor ; Cedric Cunanan, Autor Fecha de publicación: 2023 Artículo en la página: pp. 176-181 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antimaníacos, Trastornos mentales - diagnóstico, Acido Valproico. Resumen: This study evaluated the safety and efficacy of divalproex sodium extended-release (ER) when patients were switched from therapy with divalproex sodium delayed-release (DR) to divalproex sodium ER. This open-label, 7-day study included 55 patients with bipolar disorder, major depression, schizophrenia, schizoaffective disorder, Alzheimer’s disease, dementia, or intermittent explosive disorder. Link: ./index.php?lvl=notice_display&id=31035 [artículo] Safety and efficacy of switching psychiatric patients from a delayed-release to an extended-release formulation of divalproex sodium [texto impreso] / Robert Lynn Horne, Autor ; Cedric Cunanan, Autor . - 2023 . - pp. 176-181. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 2 (Abril) . - pp. 176-181 Palabras clave: Antimaníacos, Trastornos mentales - diagnóstico, Acido Valproico. Resumen: This study evaluated the safety and efficacy of divalproex sodium extended-release (ER) when patients were switched from therapy with divalproex sodium delayed-release (DR) to divalproex sodium ER. This open-label, 7-day study included 55 patients with bipolar disorder, major depression, schizophrenia, schizoaffective disorder, Alzheimer’s disease, dementia, or intermittent explosive disorder. Link: ./index.php?lvl=notice_display&id=31035

Antidepressant properties of anticonvulsant drugs for bipolar disorder / Carrie L Ernst en Journal of Clinical Psychopharmacology, Año 2003 - Vol. 23 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 2 (Abril) . - pp. 182-192 Título : Antidepressant properties of anticonvulsant drugs for bipolar disorder Tipo de documento: texto impreso Autores: Carrie L Ernst, Autor ; Joseph F. Goldberg, Autor Fecha de publicación: 2023 Artículo en la página: pp. 182-192 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Afecto, Aminas, Anticonvulsivos, Antidepresivos, Trastorno bipolar, Ácidos ciclohexanocarboxílicos, Gabapentina, Litio. Resumen: A growing number of anticonvulsant drugs are receiving attention as possible mood stabilizers. This attention is based mainly on the assumption that the antimanic efficacy of anticonvulsants makes them suitable as mood stabilizers. However, their antidepressant properties have received less scrutiny. Link: ./index.php?lvl=notice_display&id=31036 [artículo] Antidepressant properties of anticonvulsant drugs for bipolar disorder [texto impreso] / Carrie L Ernst, Autor ; Joseph F. Goldberg, Autor . - 2023 . - pp. 182-192. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2003 - Vol. 23 - No. 2 (Abril) . - pp. 182-192 Palabras clave: Afecto, Aminas, Anticonvulsivos, Antidepresivos, Trastorno bipolar, Ácidos ciclohexanocarboxílicos, Gabapentina, Litio. Resumen: A growing number of anticonvulsant drugs are receiving attention as possible mood stabilizers. This attention is based mainly on the assumption that the antimanic efficacy of anticonvulsants makes them suitable as mood stabilizers. However, their antidepressant properties have received less scrutiny. Link: ./index.php?lvl=notice_display&id=31036