Fluoxetine pharmacokinetics and effect on cyp2c19 in young and elderly volunteers / Anne T. Harvey en Journal of Clinical Psychopharmacology, Año 2001 - Vol. 21 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 161-166 Título : Fluoxetine pharmacokinetics and effect on cyp2c19 in young and elderly volunteers Tipo de documento: texto impreso Autores: Anne T. Harvey, Autor ; Sheldon H. Preskorn, Autor Fecha de publicación: 2023 Artículo en la página: pp. 161-166 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Citocromo P-450 CYP2C19, Sistema enzimático citocromo P-450, Fluoxetina, Oxigenasas de función mixta, Inhibidores selectivos de la recaptación de serotonina. Resumen: The objective of this study was to assess in both young and elderly volunteers the pharmacokinetics of fluoxetine and norfluoxetine and effects on cytochrome P450 (CYP) 2C19. Male volunteers aged 18 to 40 years (N = 14) or older than 65 years (N = 16) received fluoxetine 20 mg/day for 6 weeks and fluoxetine 40 mg/day for an additional 6 weeks. Link: ./index.php?lvl=notice_display&id=31120 [artículo] Fluoxetine pharmacokinetics and effect on cyp2c19 in young and elderly volunteers [texto impreso] / Anne T. Harvey, Autor ; Sheldon H. Preskorn, Autor . - 2023 . - pp. 161-166. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2001 - Vol. 21 - No. 2 (Abril) . - pp. 161-166 Palabras clave: Citocromo P-450 CYP2C19, Sistema enzimático citocromo P-450, Fluoxetina, Oxigenasas de función mixta, Inhibidores selectivos de la recaptación de serotonina. Resumen: The objective of this study was to assess in both young and elderly volunteers the pharmacokinetics of fluoxetine and norfluoxetine and effects on cytochrome P450 (CYP) 2C19. Male volunteers aged 18 to 40 years (N = 14) or older than 65 years (N = 16) received fluoxetine 20 mg/day for 6 weeks and fluoxetine 40 mg/day for an additional 6 weeks. Link: ./index.php?lvl=notice_display&id=31120

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