Electroconvulsive shocks decrease α2-adrenoceptor binding in the Flinders rat model of depression / Thea Pinholt Lillethorup en European Neuropsychopharmacology, Año 2015 - Vol. 25 - No.3 (Marzo)

Público ISBD [artículo]  inEuropean Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 404-412 Título : Electroconvulsive shocks decrease α2-adrenoceptor binding in the Flinders rat model of depression Tipo de documento: texto impreso Autores: Thea Pinholt Lillethorup, Autor ; Peter Iversen, Autor ; Jesper Fontain, Autor Fecha de publicación: 2021 Artículo en la página: pp. 404-412 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Ratas, Flinders, Adrenoceptores α  2, Terapia electroconvulsiva, Autorradiografia Resumen: Despite years of drug development, electroconvulsive therapy (ECT) remains the most effective treatment for severe depression. The exact therapeutic mechanism of action of ECT is still unresolved and therefore we tested the hypothesis that the beneficial effect of ECT could in part be the result of increased noradrenergic neurotransmission leading to a decrease in α2-adrenoceptor binding. Link: ./index.php?lvl=notice_display&id=26820 [artículo] Electroconvulsive shocks decrease α2-adrenoceptor binding in the Flinders rat model of depression [texto impreso] / Thea Pinholt Lillethorup, Autor ; Peter Iversen, Autor ; Jesper Fontain, Autor . - 2021 . - pp. 404-412. Idioma : Inglés (eng) Idioma original : Inglés (eng) in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 404-412 Palabras clave: Ratas, Flinders, Adrenoceptores α  2, Terapia electroconvulsiva, Autorradiografia Resumen: Despite years of drug development, electroconvulsive therapy (ECT) remains the most effective treatment for severe depression. The exact therapeutic mechanism of action of ECT is still unresolved and therefore we tested the hypothesis that the beneficial effect of ECT could in part be the result of increased noradrenergic neurotransmission leading to a decrease in α2-adrenoceptor binding. Link: ./index.php?lvl=notice_display&id=26820

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