Biblioteca Humberto Rosselli Quijano
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[artículo]
| Título : |
Evaluation of the abuse potential of extended release hydromorphone versus immediate release hydromorphone |
| Tipo de documento: |
texto impreso |
| Autores: |
Megan J. Shram, Autor ; Gayatri Sathyan, Autor ; Sarita Khanna, Autor |
| Fecha de publicación: |
2022 |
| Artículo en la página: |
pp. 25-33 |
| Idioma : |
Inglés (eng) Idioma original : Inglés (eng) |
| Palabras clave: |
Hidromorfona, Potencial de abuso, Liberación prolongada, Test - retest |
| Resumen: |
Immediate release (IR) hydromorphone has experienced significant misuse and abuse. An extended release (ER) hydromorphone formulation has been developed to provide sustained pain relief and may reduce the likelihood for abuse by delaying absorption. In this double-blind, placebo-controlled, randomized, 2-part crossover study, the abuse potential of single oral doses of hydromorphone ER (intact: 16-, 32-, and 64-mg; milled: 8-mg) was compared with 8-mg hydromorphone IR and placebo. |
| Link: |
./index.php?lvl=notice_display&id=29467 |
in Journal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 1 (Febrero) . - pp. 25-33
[artículo] Evaluation of the abuse potential of extended release hydromorphone versus immediate release hydromorphone [texto impreso] / Megan J. Shram, Autor ; Gayatri Sathyan, Autor ; Sarita Khanna, Autor . - 2022 . - pp. 25-33. Idioma : Inglés ( eng) Idioma original : Inglés ( eng) in Journal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 1 (Febrero) . - pp. 25-33
| Palabras clave: |
Hidromorfona, Potencial de abuso, Liberación prolongada, Test - retest |
| Resumen: |
Immediate release (IR) hydromorphone has experienced significant misuse and abuse. An extended release (ER) hydromorphone formulation has been developed to provide sustained pain relief and may reduce the likelihood for abuse by delaying absorption. In this double-blind, placebo-controlled, randomized, 2-part crossover study, the abuse potential of single oral doses of hydromorphone ER (intact: 16-, 32-, and 64-mg; milled: 8-mg) was compared with 8-mg hydromorphone IR and placebo. |
| Link: |
./index.php?lvl=notice_display&id=29467 |
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