Placebo-controlled comparison of three dose-regimens of 5-hydroxytryptophan challenge test in healthy volunteers / Harm J. Gijsman en Journal of Clinical Psychopharmacology, Año 2002 - Vol. 22 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2002 - Vol. 22 - No. 2 (Abril) . - pp. 183-189 Título : Placebo-controlled comparison of three dose-regimens of 5-hydroxytryptophan challenge test in healthy volunteers Tipo de documento: texto impreso Autores: Harm J. Gijsman, Autor ; Joop M. A. van Gerven, Autor ; Marieke L. de Kam, Autor Fecha de publicación: 2023 Artículo en la página: pp. 183-189 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Carbidopa, Hidrocortisona, Receptores presinápticos, Serotonina. Resumen: Single-dose administration of 5-hydroxytryptophan (5-HTP) is regularly used as a challenge test of the serotonergic system. The use of 5-HTP has been limited by an apparent small window between the occurrence of neuroendocrine endpoints and the occurrence of side effects. Therefore, many dosing strategies have been tried with and without concurrent administration of carbidopa, a peripheral inhibitor of the decarboxylation from 5-HTP to serotonin. Link: ./index.php?lvl=notice_display&id=31084 [artículo] Placebo-controlled comparison of three dose-regimens of 5-hydroxytryptophan challenge test in healthy volunteers [texto impreso] / Harm J. Gijsman, Autor ; Joop M. A. van Gerven, Autor ; Marieke L. de Kam, Autor . - 2023 . - pp. 183-189. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2002 - Vol. 22 - No. 2 (Abril) . - pp. 183-189 Palabras clave: Carbidopa, Hidrocortisona, Receptores presinápticos, Serotonina. Resumen: Single-dose administration of 5-hydroxytryptophan (5-HTP) is regularly used as a challenge test of the serotonergic system. The use of 5-HTP has been limited by an apparent small window between the occurrence of neuroendocrine endpoints and the occurrence of side effects. Therefore, many dosing strategies have been tried with and without concurrent administration of carbidopa, a peripheral inhibitor of the decarboxylation from 5-HTP to serotonin. Link: ./index.php?lvl=notice_display&id=31084

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