Effects of gabapentin on dorsal anterior cingulate cortex gaba and glutamate levels and their associations with abstinence in alcohol use disorder / James J. Prisciandaro en The American Journal of Psychiatry, Año 2021 - Vol. 178 - No.9 (Septiembre)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2021 - Vol. 178 - No.9 (Septiembre) . - pp. 829-837 Título : Effects of gabapentin on dorsal anterior cingulate cortex gaba and glutamate levels and their associations with abstinence in alcohol use disorder : a randomized clinical trial Tipo de documento: texto impreso Autores: James J. Prisciandaro, Autor ; Michaela Hoffman, Autor ; Truman R. Brown, Autor Fecha de publicación: 2021 Artículo en la página: pp. 829-837 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Neuroimagen, Trastornos adictivos y relacionados con sustancias, Alcohol, Anticonvulsivos Resumen: Although gabapentin has demonstrated efficacy in mitigating alcohol withdrawal symptoms and preventing relapse drinking in individuals with alcohol use disorder (AUD), the neurobiological mechanisms of action underlying these therapeutic effects remain unknown. The present study evaluated changes in GABA and glutamate levels in the dorsal anterior cingulate cortex (dACC) as candidate mechanisms of action. Link: ./index.php?lvl=notice_display&id=27334 [artículo] Effects of gabapentin on dorsal anterior cingulate cortex gaba and glutamate levels and their associations with abstinence in alcohol use disorder : a randomized clinical trial [texto impreso] / James J. Prisciandaro, Autor ; Michaela Hoffman, Autor ; Truman R. Brown, Autor . - 2021 . - pp. 829-837. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2021 - Vol. 178 - No.9 (Septiembre) . - pp. 829-837 Palabras clave: Neuroimagen, Trastornos adictivos y relacionados con sustancias, Alcohol, Anticonvulsivos Resumen: Although gabapentin has demonstrated efficacy in mitigating alcohol withdrawal symptoms and preventing relapse drinking in individuals with alcohol use disorder (AUD), the neurobiological mechanisms of action underlying these therapeutic effects remain unknown. The present study evaluated changes in GABA and glutamate levels in the dorsal anterior cingulate cortex (dACC) as candidate mechanisms of action. Link: ./index.php?lvl=notice_display&id=27334

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