Pleiotrophin overexpression regulates amphetamine-induced reward and striatal dopaminergic denervation without changing the expression of dopamine D1 and D2 receptors / Marta Vicente Rodríguez en European Neuropsychopharmacology, Año 2016 - Vol. 26 - No. 11 (Noviembre)

Público ISBD [artículo]  inEuropean Neuropsychopharmacology > Año 2016 - Vol. 26 - No. 11 (Noviembre) . - pp. 1794-1805 Título : Pleiotrophin overexpression regulates amphetamine-induced reward and striatal dopaminergic denervation without changing the expression of dopamine D1 and D2 receptors : Implications for neuroinflammation Tipo de documento: texto impreso Autores: Marta Vicente Rodríguez, Autor ; Loreto Rojo Gonzalez, Autor ; Esther Gramage, Autor Fecha de publicación: 2021 Artículo en la página: pp. 1794-1805 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Pleiotrofina, Midkine, Astrogliosis, Inflamación, Metanfetamina, Recompensa Resumen: It was previously shown that mice with genetic deletion of the neurotrophic factor pleiotrophin (PTN-/-) show enhanced amphetamine neurotoxicity and impair extinction of amphetamine conditioned place preference (CPP), suggesting a modulatory role of PTN in amphetamine neurotoxicity and reward. Link: ./index.php?lvl=notice_display&id=26473 [artículo] Pleiotrophin overexpression regulates amphetamine-induced reward and striatal dopaminergic denervation without changing the expression of dopamine D1 and D2 receptors : Implications for neuroinflammation [texto impreso] / Marta Vicente Rodríguez, Autor ; Loreto Rojo Gonzalez, Autor ; Esther Gramage, Autor . - 2021 . - pp. 1794-1805. Idioma : Inglés (eng) Idioma original : Inglés (eng) in European Neuropsychopharmacology > Año 2016 - Vol. 26 - No. 11 (Noviembre) . - pp. 1794-1805 Palabras clave: Pleiotrofina, Midkine, Astrogliosis, Inflamación, Metanfetamina, Recompensa Resumen: It was previously shown that mice with genetic deletion of the neurotrophic factor pleiotrophin (PTN-/-) show enhanced amphetamine neurotoxicity and impair extinction of amphetamine conditioned place preference (CPP), suggesting a modulatory role of PTN in amphetamine neurotoxicity and reward. Link: ./index.php?lvl=notice_display&id=26473

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