Functional mechanism of ASP5736, a selective serotonin 5-HT5A receptor antagonist with potential utility for the treatment of cognitive dysfunction in schizophrenia / Mayako Yamazaki en European Neuropsychopharmacology, Año 2018 - Vol. 28 - No. 5 (Mayo)

Público ISBD [artículo]  inEuropean Neuropsychopharmacology > Año 2018 - Vol. 28 - No. 5 (Mayo) . - pp. 620-629 Título : Functional mechanism of ASP5736, a selective serotonin 5-HT5A receptor antagonist with potential utility for the treatment of cognitive dysfunction in schizophrenia Tipo de documento: texto impreso Autores: Mayako Yamazaki, Autor ; Noriyuki Yamamoto, Autor ; Junko Yarimizu, Autor Fecha de publicación: 2021 Artículo en la página: pp. 620-629 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antagonista del receptor 5-HT5A, Esquizofrenia, Cognición, Inmunohistoquímica, Microdiálisis, Estudios electrofisiológicos Resumen: The 5-HT5A receptor is arguably the least understood 5-HT receptor. Despite widespread expression in human and rodent brains it lacks specific ligands. Our previous results suggest that 5-HT5A receptor antagonists may be effective against cognitive impairment in schizophrenia. Link: ./index.php?lvl=notice_display&id=26418 [artículo] Functional mechanism of ASP5736, a selective serotonin 5-HT5A receptor antagonist with potential utility for the treatment of cognitive dysfunction in schizophrenia [texto impreso] / Mayako Yamazaki, Autor ; Noriyuki Yamamoto, Autor ; Junko Yarimizu, Autor . - 2021 . - pp. 620-629. Idioma : Inglés (eng) Idioma original : Inglés (eng) in European Neuropsychopharmacology > Año 2018 - Vol. 28 - No. 5 (Mayo) . - pp. 620-629 Palabras clave: Antagonista del receptor 5-HT5A, Esquizofrenia, Cognición, Inmunohistoquímica, Microdiálisis, Estudios electrofisiológicos Resumen: The 5-HT5A receptor is arguably the least understood 5-HT receptor. Despite widespread expression in human and rodent brains it lacks specific ligands. Our previous results suggest that 5-HT5A receptor antagonists may be effective against cognitive impairment in schizophrenia. Link: ./index.php?lvl=notice_display&id=26418

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