Artículos

Novel pharmacologic and other somatic treatment approaches for posttraumatic stress disorder in adults: state of the evidence / Lauren M. Sippel en The American Journal of Psychiatry, Año 2024 - Vol. 181 - No. 12 (Diciembre)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2024 - Vol. 181 - No. 12 (Diciembre) . - pp. 1045-1058 Título : Novel pharmacologic and other somatic treatment approaches for posttraumatic stress disorder in adults: state of the evidence Tipo de documento: texto impreso Autores: Lauren M. Sippel, Autor ; Jessica L. Hamblen, Autor ; Benjamín Kelmendi, Autor Fecha de publicación: 2025 Artículo en la página: pp. 1045-1058 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Psicoterapia conductual, Psicoterapia cognitiva, Combinación de psicoterapia farmacológica, Tratamiento basado en evidencia, Neuroestimulación, Farmacoterapia, Trastorno de estrés postraumático (TEPT), Psicoterapia. Resumen: Posttraumatic stress disorder (PTSD) is a highly prevalent psychiatric disorder that can become chronic and debilitating when left untreated. The most commonly recommended first-line treatments for PTSD among adults are individual trauma-focused psychotherapies. Other evidence-based treatments include specific antidepressant medications and non-trauma-focused psychotherapies. Link: ./index.php?lvl=notice_display&id=31518 [artículo] Novel pharmacologic and other somatic treatment approaches for posttraumatic stress disorder in adults: state of the evidence [texto impreso] / Lauren M. Sippel, Autor ; Jessica L. Hamblen, Autor ; Benjamín Kelmendi, Autor . - 2025 . - pp. 1045-1058. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2024 - Vol. 181 - No. 12 (Diciembre) . - pp. 1045-1058 Palabras clave: Psicoterapia conductual, Psicoterapia cognitiva, Combinación de psicoterapia farmacológica, Tratamiento basado en evidencia, Neuroestimulación, Farmacoterapia, Trastorno de estrés postraumático (TEPT), Psicoterapia. Resumen: Posttraumatic stress disorder (PTSD) is a highly prevalent psychiatric disorder that can become chronic and debilitating when left untreated. The most commonly recommended first-line treatments for PTSD among adults are individual trauma-focused psychotherapies. Other evidence-based treatments include specific antidepressant medications and non-trauma-focused psychotherapies. Link: ./index.php?lvl=notice_display&id=31518

An honest reckoning with the amygdala and mental illness / Andrew S. Fox en The American Journal of Psychiatry, Año 2024 - Vol. 181 - No. 12 (Diciembre)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2024 - Vol. 181 - No. 12 (Diciembre) . - pp. 1059-1075 Título : An honest reckoning with the amygdala and mental illness Tipo de documento: texto impreso Autores: Andrew S. Fox, Autor ; Alexander J. Shackman, Autor Fecha de publicación: 2025 Artículo en la página: pp. 1059-1075 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Neurociencia afectiva, Trastornos de ansiedad, Amígdala extendida, Miedo y ansiedad, Neuroanatomía. Resumen: Anxiety disorders are a leading source of human misery, morbidity, and premature mortality. Existing treatments are far from curative for many, underscoring the need to clarify the underlying neural mechanisms. Although many brain regions contribute, the amygdala has received the most intense scientific attention. Link: ./index.php?lvl=notice_display&id=31519 [artículo] An honest reckoning with the amygdala and mental illness [texto impreso] / Andrew S. Fox, Autor ; Alexander J. Shackman, Autor . - 2025 . - pp. 1059-1075. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2024 - Vol. 181 - No. 12 (Diciembre) . - pp. 1059-1075 Palabras clave: Neurociencia afectiva, Trastornos de ansiedad, Amígdala extendida, Miedo y ansiedad, Neuroanatomía. Resumen: Anxiety disorders are a leading source of human misery, morbidity, and premature mortality. Existing treatments are far from curative for many, underscoring the need to clarify the underlying neural mechanisms. Although many brain regions contribute, the amygdala has received the most intense scientific attention. Link: ./index.php?lvl=notice_display&id=31519

Resting-state functional connectivity of the amygdala in autism: a preregistered large-scale study / Dorit Kliemann en The American Journal of Psychiatry, Año 2024 - Vol. 181 - No. 12 (Diciembre)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2024 - Vol. 181 - No. 12 (Diciembre) . - pp. 1076-1085 Título : Resting-state functional connectivity of the amygdala in autism: a preregistered large-scale study Tipo de documento: texto impreso Autores: Dorit Kliemann, Autor ; Paola Galdi, Autor ; Avery L. Van De Water, Autor Fecha de publicación: 2025 Artículo en la página: pp. 1076-1085 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastorno del espectro autista, Neurociencia cognitiva, Conectividad funcional, Trastornos del neurodesarrollo, Neuroimagen. Resumen: Three leading neurobiological hypotheses about autism spectrum disorder (ASD) propose underconnectivity between brain regions, atypical function of the amygdala, and generally higher variability between individuals with ASD than between neurotypical individuals. Past work has often failed to generalize, because of small sample sizes, unquantified data quality, and analytic flexibility. Link: ./index.php?lvl=notice_display&id=31520 [artículo] Resting-state functional connectivity of the amygdala in autism: a preregistered large-scale study [texto impreso] / Dorit Kliemann, Autor ; Paola Galdi, Autor ; Avery L. Van De Water, Autor . - 2025 . - pp. 1076-1085. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2024 - Vol. 181 - No. 12 (Diciembre) . - pp. 1076-1085 Palabras clave: Trastorno del espectro autista, Neurociencia cognitiva, Conectividad funcional, Trastornos del neurodesarrollo, Neuroimagen. Resumen: Three leading neurobiological hypotheses about autism spectrum disorder (ASD) propose underconnectivity between brain regions, atypical function of the amygdala, and generally higher variability between individuals with ASD than between neurotypical individuals. Past work has often failed to generalize, because of small sample sizes, unquantified data quality, and analytic flexibility. Link: ./index.php?lvl=notice_display&id=31520

Translational insights from cell type variation across amygdala subnuclei in rhesus monkeys and humans / Shawn Kamboj en The American Journal of Psychiatry, Año 2024 - Vol. 181 - No. 12 (Diciembre)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2024 - Vol. 181 - No. 12 (Diciembre) . - pp. 1086-1102 Título : Translational insights from cell type variation across amygdala subnuclei in rhesus monkeys and humans Tipo de documento: texto impreso Autores: Shawn Kamboj, Autor ; Erin L. Carlson, Autor ; Bradley P. Ander, Autor Fecha de publicación: 2025 Artículo en la página: pp. 1086-1102 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastornos de ansiedad, Trastornos depresivos, Genética - Genómica, Neurociencia, Célula única. Resumen: Theories of amygdala function are central to our understanding of psychiatric and neurodevelopmental disorders. However, limited knowledge of the molecular and cellular composition of the amygdala impedes translational research aimed at developing new treatments and interventions. Link: ./index.php?lvl=notice_display&id=31521 [artículo] Translational insights from cell type variation across amygdala subnuclei in rhesus monkeys and humans [texto impreso] / Shawn Kamboj, Autor ; Erin L. Carlson, Autor ; Bradley P. Ander, Autor . - 2025 . - pp. 1086-1102. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2024 - Vol. 181 - No. 12 (Diciembre) . - pp. 1086-1102 Palabras clave: Trastornos de ansiedad, Trastornos depresivos, Genética - Genómica, Neurociencia, Célula única. Resumen: Theories of amygdala function are central to our understanding of psychiatric and neurodevelopmental disorders. However, limited knowledge of the molecular and cellular composition of the amygdala impedes translational research aimed at developing new treatments and interventions. Link: ./index.php?lvl=notice_display&id=31521

Pathways to homelessness: childhood maltreatment and psychiatric symptoms increase risk of homelessness / Cathy Spatz Widom en The American Journal of Psychiatry, Año 2024 - Vol. 181 - No. 12 (Diciembre)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2024 - Vol. 181 - No. 12 (Diciembre) . - pp. 1103–1111 Título : Pathways to homelessness: childhood maltreatment and psychiatric symptoms increase risk of homelessness Tipo de documento: texto impreso Autores: Cathy Spatz Widom, Autor ; Kellie Courtney, Autor ; Hang Heather Do, Autor Fecha de publicación: 2025 Artículo en la página: pp. 1103–1111 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastornos de la personalidad, Trastorno de estrés postraumático (TEPT), Trastornos relacionados con sustancias y adictivos. Resumen: Homelessness is a serious and increasing public health concern. Childhood maltreatment and psychiatric problems have been associated with homelessness as risk factors; however, reliance on cross-sectional studies introduces ambiguity into interpreting previous findings. This study seeks to understand whether psychiatric symptoms in part explain the relationship between childhood maltreatment and homelessness. Link: ./index.php?lvl=notice_display&id=31522 [artículo] Pathways to homelessness: childhood maltreatment and psychiatric symptoms increase risk of homelessness [texto impreso] / Cathy Spatz Widom, Autor ; Kellie Courtney, Autor ; Hang Heather Do, Autor . - 2025 . - pp. 1103–1111. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2024 - Vol. 181 - No. 12 (Diciembre) . - pp. 1103–1111 Palabras clave: Trastornos de la personalidad, Trastorno de estrés postraumático (TEPT), Trastornos relacionados con sustancias y adictivos. Resumen: Homelessness is a serious and increasing public health concern. Childhood maltreatment and psychiatric problems have been associated with homelessness as risk factors; however, reliance on cross-sectional studies introduces ambiguity into interpreting previous findings. This study seeks to understand whether psychiatric symptoms in part explain the relationship between childhood maltreatment and homelessness. Link: ./index.php?lvl=notice_display&id=31522

Discrimination exposure, neural reactivity to stress, and psychological distress / Devon K Grey en The American Journal of Psychiatry, Año 2024 - Vol. 181 - No. 12 (Diciembre)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2024 - Vol. 181 - No. 12 (Diciembre) . - pp. 1112-1126 Título : Discrimination exposure, neural reactivity to stress, and psychological distress Tipo de documento: texto impreso Autores: Devon K Grey, Autor ; Juliann B. Purcell, Autor ; Kristen N Buford, Autor Fecha de publicación: 2025 Artículo en la página: pp. 1112-1126 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Neuroimagen, Cuestiones sociopolíticas, Estigma - discriminación, Estrés. Resumen: Discrimination exposure has a detrimental impact on mental health, increasing the risk of depression, anxiety, and posttraumatic stress. The impact discrimination exposure has on mental health is likely mediated by neural processes associated with emotion expression and regulation. However, the specific neural processes that mediate the relationship between discrimination exposure and mental health remain to be determined. Link: ./index.php?lvl=notice_display&id=31523 [artículo] Discrimination exposure, neural reactivity to stress, and psychological distress [texto impreso] / Devon K Grey, Autor ; Juliann B. Purcell, Autor ; Kristen N Buford, Autor . - 2025 . - pp. 1112-1126. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2024 - Vol. 181 - No. 12 (Diciembre) . - pp. 1112-1126 Palabras clave: Neuroimagen, Cuestiones sociopolíticas, Estigma - discriminación, Estrés. Resumen: Discrimination exposure has a detrimental impact on mental health, increasing the risk of depression, anxiety, and posttraumatic stress. The impact discrimination exposure has on mental health is likely mediated by neural processes associated with emotion expression and regulation. However, the specific neural processes that mediate the relationship between discrimination exposure and mental health remain to be determined. Link: ./index.php?lvl=notice_display&id=31523