Genome-wide association study of treatment-resistant depression: shared biology with metabolic traits / JooEun Kang en The American Journal of Psychiatry, Año 2024 - Vol. 181 - No. 7 (Julio)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2024 - Vol. 181 - No. 7 (Julio) . - pp. 608-619 Título : Genome-wide association study of treatment-resistant depression: shared biology with metabolic traits Tipo de documento: texto impreso Autores: JooEun Kang, Autor ; Victor M. Castro, Autor ; Michael Ripperger, Autor Fecha de publicación: 2025 Artículo en la página: pp. 608-619 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastornos depresivos, Terapia electroconvulsiva (TEC), Genética - Genómica, Trastorno depresivo mayor, Depresión resistente al tratamiento. Resumen: Treatment-resistant depression (TRD) occurs in roughly one-third of all individuals with major depressive disorder (MDD). Although research has suggested a significant common variant genetic component of liability to TRD, with heritability estimated at 8% when compared with non-treatment-resistant MDD, no replicated genetic loci have been identified, and the genetic architecture of TRD remains unclear. Link: ./index.php?lvl=notice_display&id=31512 [artículo] Genome-wide association study of treatment-resistant depression: shared biology with metabolic traits [texto impreso] / JooEun Kang, Autor ; Victor M. Castro, Autor ; Michael Ripperger, Autor . - 2025 . - pp. 608-619. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2024 - Vol. 181 - No. 7 (Julio) . - pp. 608-619 Palabras clave: Trastornos depresivos, Terapia electroconvulsiva (TEC), Genética - Genómica, Trastorno depresivo mayor, Depresión resistente al tratamiento. Resumen: Treatment-resistant depression (TRD) occurs in roughly one-third of all individuals with major depressive disorder (MDD). Although research has suggested a significant common variant genetic component of liability to TRD, with heritability estimated at 8% when compared with non-treatment-resistant MDD, no replicated genetic loci have been identified, and the genetic architecture of TRD remains unclear. Link: ./index.php?lvl=notice_display&id=31512

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