Biblioteca Humberto Rosselli Quijano
Información del autor
Autor John L. Waddington |
Documentos disponibles escritos por este autor (4)
Refinar búsqueda20 year prospective, sequential follow up study of heterogeneity in associations of duration of untreated psychosis with symptoms, functioning, and quality of life following first episode psychosis / Donal O’Keeffe en The American Journal of Psychiatry, Año 2022 - Vol. 179 - No. 4 (Abril)
Título : 20 year prospective, sequential follow up study of heterogeneity in associations of duration of untreated psychosis with symptoms, functioning, and quality of life following first episode psychosis Tipo de documento: texto impreso Autores: Donal O’Keeffe, Autor ; Anthony Kinsella, Autor ; John L. Waddington, Autor Fecha de publicación: 2022 Artículo en la página: pp. 288-297 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Psicosis de primer episodio, Enfermedad psicótica, Duración de la psicosis no tratada, Sintomatología, Funcionamiento, Calidad de vida, Heterogeneidad. Resumen: Determining the extent to which relationships between duration of untreated psychosis (DUP) and outcome endure longitudinally across the lifetime course of psychotic illness requires prospective, systematic studies of epidemiologically representative incidence cohorts across decades. Transience, persistence, or heterogeneity in associations between DUP and distinct outcome domains are yet to be investigated over such time frames. Link: ./index.php?lvl=notice_display&id=28453
in The American Journal of Psychiatry > Año 2022 - Vol. 179 - No. 4 (Abril) . - pp. 288-297[artículo] 20 year prospective, sequential follow up study of heterogeneity in associations of duration of untreated psychosis with symptoms, functioning, and quality of life following first episode psychosis [texto impreso] / Donal O’Keeffe, Autor ; Anthony Kinsella, Autor ; John L. Waddington, Autor . - 2022 . - pp. 288-297.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in The American Journal of Psychiatry > Año 2022 - Vol. 179 - No. 4 (Abril) . - pp. 288-297
Palabras clave: Psicosis de primer episodio, Enfermedad psicótica, Duración de la psicosis no tratada, Sintomatología, Funcionamiento, Calidad de vida, Heterogeneidad. Resumen: Determining the extent to which relationships between duration of untreated psychosis (DUP) and outcome endure longitudinally across the lifetime course of psychotic illness requires prospective, systematic studies of epidemiologically representative incidence cohorts across decades. Transience, persistence, or heterogeneity in associations between DUP and distinct outcome domains are yet to be investigated over such time frames. Link: ./index.php?lvl=notice_display&id=28453
Título : Functional genomics and schizophrenia : endophenotypes and mutant models Tipo de documento: texto impreso Autores: John L. Waddington, Autor ; Aiden P. Corvin, Autor ; Gary Donohoe, Autor Fecha de publicación: 2020 Artículo en la página: pp. 365-399 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Predisposición genética a enfermedades, Genómica, Modelos genéticos, Mutación, Esquizofrenia. Resumen: This article summarizes the rationale, methods, and results of gene discovery programs in schizophrenia research and describes functional methods of investigating potential candidate genes. Link: ./index.php?lvl=notice_display&id=24561
in Psychiatric Clinics of North America > Año 2007 - Vol.30 No. 3 (Septiembre) . - pp. 365-399[artículo] Functional genomics and schizophrenia : endophenotypes and mutant models [texto impreso] / John L. Waddington, Autor ; Aiden P. Corvin, Autor ; Gary Donohoe, Autor . - 2020 . - pp. 365-399.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Psychiatric Clinics of North America > Año 2007 - Vol.30 No. 3 (Septiembre) . - pp. 365-399
Palabras clave: Predisposición genética a enfermedades, Genómica, Modelos genéticos, Mutación, Esquizofrenia. Resumen: This article summarizes the rationale, methods, and results of gene discovery programs in schizophrenia research and describes functional methods of investigating potential candidate genes. Link: ./index.php?lvl=notice_display&id=24561
Título : Genetically modified mice related to schizophrenia and other psychoses : Seeking phenotypic insights into the pathobiology and treatment of negative symptoms Tipo de documento: texto impreso Autores: Colm M. P. O'Tuathaigh, Autor ; Lieve Desbonnet, Autor ; John L. Waddington, Autor Fecha de publicación: 2021 Artículo en la página: pp. 800-821 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Síntomas negativos, Esquizofrenia, Modelos de ratones mutantes, Comportamiento social, Mutantes de genes candidatos, Fenotipado conductual, Dopamina, Glutamato Resumen: Modelling negative symptoms in any animal model, particularly in mice mutant for genes related to schizophrenia, is complicated by the absence of the following key elements that might assist in developing validation criteria: clinical clarity surrounding this symptom constellation;... Link: ./index.php?lvl=notice_display&id=26994
in European Neuropsychopharmacology > Año 2014 - Vol. 24 - No.5 (Mayo) . - pp. 800-821[artículo] Genetically modified mice related to schizophrenia and other psychoses : Seeking phenotypic insights into the pathobiology and treatment of negative symptoms [texto impreso] / Colm M. P. O'Tuathaigh, Autor ; Lieve Desbonnet, Autor ; John L. Waddington, Autor . - 2021 . - pp. 800-821.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in European Neuropsychopharmacology > Año 2014 - Vol. 24 - No.5 (Mayo) . - pp. 800-821
Palabras clave: Síntomas negativos, Esquizofrenia, Modelos de ratones mutantes, Comportamiento social, Mutantes de genes candidatos, Fenotipado conductual, Dopamina, Glutamato Resumen: Modelling negative symptoms in any animal model, particularly in mice mutant for genes related to schizophrenia, is complicated by the absence of the following key elements that might assist in developing validation criteria: clinical clarity surrounding this symptom constellation;... Link: ./index.php?lvl=notice_display&id=26994
Título : Neurodevelopmental and neuroprogressive processes in schizophrenia : antithetical or complementary, over a lifetime trajectory of disease? Tipo de documento: texto impreso Autores: John L. Waddington, Autor ; Abbie Lane, Autor ; Paul J. Scully, Autor Fecha de publicación: 2020 Artículo en la página: pp. 123-149 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Cerebro, Anomalías craneofaciales, Enfermedad progresiva, Degeneración nerviosa, Esquizofrenia. Resumen: The neurodevelopmental model of schizophrenia maintains ascendancy among current etiopathologic perspectives on schizophrenia. However, inconsistencies across studies and the absence thus far of pathognomic brain changes suggest the need for complex conceptualization of neurodevelopmental arrest, including some reconciliation with the competing neurodegenerative model of schizophrenia. Link: ./index.php?lvl=notice_display&id=25072
in Psychiatric Clinics of North America > Año 1998- Vol. 21 No. 1 (Marzo) . - pp. 123-149[artículo] Neurodevelopmental and neuroprogressive processes in schizophrenia : antithetical or complementary, over a lifetime trajectory of disease? [texto impreso] / John L. Waddington, Autor ; Abbie Lane, Autor ; Paul J. Scully, Autor . - 2020 . - pp. 123-149.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Psychiatric Clinics of North America > Año 1998- Vol. 21 No. 1 (Marzo) . - pp. 123-149
Palabras clave: Cerebro, Anomalías craneofaciales, Enfermedad progresiva, Degeneración nerviosa, Esquizofrenia. Resumen: The neurodevelopmental model of schizophrenia maintains ascendancy among current etiopathologic perspectives on schizophrenia. However, inconsistencies across studies and the absence thus far of pathognomic brain changes suggest the need for complex conceptualization of neurodevelopmental arrest, including some reconciliation with the competing neurodegenerative model of schizophrenia. Link: ./index.php?lvl=notice_display&id=25072
