Psychiatric polygenic risk scores across youth with bipolar disorder, youth at high risk for bipolar disorder, and controls / Xinyue Jiang en Journal of the American Academy of Child & Adolescent Psychiatry, Año 2024 - Vol. 63 - No. 11 (Noviembre)

Público ISBD [artículo]  inJournal of the American Academy of Child & Adolescent Psychiatry > Año 2024 - Vol. 63 - No. 11 (Noviembre) . - pp. 1149-1157 Título : Psychiatric polygenic risk scores across youth with bipolar disorder, youth at high risk for bipolar disorder, and controls Tipo de documento: texto impreso Autores: Xinyue Jiang, Autor ; Clement C. Zai, Autor ; Mikaela K. Dimick, Autor Fecha de publicación: 2024 Artículo en la página: pp. 1149-1157 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastorno bipolar, Alto riesgo, Puntuación de riesgo poligénico, Juventud Resumen: There is a pronounced gap in knowledge regarding polygenic underpinnings of youth bipolar disorder (BD). This study aimed to compare polygenic risk scores (PRSs) in youth with BD, youth at high clinical and/or familial risk for BD (HR), and controls. Link: ./index.php?lvl=notice_display&id=31488 [artículo] Psychiatric polygenic risk scores across youth with bipolar disorder, youth at high risk for bipolar disorder, and controls [texto impreso] / Xinyue Jiang, Autor ; Clement C. Zai, Autor ; Mikaela K. Dimick, Autor . - 2024 . - pp. 1149-1157. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of the American Academy of Child & Adolescent Psychiatry > Año 2024 - Vol. 63 - No. 11 (Noviembre) . - pp. 1149-1157 Palabras clave: Trastorno bipolar, Alto riesgo, Puntuación de riesgo poligénico, Juventud Resumen: There is a pronounced gap in knowledge regarding polygenic underpinnings of youth bipolar disorder (BD). This study aimed to compare polygenic risk scores (PRSs) in youth with BD, youth at high clinical and/or familial risk for BD (HR), and controls. Link: ./index.php?lvl=notice_display&id=31488

Finite mixture regression model analysis on antipsychotics induced weight gain / Behdin Nowrouzi Kia en European Neuropsychopharmacology, Año 2013 - Vol. 23 - No.3 (Marzo)

Público ISBD [artículo]  inEuropean Neuropsychopharmacology > Año 2013 - Vol. 23 - No.3 (Marzo) . - pp. 224-228 Título : Finite mixture regression model analysis on antipsychotics induced weight gain : Investigation of the role of the serotonergic genes Tipo de documento: texto impreso Autores: Behdin Nowrouzi Kia, Autor ; Renan Pedra de Souza, Autor ; Clement C. Zai, Autor Fecha de publicación: 2021 Artículo en la página: pp. 224-228 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Esquizofrenia, Antipsicóticos, Aumento de peso, Genética, Serotonina, FMM Resumen: Antipsychotics-induced weight gain is a complex phenomenon with a relevant underlying genetic basis. Polymorphisms of serotonin receptors and related proteins were genotyped in 139 schizophrenia patients and incorporated as covariates in a mixture regression model of weight gain in combination with clinical covariates. Link: ./index.php?lvl=notice_display&id=27074 [artículo] Finite mixture regression model analysis on antipsychotics induced weight gain : Investigation of the role of the serotonergic genes [texto impreso] / Behdin Nowrouzi Kia, Autor ; Renan Pedra de Souza, Autor ; Clement C. Zai, Autor . - 2021 . - pp. 224-228. Idioma : Inglés (eng) Idioma original : Inglés (eng) in European Neuropsychopharmacology > Año 2013 - Vol. 23 - No.3 (Marzo) . - pp. 224-228 Palabras clave: Esquizofrenia, Antipsicóticos, Aumento de peso, Genética, Serotonina, FMM Resumen: Antipsychotics-induced weight gain is a complex phenomenon with a relevant underlying genetic basis. Polymorphisms of serotonin receptors and related proteins were genotyped in 139 schizophrenia patients and incorporated as covariates in a mixture regression model of weight gain in combination with clinical covariates. Link: ./index.php?lvl=notice_display&id=27074

Regulation of melanocortin-4-receptor (MC4R) expression by SNP rs17066842 is dependent on glucose concentration / Li Qin en European Neuropsychopharmacology, Año 2020 - Vol.37 (Agosto)

Público ISBD [artículo]  inEuropean Neuropsychopharmacology > Año 2020 - Vol.37 (Agosto) . - pp. 39-48 Título : Regulation of melanocortin-4-receptor (MC4R) expression by SNP rs17066842 is dependent on glucose concentration Tipo de documento: texto impreso Autores: Li Qin, Autor ; Arun Kumar Tiwari, Autor ; Clement C. Zai, Autor Fecha de publicación: 2021 Artículo en la página: pp. 39-48 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: MC4R rs17066842, EGR-1, Glucosa, Obesidad, Diabetes tipo 2, Organoides cerebrales Resumen: Melanocortin-4-receptor (MC4R) gene codes for a G-protein-coupled receptor that is highly expressed in the hypothalamus and involved in the regulation of appetite. Single-nucleotide polymorphisms (SNPs) in the MC4R gene region have been associated with obesity, type 2-diabetes (T2D) and with antipsychotic-induced weight gain. Link: ./index.php?lvl=notice_display&id=26319 [artículo] Regulation of melanocortin-4-receptor (MC4R) expression by SNP rs17066842 is dependent on glucose concentration [texto impreso] / Li Qin, Autor ; Arun Kumar Tiwari, Autor ; Clement C. Zai, Autor . - 2021 . - pp. 39-48. Idioma : Inglés (eng) Idioma original : Inglés (eng) in European Neuropsychopharmacology > Año 2020 - Vol.37 (Agosto) . - pp. 39-48 Palabras clave: MC4R rs17066842, EGR-1, Glucosa, Obesidad, Diabetes tipo 2, Organoides cerebrales Resumen: Melanocortin-4-receptor (MC4R) gene codes for a G-protein-coupled receptor that is highly expressed in the hypothalamus and involved in the regulation of appetite. Single-nucleotide polymorphisms (SNPs) in the MC4R gene region have been associated with obesity, type 2-diabetes (T2D) and with antipsychotic-induced weight gain. Link: ./index.php?lvl=notice_display&id=26319

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