Artículos

Psychiatric genetics begins to find its footing / Jordan W. Smoller en The American Journal of Psychiatry, Año 2019 - Vol. 176 - No.8 (Agosto)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2019 - Vol. 176 - No.8 (Agosto) . - pp. 609-614 Título : Psychiatric genetics begins to find its footing Tipo de documento: texto impreso Autores: Jordan W. Smoller, Autor Fecha de publicación: 2019 Artículo en la página: pp. 609-614 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Genética, Depresión, Esquizofrenia, Trastorno bipolar, Trastorno del espectro autista, Suicidio Resumen: It has often been said that our understanding of the genetic basis of psychiatric disorders is still in its infancy. But today, it is fair to say that the field of psychiatric genetics has finally learned to walk. Link: ./index.php?lvl=notice_display&id=20992 [artículo] Psychiatric genetics begins to find its footing [texto impreso] / Jordan W. Smoller, Autor . - 2019 . - pp. 609-614. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2019 - Vol. 176 - No.8 (Agosto) . - pp. 609-614 Palabras clave: Genética, Depresión, Esquizofrenia, Trastorno bipolar, Trastorno del espectro autista, Suicidio Resumen: It has often been said that our understanding of the genetic basis of psychiatric disorders is still in its infancy. But today, it is fair to say that the field of psychiatric genetics has finally learned to walk. Link: ./index.php?lvl=notice_display&id=20992

Polygenic risk / Thorhildur Halldorsdottir en The American Journal of Psychiatry, Año 2019 - Vol. 176 - No.8 (Agosto)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2019 - Vol. 176 - No.8 (Agosto) . - pp. 615-625 Título : Polygenic risk : predicting depression outcomes in clinical and epidemiological cohorts of youths Tipo de documento: texto impreso Autores: Thorhildur Halldorsdottir, Autor ; Charlotte Piechaczek, Autor ; Ana Paula Soares de Matos, Autor Fecha de publicación: 2019 Artículo en la página: pp. 615-625 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Prevención, Trastornos del estado de ánimo - unipolar, Depresión de inicio temprano, Riesgo poligénico, Juventud en riesgo, Abuso infantil Resumen: Identifying risk factors for major depression and depressive symptoms in youths could have important implications for prevention efforts. This study examined the association of polygenic risk scores (PRSs) for a broad depression phenotype derived from a large-scale genome-wide association study (GWAS) in adults,... Link: ./index.php?lvl=notice_display&id=20993 [artículo] Polygenic risk : predicting depression outcomes in clinical and epidemiological cohorts of youths [texto impreso] / Thorhildur Halldorsdottir, Autor ; Charlotte Piechaczek, Autor ; Ana Paula Soares de Matos, Autor . - 2019 . - pp. 615-625. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2019 - Vol. 176 - No.8 (Agosto) . - pp. 615-625 Palabras clave: Prevención, Trastornos del estado de ánimo - unipolar, Depresión de inicio temprano, Riesgo poligénico, Juventud en riesgo, Abuso infantil Resumen: Identifying risk factors for major depression and depressive symptoms in youths could have important implications for prevention efforts. This study examined the association of polygenic risk scores (PRSs) for a broad depression phenotype derived from a large-scale genome-wide association study (GWAS) in adults,... Link: ./index.php?lvl=notice_display&id=20993

Neurobiology of self-regulation / Thorhildur Halldorsdottir en The American Journal of Psychiatry, Año 2019 - Vol. 176 - No.8 (Agosto)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2019 - Vol. 176 - No.8 (Agosto) . - pp. 626-634 Título : Neurobiology of self-regulation : longitudinal influence of fkbp5 and intimate partner violence on emotional and cognitive development in childhood Tipo de documento: texto impreso Autores: Thorhildur Halldorsdottir, Autor ; Dunja Kurtoic, Autor ; Bertram Müller-Myhsok, Autor Fecha de publicación: 2019 Artículo en la página: pp. 626-634 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Estrés temprano en la vida, Autorregulación, FKBP5, Gen por medio ambiente, Marcador biológico, Violencia de pareja Resumen: Self-regulation includes the volitional and nonvolitional regulation of emotional, cognitive, and physiological responses to stimulation. It develops from infancy through individual characteristics and the environment, with the stress hormone system as a central player. Link: ./index.php?lvl=notice_display&id=20994 [artículo] Neurobiology of self-regulation : longitudinal influence of fkbp5 and intimate partner violence on emotional and cognitive development in childhood [texto impreso] / Thorhildur Halldorsdottir, Autor ; Dunja Kurtoic, Autor ; Bertram Müller-Myhsok, Autor . - 2019 . - pp. 626-634. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2019 - Vol. 176 - No.8 (Agosto) . - pp. 626-634 Palabras clave: Estrés temprano en la vida, Autorregulación, FKBP5, Gen por medio ambiente, Marcador biológico, Violencia de pareja Resumen: Self-regulation includes the volitional and nonvolitional regulation of emotional, cognitive, and physiological responses to stimulation. It develops from infancy through individual characteristics and the environment, with the stress hormone system as a central player. Link: ./index.php?lvl=notice_display&id=20994

Identifying novel types of irritability using a developmental genetic approach / Lucy Riglin en The American Journal of Psychiatry, Año 2019 - Vol. 176 - No.8 (Agosto)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2019 - Vol. 176 - No.8 (Agosto) . - pp. 635-642 Título : Identifying novel types of irritability using a developmental genetic approach Tipo de documento: texto impreso Autores: Lucy Riglin, Autor ; Olga Eyre, Autor ; Ajay K. Thapar, Autor Fecha de publicación: 2019 Artículo en la página: pp. 635-642 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Psiquiatría infantil, Diagnóstico y clasificación, Irritabilidad, Longitudinal, Genético, Puntuaciones de riesgo poligénico, ALSPAC Resumen: Irritability, which is strongly associated with impairment and negative outcomes, is a common reason for referral to mental health services but is a nosological and treatment challenge. A major issue is how irritability should be conceptualized. Link: ./index.php?lvl=notice_display&id=20995 [artículo] Identifying novel types of irritability using a developmental genetic approach [texto impreso] / Lucy Riglin, Autor ; Olga Eyre, Autor ; Ajay K. Thapar, Autor . - 2019 . - pp. 635-642. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2019 - Vol. 176 - No.8 (Agosto) . - pp. 635-642 Palabras clave: Psiquiatría infantil, Diagnóstico y clasificación, Irritabilidad, Longitudinal, Genético, Puntuaciones de riesgo poligénico, ALSPAC Resumen: Irritability, which is strongly associated with impairment and negative outcomes, is a common reason for referral to mental health services but is a nosological and treatment challenge. A major issue is how irritability should be conceptualized. Link: ./index.php?lvl=notice_display&id=20995

A third linear association between olduvai (duf1220) copy number and severity of the classic symptoms of inherited autism / Jonathan M. Davis en The American Journal of Psychiatry, Año 2019 - Vol. 176 - No.8 (Agosto)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2019 - Vol. 176 - No.8 (Agosto) . - pp. 643-650 Título : A third linear association between olduvai (duf1220) copy number and severity of the classic symptoms of inherited autism Tipo de documento: texto impreso Autores: Jonathan M. Davis, Autor ; Ilea Heft, Autor ; Stephen W. Scherer, Autor Fecha de publicación: 2019 Artículo en la página: pp. 643-650 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Olduvai, DUF1220, Síntomas de autismo, Número de copia Resumen: The authors previously reported that the copy number of sequences encoding an Olduvai protein domain subtype (CON1) shows a linear association with the severity of social deficits and communication impairment in individuals with autism. Link: ./index.php?lvl=notice_display&id=20996 [artículo] A third linear association between olduvai (duf1220) copy number and severity of the classic symptoms of inherited autism [texto impreso] / Jonathan M. Davis, Autor ; Ilea Heft, Autor ; Stephen W. Scherer, Autor . - 2019 . - pp. 643-650. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2019 - Vol. 176 - No.8 (Agosto) . - pp. 643-650 Palabras clave: Olduvai, DUF1220, Síntomas de autismo, Número de copia Resumen: The authors previously reported that the copy number of sequences encoding an Olduvai protein domain subtype (CON1) shows a linear association with the severity of social deficits and communication impairment in individuals with autism. Link: ./index.php?lvl=notice_display&id=20996

Gwas of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores / Niamh Mullins en The American Journal of Psychiatry, Año 2019 - Vol. 176 - No.8 (Agosto)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2019 - Vol. 176 - No.8 (Agosto) . - pp. 651-660 Título : Gwas of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores Tipo de documento: texto impreso Autores: Niamh Mullins, Autor ; Tim B. Bigdeli, Autor ; Anders D. Børglum, Autor Fecha de publicación: 2019 Artículo en la página: pp. 651-660 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Estudio de asociación de genoma completo, Suicidio, Puntuación de riesgo poligénico, Trastornos del estado de ánimo, Esquizofrenia, Consorcio de Genómica Psiquiátrica Resumen: More than 90% of people who attempt suicide have a psychiatric diagnosis; however, twin and family studies suggest that the genetic etiology of suicide attempt is partially distinct from that of the psychiatric disorders themselves. Link: ./index.php?lvl=notice_display&id=20997 [artículo] Gwas of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores [texto impreso] / Niamh Mullins, Autor ; Tim B. Bigdeli, Autor ; Anders D. Børglum, Autor . - 2019 . - pp. 651-660. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2019 - Vol. 176 - No.8 (Agosto) . - pp. 651-660 Palabras clave: Estudio de asociación de genoma completo, Suicidio, Puntuación de riesgo poligénico, Trastornos del estado de ánimo, Esquizofrenia, Consorcio de Genómica Psiquiátrica Resumen: More than 90% of people who attempt suicide have a psychiatric diagnosis; however, twin and family studies suggest that the genetic etiology of suicide attempt is partially distinct from that of the psychiatric disorders themselves. Link: ./index.php?lvl=notice_display&id=20997

The relationship between common variant schizophrenia liability and number of offspring in the uk biobank / Valentina Escott-Price en The American Journal of Psychiatry, Año 2019 - Vol. 176 - No.8 (Agosto)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2019 - Vol. 176 - No.8 (Agosto) . - pp. 661-666 Título : The relationship between common variant schizophrenia liability and number of offspring in the uk biobank Tipo de documento: texto impreso Autores: Valentina Escott-Price, Autor ; Antonio F. Pardiñas, Autor ; Enrique Santiago, Autor Fecha de publicación: 2019 Artículo en la página: pp. 661-666 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Esquizofrenia, Genética, Fecundidad, Estadística Resumen: Schizophrenia is associated with a marked reduction in reproductive success, yet alleles that are common contribute substantially to the liability of the disorder. Among several possible explanations for this, it has been postulated that individuals who carry risk alleles but are unaffected are at some reproductive advantage,... Link: ./index.php?lvl=notice_display&id=20998 [artículo] The relationship between common variant schizophrenia liability and number of offspring in the uk biobank [texto impreso] / Valentina Escott-Price, Autor ; Antonio F. Pardiñas, Autor ; Enrique Santiago, Autor . - 2019 . - pp. 661-666. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2019 - Vol. 176 - No.8 (Agosto) . - pp. 661-666 Palabras clave: Esquizofrenia, Genética, Fecundidad, Estadística Resumen: Schizophrenia is associated with a marked reduction in reproductive success, yet alleles that are common contribute substantially to the liability of the disorder. Among several possible explanations for this, it has been postulated that individuals who carry risk alleles but are unaffected are at some reproductive advantage,... Link: ./index.php?lvl=notice_display&id=20998