[artículo] 
inEuropean Neuropsychopharmacology > Año 2015 - Vol. 25 - No.11 (Noviembre) . - pp. 2170-2182

Título :	Leucettine L41, a DYRK1A-preferential DYRKs/CLKs inhibitor, prevents memory impairments and neurotoxicity induced by oligomeric Aβ25–35 peptide administration in mice
Tipo de documento:	texto impreso
Autores:	Gaëlle Naert, Autor ; Valentine Ferré, Autor ; Johann Meunier, Autor
Fecha de publicación:	2021
Artículo en la página:	pp. 2170-2182
Idioma :	Inglés (eng) Idioma original : Inglés (eng)
Palabras clave:	Quinasa, DYRK1A, Leucettines, Aβ  25–35, Toxicidad amiloide, Fosforilación de tau
Resumen:	Dual-specificity tyrosine phosphorylation-regulated kinases (DYRKs) and cdc2-like kinases (CLKs) are implicated in the onset and progression of Down syndrome (DS) and Alzheimer’s disease (AD). DYRK1A has emerged as a possible link between amyloid-β (Aβ) and Tau, the major pathological proteins in AD.
Link:	./index.php?lvl=notice_display&id=26703

[artículo] Leucettine L41, a DYRK1A-preferential DYRKs/CLKs inhibitor, prevents memory impairments and neurotoxicity induced by oligomeric Aβ25–35 peptide administration in mice [texto impreso] / Gaëlle Naert, Autor ; Valentine Ferré, Autor ; Johann Meunier, Autor . - 2021 . - pp. 2170-2182.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.11 (Noviembre) . - pp. 2170-2182

Palabras clave:	Quinasa, DYRK1A, Leucettines, Aβ  25–35, Toxicidad amiloide, Fosforilación de tau
Resumen:	Dual-specificity tyrosine phosphorylation-regulated kinases (DYRKs) and cdc2-like kinases (CLKs) are implicated in the onset and progression of Down syndrome (DS) and Alzheimer’s disease (AD). DYRK1A has emerged as a possible link between amyloid-β (Aβ) and Tau, the major pathological proteins in AD.
Link:	./index.php?lvl=notice_display&id=26703