Chronic lithium administration enhances noradrenergic responses to intravenous administration of the α2 antagonist idazoxan in healthy volunteers / Aysegül Özerdem en Journal of Clinical Psychopharmacology, Año 2004 - Vol. 24 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 150-154 Título : Chronic lithium administration enhances noradrenergic responses to intravenous administration of the α2 antagonist idazoxan in healthy volunteers Tipo de documento: texto impreso Autores: Aysegül Özerdem, Autor ; Mark E. Schmidt, Autor ; Husseini K. Manji, Autor Fecha de publicación: 2023 Artículo en la página: pp. 150-154 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antagonistas alfa adrenérgicos, Agentes antimaníacos, Hemodinámica, Idazoxano, Carbonato de litio, Noradrenalina, Características sexuales Resumen: The acute and chronic effects of lithium carbonate administration at therapeutic blood levels on peripheral noradrenergic activity and sympathetic responses to α2 adrenoceptor blockade were examined in 10 medically and psychiatrically healthy volunteers. Supine resting levels of plasma norepinephrine and the increases in norepinephrine following intravenous infusion of 200 μg/kg of idazoxan, a selective α2 adrenoceptor antagonist, were determined before lithium (Li+) administration and after 5 days and after 4 weeks of daily Li+ treatment. Link: ./index.php?lvl=notice_display&id=30963 [artículo] Chronic lithium administration enhances noradrenergic responses to intravenous administration of the α2 antagonist idazoxan in healthy volunteers [texto impreso] / Aysegül Özerdem, Autor ; Mark E. Schmidt, Autor ; Husseini K. Manji, Autor . - 2023 . - pp. 150-154. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 2 (Abril) . - pp. 150-154 Palabras clave: Antagonistas alfa adrenérgicos, Agentes antimaníacos, Hemodinámica, Idazoxano, Carbonato de litio, Noradrenalina, Características sexuales Resumen: The acute and chronic effects of lithium carbonate administration at therapeutic blood levels on peripheral noradrenergic activity and sympathetic responses to α2 adrenoceptor blockade were examined in 10 medically and psychiatrically healthy volunteers. Supine resting levels of plasma norepinephrine and the increases in norepinephrine following intravenous infusion of 200 μg/kg of idazoxan, a selective α2 adrenoceptor antagonist, were determined before lithium (Li+) administration and after 5 days and after 4 weeks of daily Li+ treatment. Link: ./index.php?lvl=notice_display&id=30963

---

1 (1 - 1 / 1)