Recapitulation of perturbed striatal gene expression dynamics of donors’ brains with ventral forebrain organoids derived from the same individuals with schizophrenia / Tomoyo Sawada en The American Journal of Psychiatry, Año 2024 - Vol. 181 - No. 6 (Junio)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2024 - Vol. 181 - No. 6 (Junio) . - pp. 493-511 Título : Recapitulation of perturbed striatal gene expression dynamics of donors’ brains with ventral forebrain organoids derived from the same individuals with schizophrenia Tipo de documento: texto impreso Autores: Tomoyo Sawada, Autor ; André R. Barbosa, Autor ; Bruno Araujo, Autor Fecha de publicación: 2024 Artículo en la página: pp. 493-511 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Genética - Genómica, Espectro de la esquizofrenia y otros trastornos psicóticos. Resumen: Schizophrenia is a brain disorder that originates during neurodevelopment and has complex genetic and environmental etiologies. Despite decades of clinical evidence of altered striatal function in affected patients, studies examining its cellular and molecular mechanisms in humans are limited. Link: ./index.php?lvl=notice_display&id=31405 [artículo] Recapitulation of perturbed striatal gene expression dynamics of donors’ brains with ventral forebrain organoids derived from the same individuals with schizophrenia [texto impreso] / Tomoyo Sawada, Autor ; André R. Barbosa, Autor ; Bruno Araujo, Autor . - 2024 . - pp. 493-511. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2024 - Vol. 181 - No. 6 (Junio) . - pp. 493-511 Palabras clave: Genética - Genómica, Espectro de la esquizofrenia y otros trastornos psicóticos. Resumen: Schizophrenia is a brain disorder that originates during neurodevelopment and has complex genetic and environmental etiologies. Despite decades of clinical evidence of altered striatal function in affected patients, studies examining its cellular and molecular mechanisms in humans are limited. Link: ./index.php?lvl=notice_display&id=31405

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