Artículos

Are lorazepam-induced deficits in attention similar to those resulting from aging? / Emma Fluck en Journal of Clinical Psychopharmacology, Año 2001 - Vol. 21 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 126-130 Título : Are lorazepam-induced deficits in attention similar to those resulting from aging? Tipo de documento: texto impreso Autores: Emma Fluck, Autor ; Cathy Fernandes, Autor ; Sandra E. File, Autor Fecha de publicación: 2023 Artículo en la página: pp. 126-130 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Envejecimiento, Atención, Moduladores GABA, Lorazepam. Resumen: The purpose of this experiment was to compare, in three tasks of attention, the impairment caused by lorazepam (1 and 2.5 mg) administered to young volunteers with the impairment that results from aging. Performance on digit cancellation (DC), digit-symbol substitution (DSS), and Paced Auditory Serial Addition Task (PASAT) was significantly impaired by lorazepam (2.5 mg) and was significantly worse in the middle-aged group (mean ± SEM, aged 58.9 ± 0.8 years) compared with the younger, IQ-matched group (20.7 ± 0.2 years). Link: ./index.php?lvl=notice_display&id=31115 [artículo] Are lorazepam-induced deficits in attention similar to those resulting from aging? [texto impreso] / Emma Fluck, Autor ; Cathy Fernandes, Autor ; Sandra E. File, Autor . - 2023 . - pp. 126-130. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 126-130 Palabras clave: Envejecimiento, Atención, Moduladores GABA, Lorazepam. Resumen: The purpose of this experiment was to compare, in three tasks of attention, the impairment caused by lorazepam (1 and 2.5 mg) administered to young volunteers with the impairment that results from aging. Performance on digit cancellation (DC), digit-symbol substitution (DSS), and Paced Auditory Serial Addition Task (PASAT) was significantly impaired by lorazepam (2.5 mg) and was significantly worse in the middle-aged group (mean ± SEM, aged 58.9 ± 0.8 years) compared with the younger, IQ-matched group (20.7 ± 0.2 years). Link: ./index.php?lvl=notice_display&id=31115

Absence of neuropsychologic deficits in patients receiving long-term treatment with alprazolam-xr for panic disorder / Julie Akiko Gladsjo en Journal of Clinical Psychopharmacology, Año 2001 - Vol. 21 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 131-138 Título : Absence of neuropsychologic deficits in patients receiving long-term treatment with alprazolam-xr for panic disorder Tipo de documento: texto impreso Autores: Julie Akiko Gladsjo, Autor ; Mark H. Rapaport, Autor ; Rebecca McKinney, Autor Fecha de publicación: 2023 Artículo en la página: pp. 131-138 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Alprazolam, Agentes ansiolíticos, Trastornos de la memoria, Pruebas Neuropsicológicas, Trastorno de pánico. Resumen: Studies to date on the effects of benzodiazepines on neuropsychologic function have yielded conflicting data with respect to the type, severity, and duration of deficits that may be induced by these agents. As part of a placebo-controlled trial of alprazolam-XR (extended release) administered in combination with cognitive-behavioral therapy in patients with panic disorder, a battery of tests was used to measure neuropsychologic function. Link: ./index.php?lvl=notice_display&id=31116 [artículo] Absence of neuropsychologic deficits in patients receiving long-term treatment with alprazolam-xr for panic disorder [texto impreso] / Julie Akiko Gladsjo, Autor ; Mark H. Rapaport, Autor ; Rebecca McKinney, Autor . - 2023 . - pp. 131-138. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 131-138 Palabras clave: Alprazolam, Agentes ansiolíticos, Trastornos de la memoria, Pruebas Neuropsicológicas, Trastorno de pánico. Resumen: Studies to date on the effects of benzodiazepines on neuropsychologic function have yielded conflicting data with respect to the type, severity, and duration of deficits that may be induced by these agents. As part of a placebo-controlled trial of alprazolam-XR (extended release) administered in combination with cognitive-behavioral therapy in patients with panic disorder, a battery of tests was used to measure neuropsychologic function. Link: ./index.php?lvl=notice_display&id=31116

Fluvoxamine treatment of mixed anxiety and depression: evidence for serotonergically mediated anxiolysis / Jeffrey L. Rausch en Journal of Clinical Psychopharmacology, Año 2001 - Vol. 21 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 139-142 Título : Fluvoxamine treatment of mixed anxiety and depression: evidence for serotonergically mediated anxiolysis Tipo de documento: texto impreso Autores: Jeffrey L. Rausch, Autor ; H. Mac Hobby, Autor ; Nitin Shendarkar, Autor Fecha de publicación: 2023 Artículo en la página: pp. 139-142 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastornos de ansiedad, Trastorno depresivo mayor, Fluvoxamina, Inhibidores selectivos de la recaptación de serotonina. Link: ./index.php?lvl=notice_display&id=31117 [artículo] Fluvoxamine treatment of mixed anxiety and depression: evidence for serotonergically mediated anxiolysis [texto impreso] / Jeffrey L. Rausch, Autor ; H. Mac Hobby, Autor ; Nitin Shendarkar, Autor . - 2023 . - pp. 139-142. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 139-142 Palabras clave: Trastornos de ansiedad, Trastorno depresivo mayor, Fluvoxamina, Inhibidores selectivos de la recaptación de serotonina. Link: ./index.php?lvl=notice_display&id=31117

Double-blind clinical trial of sertraline treatment for alcohol dependence / Helen Pettinati en Journal of Clinical Psychopharmacology, Año 2001 - Vol. 21 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 143-153 Título : Double-blind clinical trial of sertraline treatment for alcohol dependence Tipo de documento: texto impreso Autores: Helen Pettinati, Autor ; Joseph R. Volpicelli, Autor ; Gary Luck, Autor Fecha de publicación: 2023 Artículo en la página: pp. 143-153 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Alcoholismo, Trastorno depresivo, Diagnóstico Dual, Inhibidores selectivos de la recaptación de serotonina. Resumen: Clinical studies that have evaluated serotonergic medications to reduce alcohol consumption have yielded conflicting results. These studies primarily treated patients with alcohol dependence, excluding those with a current depressive disorder, in an effort to differentiate any medication effects directly on drinking from those on mood. Link: ./index.php?lvl=notice_display&id=31118 [artículo] Double-blind clinical trial of sertraline treatment for alcohol dependence [texto impreso] / Helen Pettinati, Autor ; Joseph R. Volpicelli, Autor ; Gary Luck, Autor . - 2023 . - pp. 143-153. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 143-153 Palabras clave: Alcoholismo, Trastorno depresivo, Diagnóstico Dual, Inhibidores selectivos de la recaptación de serotonina. Resumen: Clinical studies that have evaluated serotonergic medications to reduce alcohol consumption have yielded conflicting results. These studies primarily treated patients with alcohol dependence, excluding those with a current depressive disorder, in an effort to differentiate any medication effects directly on drinking from those on mood. Link: ./index.php?lvl=notice_display&id=31118

Effect on sexual function of long-term treatment with selective serotonin reuptake inhibitors in depressed patients treated in primary care / Lisa Ekselius en Journal of Clinical Psychopharmacology, Año 2001 - Vol. 21 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 154-160 Título : Effect on sexual function of long-term treatment with selective serotonin reuptake inhibitors in depressed patients treated in primary care Tipo de documento: texto impreso Autores: Lisa Ekselius, Autor ; Lars von Knorring, Autor Fecha de publicación: 2023 Artículo en la página: pp. 154-160 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastorno depresivo mayor, Primeros auxilios, Inhibidores selectivos de la recaptación de serotonina, Sertralina, Disfunciones Sexuales. Resumen: The purpose of this study was to prospectively examine the occurrence and severity of sexual dysfunction symptoms in depressed patients before and after 6 months of treatment with selective serotonin reuptake inhibitors. The study was part of a randomized, double-blind, controlled trial of sertraline or citalopram in patients with a DSM-III-R major depressive disorder treated by general practitioners. Link: ./index.php?lvl=notice_display&id=31119 [artículo] Effect on sexual function of long-term treatment with selective serotonin reuptake inhibitors in depressed patients treated in primary care [texto impreso] / Lisa Ekselius, Autor ; Lars von Knorring, Autor . - 2023 . - pp. 154-160. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 154-160 Palabras clave: Trastorno depresivo mayor, Primeros auxilios, Inhibidores selectivos de la recaptación de serotonina, Sertralina, Disfunciones Sexuales. Resumen: The purpose of this study was to prospectively examine the occurrence and severity of sexual dysfunction symptoms in depressed patients before and after 6 months of treatment with selective serotonin reuptake inhibitors. The study was part of a randomized, double-blind, controlled trial of sertraline or citalopram in patients with a DSM-III-R major depressive disorder treated by general practitioners. Link: ./index.php?lvl=notice_display&id=31119

Fluoxetine pharmacokinetics and effect on cyp2c19 in young and elderly volunteers / Anne T. Harvey en Journal of Clinical Psychopharmacology, Año 2001 - Vol. 21 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 161-166 Título : Fluoxetine pharmacokinetics and effect on cyp2c19 in young and elderly volunteers Tipo de documento: texto impreso Autores: Anne T. Harvey, Autor ; Sheldon H. Preskorn, Autor Fecha de publicación: 2023 Artículo en la página: pp. 161-166 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Citocromo P-450 CYP2C19, Sistema enzimático citocromo P-450, Fluoxetina, Oxigenasas de función mixta, Inhibidores selectivos de la recaptación de serotonina. Resumen: The objective of this study was to assess in both young and elderly volunteers the pharmacokinetics of fluoxetine and norfluoxetine and effects on cytochrome P450 (CYP) 2C19. Male volunteers aged 18 to 40 years (N = 14) or older than 65 years (N = 16) received fluoxetine 20 mg/day for 6 weeks and fluoxetine 40 mg/day for an additional 6 weeks. Link: ./index.php?lvl=notice_display&id=31120 [artículo] Fluoxetine pharmacokinetics and effect on cyp2c19 in young and elderly volunteers [texto impreso] / Anne T. Harvey, Autor ; Sheldon H. Preskorn, Autor . - 2023 . - pp. 161-166. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 161-166 Palabras clave: Citocromo P-450 CYP2C19, Sistema enzimático citocromo P-450, Fluoxetina, Oxigenasas de función mixta, Inhibidores selectivos de la recaptación de serotonina. Resumen: The objective of this study was to assess in both young and elderly volunteers the pharmacokinetics of fluoxetine and norfluoxetine and effects on cytochrome P450 (CYP) 2C19. Male volunteers aged 18 to 40 years (N = 14) or older than 65 years (N = 16) received fluoxetine 20 mg/day for 6 weeks and fluoxetine 40 mg/day for an additional 6 weeks. Link: ./index.php?lvl=notice_display&id=31120

Differential effects of fluvoxamine and other antidepressants on the biotransformation of melatonin / Sebastian Härtter en Journal of Clinical Psychopharmacology, Año 2001 - Vol. 21 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 167-174 Título : Differential effects of fluvoxamine and other antidepressants on the biotransformation of melatonin Tipo de documento: texto impreso Autores: Sebastian Härtter, Autor ; Ximing Wang, Autor ; Harald Weigmann, Autor Fecha de publicación: 2023 Artículo en la página: pp. 167-174 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Citocromo P-450 CYP1A2, Fluvoxamina, Melatonina, Microsomas, Serotonina, Teofilina. Resumen: Melatonin, the predominant product of the pineal gland, is involved in the maintenance of diurnal. rhythms. Nocturnal blood concentrations of melatonin have been shown to be enhanced by fluvoxamine, but not by other serotonin reuptake inhibitors. Because fluvoxamine is an inhibitor of several cytochrome P450 (CYP) enzymes, the authors studied the biotransformation of melatonin and the effects of fluvoxamine on the metabolism of melatonin in vitro using human liver microsomes and recombinant human CYP isoenzymes. Link: ./index.php?lvl=notice_display&id=31121 [artículo] Differential effects of fluvoxamine and other antidepressants on the biotransformation of melatonin [texto impreso] / Sebastian Härtter, Autor ; Ximing Wang, Autor ; Harald Weigmann, Autor . - 2023 . - pp. 167-174. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 167-174 Palabras clave: Citocromo P-450 CYP1A2, Fluvoxamina, Melatonina, Microsomas, Serotonina, Teofilina. Resumen: Melatonin, the predominant product of the pineal gland, is involved in the maintenance of diurnal. rhythms. Nocturnal blood concentrations of melatonin have been shown to be enhanced by fluvoxamine, but not by other serotonin reuptake inhibitors. Because fluvoxamine is an inhibitor of several cytochrome P450 (CYP) enzymes, the authors studied the biotransformation of melatonin and the effects of fluvoxamine on the metabolism of melatonin in vitro using human liver microsomes and recombinant human CYP isoenzymes. Link: ./index.php?lvl=notice_display&id=31121

Diphenhydramine alters the disposition of venlafaxine through inhibition of cyp2d6 activity in humans / Étienne Lessard en Journal of Clinical Psychopharmacology, Año 2001 - Vol. 21 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 175-184 Título : Diphenhydramine alters the disposition of venlafaxine through inhibition of cyp2d6 activity in humans Tipo de documento: texto impreso Autores: Étienne Lessard, Autor ; Marie Andrée Yessine, Autor ; Bettina A. Hamelin, Autor Fecha de publicación: 2023 Artículo en la página: pp. 175-184 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antidepresivos, Ciclohexanoles, Citocromo P-450 CYP2D6, Difenhidramina, Interacción medicamentosa. Resumen: CYP2D6 is the major enzyme involved in the metabolism of venlafaxine. Subjects with a low CYP2D6 activity have increased plasma concentrations of venlafaxine that may predispose them to cardiovascular side effects. In vitro and in vivo studies showed that diphenhydramine, a nonprescription antihistamine, can inhibit CYP2D6 activity. Therefore, the authors investigated in this study a potential drug interaction between diphenhydramine and venlafaxine. Link: ./index.php?lvl=notice_display&id=31122 [artículo] Diphenhydramine alters the disposition of venlafaxine through inhibition of cyp2d6 activity in humans [texto impreso] / Étienne Lessard, Autor ; Marie Andrée Yessine, Autor ; Bettina A. Hamelin, Autor . - 2023 . - pp. 175-184. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 175-184 Palabras clave: Antidepresivos, Ciclohexanoles, Citocromo P-450 CYP2D6, Difenhidramina, Interacción medicamentosa. Resumen: CYP2D6 is the major enzyme involved in the metabolism of venlafaxine. Subjects with a low CYP2D6 activity have increased plasma concentrations of venlafaxine that may predispose them to cardiovascular side effects. In vitro and in vivo studies showed that diphenhydramine, a nonprescription antihistamine, can inhibit CYP2D6 activity. Therefore, the authors investigated in this study a potential drug interaction between diphenhydramine and venlafaxine. Link: ./index.php?lvl=notice_display&id=31122

Sustained response to open-label venlafaxine in drug-resistant major depression / Isaac Schweitzer en Journal of Clinical Psychopharmacology, Año 2001 - Vol. 21 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 185-189 Título : Sustained response to open-label venlafaxine in drug-resistant major depression Tipo de documento: texto impreso Autores: Isaac Schweitzer, Autor ; Graham AO, Burrows, Autor ; Virginia Tuckwell, Autor Fecha de publicación: 2023 Artículo en la página: pp. 185-189 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antidepresivos de segunda generación, Ciclohexanoles, Trastorno depresivo mayor, Resistencia a los medicamentos. Resumen: The aim of this study was to evaluate the response to venlafaxine in patients with treatment-resistant depression during an extension phase of an open-label study of venlafaxine. After completing the initial 8 weeks of the study, patients could continue venlafaxine treatment for an additional period of up to 10 months. Efficacy results are given for 149 patients with treatment-resistant depression. Link: ./index.php?lvl=notice_display&id=31123 [artículo] Sustained response to open-label venlafaxine in drug-resistant major depression [texto impreso] / Isaac Schweitzer, Autor ; Graham AO, Burrows, Autor ; Virginia Tuckwell, Autor . - 2023 . - pp. 185-189. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 185-189 Palabras clave: Antidepresivos de segunda generación, Ciclohexanoles, Trastorno depresivo mayor, Resistencia a los medicamentos. Resumen: The aim of this study was to evaluate the response to venlafaxine in patients with treatment-resistant depression during an extension phase of an open-label study of venlafaxine. After completing the initial 8 weeks of the study, patients could continue venlafaxine treatment for an additional period of up to 10 months. Efficacy results are given for 149 patients with treatment-resistant depression. Link: ./index.php?lvl=notice_display&id=31123

Changes in quantitatively assessed tremor during treatment of major depression with lithium augmented by paroxetine or amitriptyline / Rocco Zaninelli en Journal of Clinical Psychopharmacology, Año 2001 - Vol. 21 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 190-198 Título : Changes in quantitatively assessed tremor during treatment of major depression with lithium augmented by paroxetine or amitriptyline Tipo de documento: texto impreso Autores: Rocco Zaninelli, Autor ; Michael Bauer, Autor ; Marc Jobert, Autor Fecha de publicación: 2023 Artículo en la página: pp. 190-198 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Amitriptilina, Antidepresivos, Antimaníacos, Trastorno depresivo mayor, Farmacoterapia, Cloruro de Litio, Paroxetina, Temblor. Resumen: Tremor is a relatively frequent side effect of lithium and of antidepressants with serotonergic properties. It can be expected that combinations of lithium (which is itself serotonergic) with such antidepressants will enhance not only efficacy, but also the incidence of side effects, including tremor. Link: ./index.php?lvl=notice_display&id=31124 [artículo] Changes in quantitatively assessed tremor during treatment of major depression with lithium augmented by paroxetine or amitriptyline [texto impreso] / Rocco Zaninelli, Autor ; Michael Bauer, Autor ; Marc Jobert, Autor . - 2023 . - pp. 190-198. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 190-198 Palabras clave: Amitriptilina, Antidepresivos, Antimaníacos, Trastorno depresivo mayor, Farmacoterapia, Cloruro de Litio, Paroxetina, Temblor. Resumen: Tremor is a relatively frequent side effect of lithium and of antidepressants with serotonergic properties. It can be expected that combinations of lithium (which is itself serotonergic) with such antidepressants will enhance not only efficacy, but also the incidence of side effects, including tremor. Link: ./index.php?lvl=notice_display&id=31124

Anti-inflammatory effects of antidepressants through suppression of the interferon-γ/interleukin-10 production ratio / Marta Kubera en Journal of Clinical Psychopharmacology, Año 2001 - Vol. 21 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 199-206 Título : Anti-inflammatory effects of antidepressants through suppression of the interferon-γ/interleukin-10 production ratio Tipo de documento: texto impreso Autores: Marta Kubera, Autor ; Ai-Hua Lin, Autor ; Günter R.L. Kenis, Autor Fecha de publicación: 2023 Artículo en la página: pp. 199-206 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antidepresivos, Trastorno depresivo, Fluoxetina, Imipramina, Interferón gamma. Resumen: There is some evidence that major depression-in particular, treatment-resistant depression (TRD)-is accompanied by activation of the inflammatory response system and that proinflammatory cytokines may play a role in the etiology of depression. This study was carried out to examine the effects of antidepressive agents, i.e., imipramine, venlafaxine, L-5-hydroxytryptophan, and fluoxetine on the production of interferon-γ (IFN-γ), a proinflammatory cytokine, and interleukin-10 (IL-10), a negative immunoregulatory cytokine. Link: ./index.php?lvl=notice_display&id=31125 [artículo] Anti-inflammatory effects of antidepressants through suppression of the interferon-γ/interleukin-10 production ratio [texto impreso] / Marta Kubera, Autor ; Ai-Hua Lin, Autor ; Günter R.L. Kenis, Autor . - 2023 . - pp. 199-206. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 199-206 Palabras clave: Antidepresivos, Trastorno depresivo, Fluoxetina, Imipramina, Interferón gamma. Resumen: There is some evidence that major depression-in particular, treatment-resistant depression (TRD)-is accompanied by activation of the inflammatory response system and that proinflammatory cytokines may play a role in the etiology of depression. This study was carried out to examine the effects of antidepressive agents, i.e., imipramine, venlafaxine, L-5-hydroxytryptophan, and fluoxetine on the production of interferon-γ (IFN-γ), a proinflammatory cytokine, and interleukin-10 (IL-10), a negative immunoregulatory cytokine. Link: ./index.php?lvl=notice_display&id=31125

In vivo extrastriatal and striatal d2 dopamine receptor blockade by amisulpride in schizophrenia / Xavier Xiberas en Journal of Clinical Psychopharmacology, Año 2001 - Vol. 21 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 207-214 Título : In vivo extrastriatal and striatal d2 dopamine receptor blockade by amisulpride in schizophrenia Tipo de documento: texto impreso Autores: Xavier Xiberas, Autor ; Jean Luc Martinot, Autor ; Luc Mallet, Autor Fecha de publicación: 2023 Artículo en la página: pp. 207-214 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Esquizofrenia, Sulpirida, Tálamo. Resumen: Amisulpride, a substituted benzamide with high affinity for dopamine D2 and D3 receptors only, has been reported to have therapeutic effects on both negative and positive schizophrenic symptoms, although at distinct dose ranges (50-300 mg/day vs. 400-1,200 mg/day). Link: ./index.php?lvl=notice_display&id=31126 [artículo] In vivo extrastriatal and striatal d2 dopamine receptor blockade by amisulpride in schizophrenia [texto impreso] / Xavier Xiberas, Autor ; Jean Luc Martinot, Autor ; Luc Mallet, Autor . - 2023 . - pp. 207-214. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 207-214 Palabras clave: Antipsicóticos, Esquizofrenia, Sulpirida, Tálamo. Resumen: Amisulpride, a substituted benzamide with high affinity for dopamine D2 and D3 receptors only, has been reported to have therapeutic effects on both negative and positive schizophrenic symptoms, although at distinct dose ranges (50-300 mg/day vs. 400-1,200 mg/day). Link: ./index.php?lvl=notice_display&id=31126

Relevance of liver enzyme elevations with four different neuroleptics: a retrospective review of 7,263 treatment courses / Ines Gaertner en Journal of Clinical Psychopharmacology, Año 2001 - Vol. 21 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 215-222 Título : Relevance of liver enzyme elevations with four different neuroleptics: a retrospective review of 7,263 treatment courses Tipo de documento: texto impreso Autores: Ines Gaertner, Autor ; Kristin Altendorf, Autor ; Anil Batra, Autor Fecha de publicación: 2023 Artículo en la página: pp. 215-222 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Aspartato Aminotransferasas, Clozapina, Glutamato Deshidrogenasa, Haloperidol, Perazina, Perfenazina, Esquizofrenia. Resumen: Data on liver enzyme elevations were collected in a retrospective study of 7,263 treatment courses with haloperidol, clozapine, perphenazine, and perazine. Charts of 233 patients hospitalized between 1980 and 1992 at Tübingen University Psychiatric Clinic were selected because clinically relevant increases of liver enzymes had been detected during monotherapy with one of the four examined neuroleptics. Link: ./index.php?lvl=notice_display&id=31127 [artículo] Relevance of liver enzyme elevations with four different neuroleptics: a retrospective review of 7,263 treatment courses [texto impreso] / Ines Gaertner, Autor ; Kristin Altendorf, Autor ; Anil Batra, Autor . - 2023 . - pp. 215-222. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 215-222 Palabras clave: Antipsicóticos, Aspartato Aminotransferasas, Clozapina, Glutamato Deshidrogenasa, Haloperidol, Perazina, Perfenazina, Esquizofrenia. Resumen: Data on liver enzyme elevations were collected in a retrospective study of 7,263 treatment courses with haloperidol, clozapine, perphenazine, and perazine. Charts of 233 patients hospitalized between 1980 and 1992 at Tübingen University Psychiatric Clinic were selected because clinically relevant increases of liver enzymes had been detected during monotherapy with one of the four examined neuroleptics. Link: ./index.php?lvl=notice_display&id=31127

Comparing guanfacine and dextroamphetamine for the treatment of adult attention-deficit/hyperactivity disorder / Fletcher B. Taylor en Journal of Clinical Psychopharmacology, Año 2001 - Vol. 21 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 223-228 Título : Comparing guanfacine and dextroamphetamine for the treatment of adult attention-deficit/hyperactivity disorder Tipo de documento: texto impreso Autores: Fletcher B. Taylor, Autor ; Joan E. Russo, Autor Fecha de publicación: 2023 Artículo en la página: pp. 223-228 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastorno por Déficit de Atención e Hiperactividad, Dextroanfetamina, Pruebas psicológicas. Resumen: The objective of this study was to compare the efficacy of the α-2a agonist guanfacine with that of dextroamphetamine for the treatment of adult attention-deficit/hyperactivity disorder (ADHD). Seventeen adult outpatients who met DSM-IV criteria for ADHD participated in a double-blind, placebo-controlled, crossover study comparing drug effects on ADHD symptoms. Link: ./index.php?lvl=notice_display&id=31128 [artículo] Comparing guanfacine and dextroamphetamine for the treatment of adult attention-deficit/hyperactivity disorder [texto impreso] / Fletcher B. Taylor, Autor ; Joan E. Russo, Autor . - 2023 . - pp. 223-228. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 223-228 Palabras clave: Trastorno por Déficit de Atención e Hiperactividad, Dextroanfetamina, Pruebas psicológicas. Resumen: The objective of this study was to compare the efficacy of the α-2a agonist guanfacine with that of dextroamphetamine for the treatment of adult attention-deficit/hyperactivity disorder (ADHD). Seventeen adult outpatients who met DSM-IV criteria for ADHD participated in a double-blind, placebo-controlled, crossover study comparing drug effects on ADHD symptoms. Link: ./index.php?lvl=notice_display&id=31128

Cytochrome p450 2d6 genotype and methadone steady-state concentrations / Chin B. Eap en Journal of Clinical Psychopharmacology, Año 2001 - Vol. 21 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 229-234 Título : Cytochrome p450 2d6 genotype and methadone steady-state concentrations Tipo de documento: texto impreso Autores: Chin B. Eap, Autor ; Franck Broly, Autor ; Annie Mino, Autor Fecha de publicación: 2023 Artículo en la página: pp. 229-234 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Citocromo P-450 CYP2D6, Metadona, Narcóticos, Estupefacientes - uso terapéutico, Trastornos relacionados con los opioides. Resumen: A genetic polymorphism of cytochrome P450 2D6 has been described with the existence of poor (zero functional genes), extensive (one or two functional genes), and ultrarapid metabolizers (three or more functional genes). The authors measured the steady-state trough (R)- (i.e., the active enantiomer), (S)-, and (R,S)-methadone plasma levels in opiate-dependent patients receiving methadone maintenance treatment (MMT) and genotyped them for cytochrome P4502D6. Link: ./index.php?lvl=notice_display&id=31129 [artículo] Cytochrome p450 2d6 genotype and methadone steady-state concentrations [texto impreso] / Chin B. Eap, Autor ; Franck Broly, Autor ; Annie Mino, Autor . - 2023 . - pp. 229-234. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 229-234 Palabras clave: Citocromo P-450 CYP2D6, Metadona, Narcóticos, Estupefacientes - uso terapéutico, Trastornos relacionados con los opioides. Resumen: A genetic polymorphism of cytochrome P450 2D6 has been described with the existence of poor (zero functional genes), extensive (one or two functional genes), and ultrarapid metabolizers (three or more functional genes). The authors measured the steady-state trough (R)- (i.e., the active enantiomer), (S)-, and (R,S)-methadone plasma levels in opiate-dependent patients receiving methadone maintenance treatment (MMT) and genotyped them for cytochrome P4502D6. Link: ./index.php?lvl=notice_display&id=31129