Quetiapine versus placebo in combination with lithium or divalproex for the treatment of bipolar mania / Lakshmi N. Yatham en Journal of Clinical Psychopharmacology, Año 2004 - Vol. 24 - No. 6 (Diciembre)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 6 (Diciembre) . - pp. 599-606 Título : Quetiapine versus placebo in combination with lithium or divalproex for the treatment of bipolar mania Tipo de documento: texto impreso Autores: Lakshmi N. Yatham, Autor ; Björn Paulsson, Autor ; Jamie Mullen, Autor Fecha de publicación: 2023 Artículo en la página: pp. 599-606 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastorno bipolar, Dibenzotiacepinas, Terapia con medicamentos, Litio, Fumarato de quetiapina, Ácido Valproico. Resumen: Quetiapine (QTP) combined with lithium (Li) or divalproex (DVP) for the treatment of mania was evaluated in 2 double-blind, placebo-controlled studies. Patients were randomized to 3 or 6 weeks of treatment with QTP plus Li/DVP or placebo (PBO) plus Li/DVP. Quetiapine was dosed up to 800 mg/d; Li was dosed to achieve serum concentrations of 0.7-1.0 mEq/L and DVP to 50-100 μg/mL. Link: ./index.php?lvl=notice_display&id=30931 [artículo] Quetiapine versus placebo in combination with lithium or divalproex for the treatment of bipolar mania [texto impreso] / Lakshmi N. Yatham, Autor ; Björn Paulsson, Autor ; Jamie Mullen, Autor . - 2023 . - pp. 599-606. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 6 (Diciembre) . - pp. 599-606 Palabras clave: Trastorno bipolar, Dibenzotiacepinas, Terapia con medicamentos, Litio, Fumarato de quetiapina, Ácido Valproico. Resumen: Quetiapine (QTP) combined with lithium (Li) or divalproex (DVP) for the treatment of mania was evaluated in 2 double-blind, placebo-controlled studies. Patients were randomized to 3 or 6 weeks of treatment with QTP plus Li/DVP or placebo (PBO) plus Li/DVP. Quetiapine was dosed up to 800 mg/d; Li was dosed to achieve serum concentrations of 0.7-1.0 mEq/L and DVP to 50-100 μg/mL. Link: ./index.php?lvl=notice_display&id=30931

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