Candidate gene analysis identifies a polymorphism in HLA-DQB1 associated with clozapine induced agranulocytosis / Maria C. Athanasiou en The Journal of Clinical Psychiatry, Año 2011 - Vol.72 - No. 4 (Abril)

Público ISBD [artículo]  inThe Journal of Clinical Psychiatry > Año 2011 - Vol.72 - No. 4 (Abril) . - pp. 458-463 Título : Candidate gene analysis identifies a polymorphism in HLA-DQB1 associated with clozapine induced agranulocytosis Tipo de documento: texto impreso Autores: Maria C. Athanasiou, Autor ; Michael Dettling, Autor ; Ingolf Cascorbi, Autor Fecha de publicación: 2022 Artículo en la página: pp. 458-463 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Agranulocitosis, Antipsicóticos, Clozapina, Predisposición genética a la enfermedad, Antígenos HLA-DQ, Polimorfismo. Resumen: Clozapine is considered to be the most efficacious drug to treat schizophrenia, although it is underutilized, partially due to a side effect of agranulocytosis. This analysis of 74 candidate genes was designed to identify an association between sequence variants and clozapine-induced agranulocytosis (CIA). Link: ./index.php?lvl=notice_display&id=27970 [artículo] Candidate gene analysis identifies a polymorphism in HLA-DQB1 associated with clozapine induced agranulocytosis [texto impreso] / Maria C. Athanasiou, Autor ; Michael Dettling, Autor ; Ingolf Cascorbi, Autor . - 2022 . - pp. 458-463. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The Journal of Clinical Psychiatry > Año 2011 - Vol.72 - No. 4 (Abril) . - pp. 458-463 Palabras clave: Agranulocitosis, Antipsicóticos, Clozapina, Predisposición genética a la enfermedad, Antígenos HLA-DQ, Polimorfismo. Resumen: Clozapine is considered to be the most efficacious drug to treat schizophrenia, although it is underutilized, partially due to a side effect of agranulocytosis. This analysis of 74 candidate genes was designed to identify an association between sequence variants and clozapine-induced agranulocytosis (CIA). Link: ./index.php?lvl=notice_display&id=27970

Drug-induced agranulocytosis: Impact of different fcγ receptor polymorphisms? / Igor Mosyagin en Journal of Clinical Psychopharmacology, Año 2005 - Vol. 25 - No. 5 (Octubre)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2005 - Vol. 25 - No. 5 (Octubre) . - pp. 435-440 Título : Drug-induced agranulocytosis: Impact of different fcγ receptor polymorphisms? Tipo de documento: texto impreso Autores: Igor Mosyagin, Autor ; Ingolf Cascorbi, Autor ; Rainer Schaub, Autor Fecha de publicación: 2023 Artículo en la página: pp. 435-440 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Agranulocitosis, Agentes antipsicóticos, Agentes antitiroideos, Clozapina, Agentes fibrinolíticos, Receptores. Resumen: Drug-induced agranulocytosis is a rare but life-threatening side effect which is possibly based on immunogenetic mechanisms. Some studies regarding agranulocytosis induced by the atypical antipsychotic clozapine dealing with HLA subtyping and enzyme polymorphisms have been performed to elucidate its genetic background. Link: ./index.php?lvl=notice_display&id=30888 [artículo] Drug-induced agranulocytosis: Impact of different fcγ receptor polymorphisms? [texto impreso] / Igor Mosyagin, Autor ; Ingolf Cascorbi, Autor ; Rainer Schaub, Autor . - 2023 . - pp. 435-440. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2005 - Vol. 25 - No. 5 (Octubre) . - pp. 435-440 Palabras clave: Agranulocitosis, Agentes antipsicóticos, Agentes antitiroideos, Clozapina, Agentes fibrinolíticos, Receptores. Resumen: Drug-induced agranulocytosis is a rare but life-threatening side effect which is possibly based on immunogenetic mechanisms. Some studies regarding agranulocytosis induced by the atypical antipsychotic clozapine dealing with HLA subtyping and enzyme polymorphisms have been performed to elucidate its genetic background. Link: ./index.php?lvl=notice_display&id=30888

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