A typological model for estimation of drug and placebo effects in depression / Donald C. Ross en Journal of Clinical Psychopharmacology, Año 2002 - Vol. 22 - No. 4 (Agosto)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2002 - Vol. 22 - No. 4 (Agosto) . - pp. 414-418 Título : A typological model for estimation of drug and placebo effects in depression Tipo de documento: texto impreso Autores: Donald C. Ross, Autor ; Frederic Quitkin, Autor ; Donald F. Klein, Autor Fecha de publicación: 2023 Artículo en la página: pp. 414-418 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antidepresivos, Ensayos clínicos, Trastorno depresivo mayor, Fluoxetina, Imipramina. Resumen: One reason for failure to find specific treatment effects in drug versus placebo trials with patients who have depression is an insufficient period of observation. Also, differentiating between early fleeting response and maintained response has been shown relevant to detecting specific drug action. A model in which various types of drug and placebo response are specifically stipulated and which takes advantage of a two-stage experimental design is proposed. Link: ./index.php?lvl=notice_display&id=31059 [artículo] A typological model for estimation of drug and placebo effects in depression [texto impreso] / Donald C. Ross, Autor ; Frederic Quitkin, Autor ; Donald F. Klein, Autor . - 2023 . - pp. 414-418. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2002 - Vol. 22 - No. 4 (Agosto) . - pp. 414-418 Palabras clave: Antidepresivos, Ensayos clínicos, Trastorno depresivo mayor, Fluoxetina, Imipramina. Resumen: One reason for failure to find specific treatment effects in drug versus placebo trials with patients who have depression is an insufficient period of observation. Also, differentiating between early fleeting response and maintained response has been shown relevant to detecting specific drug action. A model in which various types of drug and placebo response are specifically stipulated and which takes advantage of a two-stage experimental design is proposed. Link: ./index.php?lvl=notice_display&id=31059

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