Relation of serotonin transporter genetic variation to efficacy of escitalopram for generalized anxiety disorder in older adults / Eric J. Lenze en Journal of Clinical Psychopharmacology, Año 2010 - Vol. 30 - No. 6 (Diciembre)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 6 (Diciembre) . - pp. 672-677 Título : Relation of serotonin transporter genetic variation to efficacy of escitalopram for generalized anxiety disorder in older adults Tipo de documento: texto impreso Autores: Eric J. Lenze, Autor ; Alison M. Goate, Autor ; Petra Nowotny, Autor Fecha de publicación: 2022 Artículo en la página: pp. 672-677 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Geriatría, Trastornos de ansiedad, Genética, ISRS Resumen: Generalized anxiety disorder (GAD) is common in older adults and can be treated with selective serotonin reuptake inhibitors (SSRIs). Genetic variation in the serotonin transporter gene promoter region is posited to be associated with SSRI efficacy: 2 polymorphisms (5-HTTLPR S/L and rs25531 g/a) form a haplotype with the La combination having higher transcription activity than other haplotypes. Link: ./index.php?lvl=notice_display&id=29414 [artículo] Relation of serotonin transporter genetic variation to efficacy of escitalopram for generalized anxiety disorder in older adults [texto impreso] / Eric J. Lenze, Autor ; Alison M. Goate, Autor ; Petra Nowotny, Autor . - 2022 . - pp. 672-677. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 6 (Diciembre) . - pp. 672-677 Palabras clave: Geriatría, Trastornos de ansiedad, Genética, ISRS Resumen: Generalized anxiety disorder (GAD) is common in older adults and can be treated with selective serotonin reuptake inhibitors (SSRIs). Genetic variation in the serotonin transporter gene promoter region is posited to be associated with SSRI efficacy: 2 polymorphisms (5-HTTLPR S/L and rs25531 g/a) form a haplotype with the La combination having higher transcription activity than other haplotypes. Link: ./index.php?lvl=notice_display&id=29414

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