Association between citalopram serum levels and clinical improvement of patients with major depression / Haji Ostad en Journal of Clinical Psychopharmacology, Año 2011 - Vol. 31 - No. 3 (Junio)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2011 - Vol. 31 - No. 3 (Junio) . - pp. 281-286 Título : Association between citalopram serum levels and clinical improvement of patients with major depression Tipo de documento: texto impreso Autores: Haji Ostad, Autor ; Allahyari Elnaz, Autor ; André Tadic, Autor Fecha de publicación: 2022 Artículo en la página: pp. 281-286 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastorno depresivo mayor, Antidepresivo, Citalopram, Concentración sérica, Monitorización de fármacos terapéuticos Resumen: Imaging studies have shown that serum concentrations of the selective serotonin reuptake inhibitor citalopram correlate with serotonin transporter (5-HTT) occupancy in vivo. In patients with major depressive disorders treated with citalopram, 80% 5-HTT occupancy was considered to be necessary for maximal therapeutic effects, which requires citalopram serum concentrations of at least 50 ng/mL. Link: ./index.php?lvl=notice_display&id=29374 [artículo] Association between citalopram serum levels and clinical improvement of patients with major depression [texto impreso] / Haji Ostad, Autor ; Allahyari Elnaz, Autor ; André Tadic, Autor . - 2022 . - pp. 281-286. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2011 - Vol. 31 - No. 3 (Junio) . - pp. 281-286 Palabras clave: Trastorno depresivo mayor, Antidepresivo, Citalopram, Concentración sérica, Monitorización de fármacos terapéuticos Resumen: Imaging studies have shown that serum concentrations of the selective serotonin reuptake inhibitor citalopram correlate with serotonin transporter (5-HTT) occupancy in vivo. In patients with major depressive disorders treated with citalopram, 80% 5-HTT occupancy was considered to be necessary for maximal therapeutic effects, which requires citalopram serum concentrations of at least 50 ng/mL. Link: ./index.php?lvl=notice_display&id=29374

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