Biblioteca Humberto Rosselli Quijano
Información del autor
Autor Christine C. Gispen De Wied |
Documentos disponibles escritos por este autor (3)
Refinar búsquedaCNS biomarkers: Potential from a regulatory perspective / Maria B. Isaac en European Neuropsychopharmacology, Año 2015 - Vol. 25 - No.7 (Julio)
Título : CNS biomarkers: Potential from a regulatory perspective : Case study – Focus in low hippocampus volume as a biomarker measured by MRI Tipo de documento: texto impreso Autores: Maria B. Isaac, Autor ; Christine C. Gispen De Wied, Autor Fecha de publicación: 2021 Artículo en la página: pp. 1003-1009 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Biomarcadores, Asesoramiento de cualificación, Opinión de calificación, EMA, FDA Resumen: Our objectives are to describe the procedure for qualification advice and opinion from EU regulators on the use of novel methodologies in drug development, the key stakeholders involved and the evidence requirements for qualification opinion. Link: ./index.php?lvl=notice_display&id=26761
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.7 (Julio) . - pp. 1003-1009[artículo] CNS biomarkers: Potential from a regulatory perspective : Case study – Focus in low hippocampus volume as a biomarker measured by MRI [texto impreso] / Maria B. Isaac, Autor ; Christine C. Gispen De Wied, Autor . - 2021 . - pp. 1003-1009.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.7 (Julio) . - pp. 1003-1009
Palabras clave: Biomarcadores, Asesoramiento de cualificación, Opinión de calificación, EMA, FDA Resumen: Our objectives are to describe the procedure for qualification advice and opinion from EU regulators on the use of novel methodologies in drug development, the key stakeholders involved and the evidence requirements for qualification opinion. Link: ./index.php?lvl=notice_display&id=26761
Título : Effects of typical and atypical antipsychotics on the prepulse inhibition of the startle reflex in patients with schizophrenia Tipo de documento: texto impreso Autores: Bob Oranje, Autor ; Clarine J. van Oel, Autor ; Christine C. Gispen De Wied, Autor Fecha de publicación: 2023 Artículo en la página: pp. 359-365 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Estimulación acústica, Agentes antipsicóticos, Reflejo, sobresalto, Esquizofrenia. Resumen: Patients with schizophrenia show a loss of sensory (motor) gating, which is reflected in a reduced prepulse inhibition (PPI) of the startle reflex. Furthermore, patients with schizophrenia habituate less than healthy subjects. From previous studies, it is clear that typical antipsychotics have little or no effect on either sensorimotor gating or habituation, while only limited data is available on the effects of atypical antipsychotics on these processes. Link: ./index.php?lvl=notice_display&id=31051
in Journal of Clinical Psychopharmacology > Año 2002 - Vol. 22 - No. 4 (Agosto) . - pp. 359-365[artículo] Effects of typical and atypical antipsychotics on the prepulse inhibition of the startle reflex in patients with schizophrenia [texto impreso] / Bob Oranje, Autor ; Clarine J. van Oel, Autor ; Christine C. Gispen De Wied, Autor . - 2023 . - pp. 359-365.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2002 - Vol. 22 - No. 4 (Agosto) . - pp. 359-365
Palabras clave: Estimulación acústica, Agentes antipsicóticos, Reflejo, sobresalto, Esquizofrenia. Resumen: Patients with schizophrenia show a loss of sensory (motor) gating, which is reflected in a reduced prepulse inhibition (PPI) of the startle reflex. Furthermore, patients with schizophrenia habituate less than healthy subjects. From previous studies, it is clear that typical antipsychotics have little or no effect on either sensorimotor gating or habituation, while only limited data is available on the effects of atypical antipsychotics on these processes. Link: ./index.php?lvl=notice_display&id=31051
Título : The effect of olanzapine treatment on m-chlorophenylpiperazine-induced hormone release in schizophrenia Tipo de documento: texto impreso Autores: Floortje E. Scheepers, Autor ; Christine C. Gispen De Wied, Autor ; René S. Kahn, Autor Fecha de publicación: 2023 Artículo en la página: pp. 575-582 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Hormona adrenocorticotrópica, Benzodiazepinas, Hormonas - metabolismo, Piperazinas, Prolactina, Receptor de serotonina 5-HT2C, Esquizofrenia. Resumen: In addition to dopamine, serotonin (5-hydroxytryptamine, 5-HT) has been reported to play an important role in schizophrenia. Besides blocking dopamine, atypical antipsychotics also block 5-HT receptors. The clinical efficacy of the atypical antipsychotic clozapine is associated with the 5-HT antagonistic action of the drug and a high serotonergic tone before treatment. Link: ./index.php?lvl=notice_display&id=31103
in Journal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 6 (Diciembre) . - pp. 575-582[artículo] The effect of olanzapine treatment on m-chlorophenylpiperazine-induced hormone release in schizophrenia [texto impreso] / Floortje E. Scheepers, Autor ; Christine C. Gispen De Wied, Autor ; René S. Kahn, Autor . - 2023 . - pp. 575-582.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 6 (Diciembre) . - pp. 575-582
Palabras clave: Hormona adrenocorticotrópica, Benzodiazepinas, Hormonas - metabolismo, Piperazinas, Prolactina, Receptor de serotonina 5-HT2C, Esquizofrenia. Resumen: In addition to dopamine, serotonin (5-hydroxytryptamine, 5-HT) has been reported to play an important role in schizophrenia. Besides blocking dopamine, atypical antipsychotics also block 5-HT receptors. The clinical efficacy of the atypical antipsychotic clozapine is associated with the 5-HT antagonistic action of the drug and a high serotonergic tone before treatment. Link: ./index.php?lvl=notice_display&id=31103
