[artículo] 
inThe American Journal of Psychiatry > Año 2020 - Vol. 177 - No.12 (Diciembre) . - pp. 1129-1139

Título :	Association of missense mutation in FOLH1 with decreased NAAG levels and impaired working memory circuitry and cognition
Tipo de documento:	texto impreso
Autores:	Caroline F. Zink, Autor ; Peter B. Barker, Autor ; Akira Sawa, Autor
Fecha de publicación:	2021
Artículo en la página:	pp. 1129-1139
Idioma :	Inglés (eng) Idioma original : Inglés (eng)
Palabras clave:	Genética, Cognición, Mutaciones, N-acetil-aspartil-glutamato
Resumen:	Altering the metabotropic glutamate receptor 3 (mGluR3) by pharmacology or genetics is associated with differences in learning and memory in animals and humans. GRM3 (the gene coding for mGluR3) is also genome-wide associated with risk for schizophrenia. The neurotransmitter N-acetyl-aspartyl-glutamate (NAAG) is the selective endogenous agonist of mGluR3, and increasing NAAG may improve cognition.
Link:	./index.php?lvl=notice_display&id=25789

[artículo] Association of missense mutation in FOLH1 with decreased NAAG levels and impaired working memory circuitry and cognition [texto impreso] / Caroline F. Zink, Autor ; Peter B. Barker, Autor ; Akira Sawa, Autor . - 2021 . - pp. 1129-1139.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in The American Journal of Psychiatry > Año 2020 - Vol. 177 - No.12 (Diciembre) . - pp. 1129-1139

Palabras clave:	Genética, Cognición, Mutaciones, N-acetil-aspartil-glutamato
Resumen:	Altering the metabotropic glutamate receptor 3 (mGluR3) by pharmacology or genetics is associated with differences in learning and memory in animals and humans. GRM3 (the gene coding for mGluR3) is also genome-wide associated with risk for schizophrenia. The neurotransmitter N-acetyl-aspartyl-glutamate (NAAG) is the selective endogenous agonist of mGluR3, and increasing NAAG may improve cognition.
Link:	./index.php?lvl=notice_display&id=25789