Carbamazepine-nefazodone interaction in healthy subjects / Cécile Laroudie en Journal of Clinical Psychopharmacology, Año 2000 - Vol. 20 - No. 1 (Febrero)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 1 (Febrero) . - pp. 46-53 Título : Carbamazepine-nefazodone interaction in healthy subjects Tipo de documento: texto impreso Autores: Cécile Laroudie, Autor ; Daniel E. Salazar, Autor ; Jean Philippe Cosson, Autor Fecha de publicación: 2023 Artículo en la página: pp. 46-53 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antidepresivos, Antimaníacos, Carbamazepina, Citocromo P-450 CYP2D6, Triazoles. Resumen: The pharmacokinetic interaction between nefazodone and carbamazepine was investigated in 12 healthy male volunteers. Subjects received nefazodone 200 mg twice daily for 5 days, and blood sample collection was performed on day 5 for 0- to 48-hour pharmacokinetic analysis. A 4-day washout phase then followed from days 6 to 9. Carbamazepine 200 mg was administered once daily from days 10 to 12, and then 200 mg was given twice daily from days 13 to 44. A 0- to 48-hour pharmacokinetic analysis was performed on day 38. Link: ./index.php?lvl=notice_display&id=31231 [artículo] Carbamazepine-nefazodone interaction in healthy subjects [texto impreso] / Cécile Laroudie, Autor ; Daniel E. Salazar, Autor ; Jean Philippe Cosson, Autor . - 2023 . - pp. 46-53. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 1 (Febrero) . - pp. 46-53 Palabras clave: Antidepresivos, Antimaníacos, Carbamazepina, Citocromo P-450 CYP2D6, Triazoles. Resumen: The pharmacokinetic interaction between nefazodone and carbamazepine was investigated in 12 healthy male volunteers. Subjects received nefazodone 200 mg twice daily for 5 days, and blood sample collection was performed on day 5 for 0- to 48-hour pharmacokinetic analysis. A 4-day washout phase then followed from days 6 to 9. Carbamazepine 200 mg was administered once daily from days 10 to 12, and then 200 mg was given twice daily from days 13 to 44. A 0- to 48-hour pharmacokinetic analysis was performed on day 38. Link: ./index.php?lvl=notice_display&id=31231

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