Pregnenolone and dehydroepiandrosterone as an adjunctive treatment in schizophrenia and schizoaffective disorder / Michael S. Ritsner en The Journal of Clinical Psychiatry, Año 2010 - Vol. 71 - No. 10 (Octubre)

Público ISBD [artículo]  inThe Journal of Clinical Psychiatry > Año 2010 - Vol. 71 - No. 10 (Octubre) . - pp. 1351-1362 Título : Pregnenolone and dehydroepiandrosterone as an adjunctive treatment in schizophrenia and schizoaffective disorder : an 8 week, double blind, randomized, controlled, 2 center, parallel group trial Tipo de documento: texto impreso Autores: Michael S. Ritsner, Autor ; Anatoly Gibel, Autor ; Tatyana Shleifer, Autor Fecha de publicación: 2022 Artículo en la página: pp. 1351-1362 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Dehidroepiandrosterona, Farmacoterapia, combinación, Discinesia inducida por fármacos, Memoria a corto plazo, Neurotransmisores, Pregnenolona, Trastornos psicóticos, Esquizofrenia, Índice de gravedad de la enfermedad. Resumen: Pregnenolone (PREG) and dehydroepiandrosterone (DHEA) are reported to have a modulatory effect on neuronal excitability, synaptic plasticity, and response to stress; they are associated with mood regulation and cognitive performance. We investigated the influence of PREG and DHEA on psychotic symptoms and cognitive functioning as an add-on to ongoing antipsychotic treatment of patients with chronic schizophrenia or schizoaffective disorder. Link: ./index.php?lvl=notice_display&id=28247 [artículo] Pregnenolone and dehydroepiandrosterone as an adjunctive treatment in schizophrenia and schizoaffective disorder : an 8 week, double blind, randomized, controlled, 2 center, parallel group trial [texto impreso] / Michael S. Ritsner, Autor ; Anatoly Gibel, Autor ; Tatyana Shleifer, Autor . - 2022 . - pp. 1351-1362. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The Journal of Clinical Psychiatry > Año 2010 - Vol. 71 - No. 10 (Octubre) . - pp. 1351-1362 Palabras clave: Antipsicóticos, Dehidroepiandrosterona, Farmacoterapia, combinación, Discinesia inducida por fármacos, Memoria a corto plazo, Neurotransmisores, Pregnenolona, Trastornos psicóticos, Esquizofrenia, Índice de gravedad de la enfermedad. Resumen: Pregnenolone (PREG) and dehydroepiandrosterone (DHEA) are reported to have a modulatory effect on neuronal excitability, synaptic plasticity, and response to stress; they are associated with mood regulation and cognitive performance. We investigated the influence of PREG and DHEA on psychotic symptoms and cognitive functioning as an add-on to ongoing antipsychotic treatment of patients with chronic schizophrenia or schizoaffective disorder. Link: ./index.php?lvl=notice_display&id=28247

Quality of life outcomes of risperidone, olanzapine, and typical antipsychotics among schizophrenia patients treated in routine clinical practice / Michael S. Ritsner en Journal of Clinical Psychopharmacology, Año 2004 - Vol. 24 - No. 6 (Diciembre)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 6 (Diciembre) . - PP. 582-591 Título : Quality of life outcomes of risperidone, olanzapine, and typical antipsychotics among schizophrenia patients treated in routine clinical practice : A naturalistic comparative study Tipo de documento: texto impreso Autores: Michael S. Ritsner, Autor ; Anatoly Gibel, Autor ; Galina Perelroyzen, Autor Fecha de publicación: 2023 Artículo en la página: PP. 582-591 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Atención Ambulatoria, Antipsicóticos, Benzodiacepinas, Calidad de Vida, Risperidona, Esquizofrenia, Psicología esquizofrénica. Resumen: Findings in previous studies investigating the beneficial effect of risperidone and olanzapine versus typical antipsychotics on quality of life (QOL) are controversial since they did not adjust for various factors contributing to QOL. To test this assumption in a naturalistic cross-sectional design, we evaluated general and domain-specific QOL scores for baseline data of schizophrenia outpatients stabilized on atypical (N = 78, risperidone or olanzapine) and typical (N = 55) agents. Link: ./index.php?lvl=notice_display&id=30929 [artículo] Quality of life outcomes of risperidone, olanzapine, and typical antipsychotics among schizophrenia patients treated in routine clinical practice : A naturalistic comparative study [texto impreso] / Michael S. Ritsner, Autor ; Anatoly Gibel, Autor ; Galina Perelroyzen, Autor . - 2023 . - PP. 582-591. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 6 (Diciembre) . - PP. 582-591 Palabras clave: Atención Ambulatoria, Antipsicóticos, Benzodiacepinas, Calidad de Vida, Risperidona, Esquizofrenia, Psicología esquizofrénica. Resumen: Findings in previous studies investigating the beneficial effect of risperidone and olanzapine versus typical antipsychotics on quality of life (QOL) are controversial since they did not adjust for various factors contributing to QOL. To test this assumption in a naturalistic cross-sectional design, we evaluated general and domain-specific QOL scores for baseline data of schizophrenia outpatients stabilized on atypical (N = 78, risperidone or olanzapine) and typical (N = 55) agents. Link: ./index.php?lvl=notice_display&id=30929

The retinoid X receptor agonist bexarotene relieves positive symptoms of schizophrenia / Vladimir Lerner en The Journal of Clinical Psychiatry, Año 2013 - Vol.74 - No.12 (Diciembre)

Público ISBD [artículo]  inThe Journal of Clinical Psychiatry > Año 2013 - Vol.74 - No.12 (Diciembre) . - pp. 1224-1232 Título : The retinoid X receptor agonist bexarotene relieves positive symptoms of schizophrenia : a 6-week, randomized, double-blind, placebo-controlled multicenter trial Tipo de documento: texto impreso Autores: Vladimir Lerner, Autor ; Chanoch Miodownik, Autor ; Anatoly Gibel, Autor Fecha de publicación: 2022 Artículo en la página: pp. 1224-1232 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Terapia farmacológica, Trastornos psicóticos, Calidad de vida, Esquizofrenia, Psicología esquizofrénica. Resumen: The limitations of antipsychotic therapy in schizophrenia and schizoaffective disorder led to the investigation of the putative utility of pharmacologic augmentation strategies. The antitumor agent bexarotene via nuclear retinoid X receptor (RXR) activation might modulate numerous metabolic pathways involved in the pathogenesis of schizophrenia and schizoaffective disorder. Link: ./index.php?lvl=notice_display&id=27912 [artículo] The retinoid X receptor agonist bexarotene relieves positive symptoms of schizophrenia : a 6-week, randomized, double-blind, placebo-controlled multicenter trial [texto impreso] / Vladimir Lerner, Autor ; Chanoch Miodownik, Autor ; Anatoly Gibel, Autor . - 2022 . - pp. 1224-1232. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The Journal of Clinical Psychiatry > Año 2013 - Vol.74 - No.12 (Diciembre) . - pp. 1224-1232 Palabras clave: Antipsicóticos, Terapia farmacológica, Trastornos psicóticos, Calidad de vida, Esquizofrenia, Psicología esquizofrénica. Resumen: The limitations of antipsychotic therapy in schizophrenia and schizoaffective disorder led to the investigation of the putative utility of pharmacologic augmentation strategies. The antitumor agent bexarotene via nuclear retinoid X receptor (RXR) activation might modulate numerous metabolic pathways involved in the pathogenesis of schizophrenia and schizoaffective disorder. Link: ./index.php?lvl=notice_display&id=27912

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