Biblioteca Humberto Rosselli Quijano
[artículo]
| Título : |
Alterations in brain-derived neurotrophic factor (BDNF) and its precursor proBDNF in the brain regions of a learned helplessness rat model and the antidepressant effects of a TrkB agonist and antagonist |
| Tipo de documento: |
texto impreso |
| Autores: |
Yukihikko Shirayama, Autor ; Chun Yang, Autor ; Jichun Zhang, Autor |
| Fecha de publicación: |
2021 |
| Artículo en la página: |
pp. 2449-2458 |
| Idioma : |
Inglés (eng) Idioma original : Inglés (eng) |
| Palabras clave: |
Factor neurotrófico derivado del cerebro, Hipocampo, Corteza infralímbica, Núcleo accumbens, Corteza preliminar, proBDNF |
| Resumen: |
Role of brain-derived neurotrophic factor (BDNF)-TrkB signaling in a learned helplessness (LH) model of depression was investigated. LH rats showed a reduction of BDNF in the medial prefrontal cortex (mPFC), CA3, and dentate gyrus (DG) of the hippocampus, whereas LH rats showed an increase in BDNF in the nucleus accumbens (NAc). Furthermore,... |
| Link: |
./index.php?lvl=notice_display&id=26671 |
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.12 (Diciembre) . - pp. 2449-2458
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