Comparative CYP3A4 inhibitory effects of venlafaxine, fluoxetine, sertraline, and nefazodone in healthy volunteers / C. Lindsay DeVane en Journal of Clinical Psychopharmacology, Año 2004 - Vol. 24 - No. 1 (Febrero)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 1 (Febrero) . - pp. 4-10 Título : Comparative CYP3A4 inhibitory effects of venlafaxine, fluoxetine, sertraline, and nefazodone in healthy volunteers Tipo de documento: texto impreso Autores: C. Lindsay DeVane, Autor ; Jennifer L. Donovan, Autor ; Heidi L. Liston, Autor Fecha de publicación: 2023 Artículo en la página: pp. 4-10 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Radioisótopos de carbono, Ciclohexanoles, Inhibidores de la enzima citocromo P-450, Sistema enzimático citocromo P-450, Eritromicina, Fluoxetina, Piperazinas, Sertralina. Resumen: An antidepressant for use in the patient receiving concomitant drug treatment, over-the-counter medications, or herbal products should lack cytochrome P-450 (CYP) 3A4 inductive or inhibitory activity to provide the least likelihood of a drug-drug interaction. This study addresses the potential of 4 diverse antidepressants (venlafaxine, nefazodone, sertraline, and fluoxetine) to inhibit or induce CYP3A4. Link: ./index.php?lvl=notice_display&id=30971 [artículo] Comparative CYP3A4 inhibitory effects of venlafaxine, fluoxetine, sertraline, and nefazodone in healthy volunteers [texto impreso] / C. Lindsay DeVane, Autor ; Jennifer L. Donovan, Autor ; Heidi L. Liston, Autor . - 2023 . - pp. 4-10. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 1 (Febrero) . - pp. 4-10 Palabras clave: Radioisótopos de carbono, Ciclohexanoles, Inhibidores de la enzima citocromo P-450, Sistema enzimático citocromo P-450, Eritromicina, Fluoxetina, Piperazinas, Sertralina. Resumen: An antidepressant for use in the patient receiving concomitant drug treatment, over-the-counter medications, or herbal products should lack cytochrome P-450 (CYP) 3A4 inductive or inhibitory activity to provide the least likelihood of a drug-drug interaction. This study addresses the potential of 4 diverse antidepressants (venlafaxine, nefazodone, sertraline, and fluoxetine) to inhibit or induce CYP3A4. Link: ./index.php?lvl=notice_display&id=30971

Differential time course of cytochrome p450 2d6 enzyme inhibition by fluoxetine, sertraline, and paroxetine in healthy volunteers / Heidi L. Liston en Journal of Clinical Psychopharmacology, Año 2002 - Vol. 22 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2002 - Vol. 22 - No. 2 (Abril) . - pp. 169-173 Título : Differential time course of cytochrome p450 2d6 enzyme inhibition by fluoxetine, sertraline, and paroxetine in healthy volunteers Tipo de documento: texto impreso Autores: Heidi L. Liston, Autor ; C. Lindsay DeVane, Autor ; David W. Boulton, Autor Fecha de publicación: 2023 Artículo en la página: pp. 169-173 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Inhibidores del citocromo P-450 CYP2D6, Fluoxetina, Paroxetina, Inhibidores selectivos de la recaptación de serotonina, Sertralina, Síndrome de abstinencia de sustancias. Resumen: The selective serotonin reuptake inhibitors (SSRIs) paroxetine, sertraline, and fluoxetine have varying degrees of potency in inhibiting the hepatic cytochrome P450 (CYP) 2D6 enzyme. However, the time course for maximum inhibition to occur or for inhibition to dissipate when dosing is discontinued, requires clarification. In an open label, parallel group study of 45 healthy volunteers, the time course of CYP2D6 inhibition of the above SSRIs was evaluated. Link: ./index.php?lvl=notice_display&id=31082 [artículo] Differential time course of cytochrome p450 2d6 enzyme inhibition by fluoxetine, sertraline, and paroxetine in healthy volunteers [texto impreso] / Heidi L. Liston, Autor ; C. Lindsay DeVane, Autor ; David W. Boulton, Autor . - 2023 . - pp. 169-173. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2002 - Vol. 22 - No. 2 (Abril) . - pp. 169-173 Palabras clave: Inhibidores del citocromo P-450 CYP2D6, Fluoxetina, Paroxetina, Inhibidores selectivos de la recaptación de serotonina, Sertralina, Síndrome de abstinencia de sustancias. Resumen: The selective serotonin reuptake inhibitors (SSRIs) paroxetine, sertraline, and fluoxetine have varying degrees of potency in inhibiting the hepatic cytochrome P450 (CYP) 2D6 enzyme. However, the time course for maximum inhibition to occur or for inhibition to dissipate when dosing is discontinued, requires clarification. In an open label, parallel group study of 45 healthy volunteers, the time course of CYP2D6 inhibition of the above SSRIs was evaluated. Link: ./index.php?lvl=notice_display&id=31082

Drug glucuronidation in clinical psychopharmacology / Heidi L. Liston en Journal of Clinical Psychopharmacology, Año 2001 - Vol. 21 - No. 5 (Octubre)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 5 (Octubre) . - pp. 500-515 Título : Drug glucuronidation in clinical psychopharmacology Tipo de documento: texto impreso Autores: Heidi L. Liston, Autor ; John C. Markowitz, Autor ; C. Lindsay DeVane, Autor Fecha de publicación: 2023 Artículo en la página: pp. 500-515 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Sistema enzimático citocromo P-450, Interacción medicamentosa, Trastornos mentales, Psicofarmacología, Medicamentos psicotrópicos. Resumen: Glucuronidation is a phase II metabolic process and one of the most common pathways in the formation of hydrophilic drug metabolites. At least 33 families of uridine diphosphate-glucuronosyltransferases have been identified in vitro, and specific nomenclature similar to that used to classify the cytochrome (CYP) P450 system has been established. Link: ./index.php?lvl=notice_display&id=31113 [artículo] Drug glucuronidation in clinical psychopharmacology [texto impreso] / Heidi L. Liston, Autor ; John C. Markowitz, Autor ; C. Lindsay DeVane, Autor . - 2023 . - pp. 500-515. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 5 (Octubre) . - pp. 500-515 Palabras clave: Sistema enzimático citocromo P-450, Interacción medicamentosa, Trastornos mentales, Psicofarmacología, Medicamentos psicotrópicos. Resumen: Glucuronidation is a phase II metabolic process and one of the most common pathways in the formation of hydrophilic drug metabolites. At least 33 families of uridine diphosphate-glucuronosyltransferases have been identified in vitro, and specific nomenclature similar to that used to classify the cytochrome (CYP) P450 system has been established. Link: ./index.php?lvl=notice_display&id=31113

Single dose pharmacokinetics of methylphenidate in CYP2D6 extensive and poor metabolizers / C. Lindsay DeVane en Journal of Clinical Psychopharmacology, Año 2000 - Vol. 20 - No. 3 (Junio)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 347-349 Título : Single dose pharmacokinetics of methylphenidate in CYP2D6 extensive and poor metabolizers Tipo de documento: texto impreso Autores: C. Lindsay DeVane, Autor ; John C. Markowitz, Autor ; Stanley W. Carson, Autor Fecha de publicación: 2023 Artículo en la página: pp. 347-349 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Estimulantes del sistema nervioso central, Citocromo P-450 CYP2D6, Inhibidores del citocromo P-450 CYP2D6, Espectrometría de masas, Metilfenidato. Resumen: Six adults phenotyped as either extensive (N = 4) or poor (N = 2) metabolizers for cytochrome P450 (CYP) 2D6 were given a 10-mg oral dose of methylphenidate (MPH) on two separate occasions with and without quinidine, a potent CYP2D6 inhibitor. Quinidine had no significant effect on the pharmacokinetics of either MPH or ritalinic acid, its major metabolite, in either group of CYP2D6 metabolizers. Link: ./index.php?lvl=notice_display&id=31193 [artículo] Single dose pharmacokinetics of methylphenidate in CYP2D6 extensive and poor metabolizers [texto impreso] / C. Lindsay DeVane, Autor ; John C. Markowitz, Autor ; Stanley W. Carson, Autor . - 2023 . - pp. 347-349. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 347-349 Palabras clave: Estimulantes del sistema nervioso central, Citocromo P-450 CYP2D6, Inhibidores del citocromo P-450 CYP2D6, Espectrometría de masas, Metilfenidato. Resumen: Six adults phenotyped as either extensive (N = 4) or poor (N = 2) metabolizers for cytochrome P450 (CYP) 2D6 were given a 10-mg oral dose of methylphenidate (MPH) on two separate occasions with and without quinidine, a potent CYP2D6 inhibitor. Quinidine had no significant effect on the pharmacokinetics of either MPH or ritalinic acid, its major metabolite, in either group of CYP2D6 metabolizers. Link: ./index.php?lvl=notice_display&id=31193

Single-dose pharmacokinetics of methylphenidate in cyp2d6 extensive and poor metabolizers / C. Lindsay DeVane en Journal of Clinical Psychopharmacology, Año 2000 - Vol. 20 - No. 3 (Junio)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 347-349 Título : Single-dose pharmacokinetics of methylphenidate in cyp2d6 extensive and poor metabolizers Tipo de documento: texto impreso Autores: C. Lindsay DeVane, Autor ; John S. Markowitz, Autor ; Stanley W. Carson, Autor Fecha de publicación: 2023 Artículo en la página: pp. 347-349 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Estimulantes del sistema nervioso central, Citocromo P-450 CYP2D6, Espectrometría de masas, Metilfenidato. Resumen: Six adults phenotyped as either extensive (N = 4) or poor (N = 2) metabolizers for cytochrome P450 (CYP) 2D6 were given a 10-mg oral dose of methylphenidate (MPH) on two separate occasions with and without quinidine, a potent CYP2D6 inhibitor. Quinidine had no significant effect on the pharmacokinetics of either MPH or ritalinic acid, its major metabolite, in either group of CYP2D6 metabolizers. Link: ./index.php?lvl=notice_display&id=31202 [artículo] Single-dose pharmacokinetics of methylphenidate in cyp2d6 extensive and poor metabolizers [texto impreso] / C. Lindsay DeVane, Autor ; John S. Markowitz, Autor ; Stanley W. Carson, Autor . - 2023 . - pp. 347-349. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 347-349 Palabras clave: Estimulantes del sistema nervioso central, Citocromo P-450 CYP2D6, Espectrometría de masas, Metilfenidato. Resumen: Six adults phenotyped as either extensive (N = 4) or poor (N = 2) metabolizers for cytochrome P450 (CYP) 2D6 were given a 10-mg oral dose of methylphenidate (MPH) on two separate occasions with and without quinidine, a potent CYP2D6 inhibitor. Quinidine had no significant effect on the pharmacokinetics of either MPH or ritalinic acid, its major metabolite, in either group of CYP2D6 metabolizers. Link: ./index.php?lvl=notice_display&id=31202

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