Decoding shared versus divergent transcriptomic signatures across cortico amygdala circuitry in ptsd and depressive disorders / Andrew E. Jaffe en The American Journal of Psychiatry, Año 2022 - Vol. 179 - No. 9 (Septiembre)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2022 - Vol. 179 - No. 9 (Septiembre) . - pp. 673-686 Título : Decoding shared versus divergent transcriptomic signatures across cortico amygdala circuitry in ptsd and depressive disorders Tipo de documento: texto impreso Autores: Andrew E. Jaffe, Autor ; Tao Ran, Autor ; Stephanie C. Page, Autor Fecha de publicación: 2022 Artículo en la página: pp. 673-686 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastorno de estrés postraumático (TEPT), Trastornos depresivos, Trastorno depresivo mayor, Tejido post mortem humano, Secuenciación de ARN Resumen: Posttraumatic stress disorder (PTSD) is a debilitating neuropsychiatric disease that is highly comorbid with major depressive disorder (MDD) and bipolar disorder. The overlap in symptoms is hypothesized to stem from partially shared genetics and underlying neurobiological mechanisms. To delineate conservation between transcriptional patterns across PTSD and MDD, the authors examined gene expression in the human cortex and amygdala in these disorders. Link: ./index.php?lvl=notice_display&id=29394 [artículo] Decoding shared versus divergent transcriptomic signatures across cortico amygdala circuitry in ptsd and depressive disorders [texto impreso] / Andrew E. Jaffe, Autor ; Tao Ran, Autor ; Stephanie C. Page, Autor . - 2022 . - pp. 673-686. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2022 - Vol. 179 - No. 9 (Septiembre) . - pp. 673-686 Palabras clave: Trastorno de estrés postraumático (TEPT), Trastornos depresivos, Trastorno depresivo mayor, Tejido post mortem humano, Secuenciación de ARN Resumen: Posttraumatic stress disorder (PTSD) is a debilitating neuropsychiatric disease that is highly comorbid with major depressive disorder (MDD) and bipolar disorder. The overlap in symptoms is hypothesized to stem from partially shared genetics and underlying neurobiological mechanisms. To delineate conservation between transcriptional patterns across PTSD and MDD, the authors examined gene expression in the human cortex and amygdala in these disorders. Link: ./index.php?lvl=notice_display&id=29394

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