Therapeutic effects of imipramine are counteracted by its metabolite, desipramine, in patients with generalized anxiety disorder / Daniel R. McLeod en Journal of Clinical Psychopharmacology, Año 2000 - Vol. 20 - No. 6 (Diciembre)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 615-621 Título : Therapeutic effects of imipramine are counteracted by its metabolite, desipramine, in patients with generalized anxiety disorder Tipo de documento: texto impreso Autores: Daniel R. McLeod, Autor ; Rudolf Hoehn Saric, Autor ; Stephen W. Porges, Autor Fecha de publicación: 2023 Artículo en la página: pp. 615-621 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Inhibidores de la captación adrenérgica, Trastornos de ansiedad, Arritmias, Presión arterial, Desipramina, Frecuencia cardíaca, Imipramina. Resumen: Imipramine has been shown to reduce anxiety in patients with generalized anxiety disorder (GAD). However, some properties of imipramine may diminish or counteract its anxiolytic effects. The authors previously found that the greater the reduction in cardiac vagal control after 6 weeks of imipramine treatment, the smaller the improvement in anxiety-related symptoms. Link: ./index.php?lvl=notice_display&id=31151 [artículo] Therapeutic effects of imipramine are counteracted by its metabolite, desipramine, in patients with generalized anxiety disorder [texto impreso] / Daniel R. McLeod, Autor ; Rudolf Hoehn Saric, Autor ; Stephen W. Porges, Autor . - 2023 . - pp. 615-621. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 615-621 Palabras clave: Inhibidores de la captación adrenérgica, Trastornos de ansiedad, Arritmias, Presión arterial, Desipramina, Frecuencia cardíaca, Imipramina. Resumen: Imipramine has been shown to reduce anxiety in patients with generalized anxiety disorder (GAD). However, some properties of imipramine may diminish or counteract its anxiolytic effects. The authors previously found that the greater the reduction in cardiac vagal control after 6 weeks of imipramine treatment, the smaller the improvement in anxiety-related symptoms. Link: ./index.php?lvl=notice_display&id=31151

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