Differential time course of cytochrome p450 2d6 enzyme inhibition by fluoxetine, sertraline, and paroxetine in healthy volunteers / Heidi L. Liston en Journal of Clinical Psychopharmacology, Año 2002 - Vol. 22 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2002 - Vol. 22 - No. 2 (Abril) . - pp. 169-173 Título : Differential time course of cytochrome p450 2d6 enzyme inhibition by fluoxetine, sertraline, and paroxetine in healthy volunteers Tipo de documento: texto impreso Autores: Heidi L. Liston, Autor ; C. Lindsay DeVane, Autor ; David W. Boulton, Autor Fecha de publicación: 2023 Artículo en la página: pp. 169-173 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Inhibidores del citocromo P-450 CYP2D6, Fluoxetina, Paroxetina, Inhibidores selectivos de la recaptación de serotonina, Sertralina, Síndrome de abstinencia de sustancias. Resumen: The selective serotonin reuptake inhibitors (SSRIs) paroxetine, sertraline, and fluoxetine have varying degrees of potency in inhibiting the hepatic cytochrome P450 (CYP) 2D6 enzyme. However, the time course for maximum inhibition to occur or for inhibition to dissipate when dosing is discontinued, requires clarification. In an open label, parallel group study of 45 healthy volunteers, the time course of CYP2D6 inhibition of the above SSRIs was evaluated. Link: ./index.php?lvl=notice_display&id=31082 [artículo] Differential time course of cytochrome p450 2d6 enzyme inhibition by fluoxetine, sertraline, and paroxetine in healthy volunteers [texto impreso] / Heidi L. Liston, Autor ; C. Lindsay DeVane, Autor ; David W. Boulton, Autor . - 2023 . - pp. 169-173. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2002 - Vol. 22 - No. 2 (Abril) . - pp. 169-173 Palabras clave: Inhibidores del citocromo P-450 CYP2D6, Fluoxetina, Paroxetina, Inhibidores selectivos de la recaptación de serotonina, Sertralina, Síndrome de abstinencia de sustancias. Resumen: The selective serotonin reuptake inhibitors (SSRIs) paroxetine, sertraline, and fluoxetine have varying degrees of potency in inhibiting the hepatic cytochrome P450 (CYP) 2D6 enzyme. However, the time course for maximum inhibition to occur or for inhibition to dissipate when dosing is discontinued, requires clarification. In an open label, parallel group study of 45 healthy volunteers, the time course of CYP2D6 inhibition of the above SSRIs was evaluated. Link: ./index.php?lvl=notice_display&id=31082

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