Regulation of melanocortin-4-receptor (MC4R) expression by SNP rs17066842 is dependent on glucose concentration / Li Qin en European Neuropsychopharmacology, Año 2020 - Vol.37 (Agosto)

Público ISBD [artículo]  inEuropean Neuropsychopharmacology > Año 2020 - Vol.37 (Agosto) . - pp. 39-48 Título : Regulation of melanocortin-4-receptor (MC4R) expression by SNP rs17066842 is dependent on glucose concentration Tipo de documento: texto impreso Autores: Li Qin, Autor ; Arun Kumar Tiwari, Autor ; Clement C. Zai, Autor Fecha de publicación: 2021 Artículo en la página: pp. 39-48 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: MC4R rs17066842, EGR-1, Glucosa, Obesidad, Diabetes tipo 2, Organoides cerebrales Resumen: Melanocortin-4-receptor (MC4R) gene codes for a G-protein-coupled receptor that is highly expressed in the hypothalamus and involved in the regulation of appetite. Single-nucleotide polymorphisms (SNPs) in the MC4R gene region have been associated with obesity, type 2-diabetes (T2D) and with antipsychotic-induced weight gain. Link: ./index.php?lvl=notice_display&id=26319 [artículo] Regulation of melanocortin-4-receptor (MC4R) expression by SNP rs17066842 is dependent on glucose concentration [texto impreso] / Li Qin, Autor ; Arun Kumar Tiwari, Autor ; Clement C. Zai, Autor . - 2021 . - pp. 39-48. Idioma : Inglés (eng) Idioma original : Inglés (eng) in European Neuropsychopharmacology > Año 2020 - Vol.37 (Agosto) . - pp. 39-48 Palabras clave: MC4R rs17066842, EGR-1, Glucosa, Obesidad, Diabetes tipo 2, Organoides cerebrales Resumen: Melanocortin-4-receptor (MC4R) gene codes for a G-protein-coupled receptor that is highly expressed in the hypothalamus and involved in the regulation of appetite. Single-nucleotide polymorphisms (SNPs) in the MC4R gene region have been associated with obesity, type 2-diabetes (T2D) and with antipsychotic-induced weight gain. Link: ./index.php?lvl=notice_display&id=26319

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