Are lorazepam-induced deficits in attention similar to those resulting from aging? / Emma Fluck en Journal of Clinical Psychopharmacology, Año 2001 - Vol. 21 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 126-130 Título : Are lorazepam-induced deficits in attention similar to those resulting from aging? Tipo de documento: texto impreso Autores: Emma Fluck, Autor ; Cathy Fernandes, Autor ; Sandra E. File, Autor Fecha de publicación: 2023 Artículo en la página: pp. 126-130 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Envejecimiento, Atención, Moduladores GABA, Lorazepam. Resumen: The purpose of this experiment was to compare, in three tasks of attention, the impairment caused by lorazepam (1 and 2.5 mg) administered to young volunteers with the impairment that results from aging. Performance on digit cancellation (DC), digit-symbol substitution (DSS), and Paced Auditory Serial Addition Task (PASAT) was significantly impaired by lorazepam (2.5 mg) and was significantly worse in the middle-aged group (mean ± SEM, aged 58.9 ± 0.8 years) compared with the younger, IQ-matched group (20.7 ± 0.2 years). Link: ./index.php?lvl=notice_display&id=31115 [artículo] Are lorazepam-induced deficits in attention similar to those resulting from aging? [texto impreso] / Emma Fluck, Autor ; Cathy Fernandes, Autor ; Sandra E. File, Autor . - 2023 . - pp. 126-130. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 126-130 Palabras clave: Envejecimiento, Atención, Moduladores GABA, Lorazepam. Resumen: The purpose of this experiment was to compare, in three tasks of attention, the impairment caused by lorazepam (1 and 2.5 mg) administered to young volunteers with the impairment that results from aging. Performance on digit cancellation (DC), digit-symbol substitution (DSS), and Paced Auditory Serial Addition Task (PASAT) was significantly impaired by lorazepam (2.5 mg) and was significantly worse in the middle-aged group (mean ± SEM, aged 58.9 ± 0.8 years) compared with the younger, IQ-matched group (20.7 ± 0.2 years). Link: ./index.php?lvl=notice_display&id=31115

Cognitive effects of 10 years of hormone-replacement therapy with tibolone / Emma Fluck en Journal of Clinical Psychopharmacology, Año 2002 - Vol. 22 - No. 2 (Febrero)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2002 - Vol. 22 - No. 2 (Febrero) . - pp. 62-67 Título : Cognitive effects of 10 years of hormone-replacement therapy with tibolone Tipo de documento: texto impreso Autores: Emma Fluck, Autor ; Sandra E. File, Autor ; Janice Rymer, Autor Fecha de publicación: 2023 Artículo en la página: pp. 62-67 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Efectos climatéricos, Climatérico, Lóbulo frontal, Terapia de reemplazamiento de hormonas, Recuerdo mental, Pruebas neuropsicológicas, Norpregnenos. Resumen: In an open study, self-ratings of bodily symptoms, mood (before and after stress), and cognitive performance were investigated in 25 women (aged 54–66 years) who for approximately 10 years had been taking an oral preparation of hormone replacement therapy (HRT), tibolone (Livial; 2.5 mg/ day). Tibolone has a unique profile, with estrogenic, progestogenic, and androgenic actions. The control group of 25 women had never taken HRT. Link: ./index.php?lvl=notice_display&id=31095 [artículo] Cognitive effects of 10 years of hormone-replacement therapy with tibolone [texto impreso] / Emma Fluck, Autor ; Sandra E. File, Autor ; Janice Rymer, Autor . - 2023 . - pp. 62-67. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2002 - Vol. 22 - No. 2 (Febrero) . - pp. 62-67 Palabras clave: Efectos climatéricos, Climatérico, Lóbulo frontal, Terapia de reemplazamiento de hormonas, Recuerdo mental, Pruebas neuropsicológicas, Norpregnenos. Resumen: In an open study, self-ratings of bodily symptoms, mood (before and after stress), and cognitive performance were investigated in 25 women (aged 54–66 years) who for approximately 10 years had been taking an oral preparation of hormone replacement therapy (HRT), tibolone (Livial; 2.5 mg/ day). Tibolone has a unique profile, with estrogenic, progestogenic, and androgenic actions. The control group of 25 women had never taken HRT. Link: ./index.php?lvl=notice_display&id=31095

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