[artículo] 
inEuropean Neuropsychopharmacology > Año 2015 - Vol. 25 - No.9 (Septiembre) . - pp. 1448-1461

Título :	Investigation of the binding and functional properties of extended length D3 dopamine receptor-selective antagonists
Tipo de documento:	texto impreso
Autores:	Cheryse A. Furman, Autor ; Rebecca A. Roof, Autor ; Amy E. Moritz, Autor
Fecha de publicación:	2021
Artículo en la página:	pp. 1448-1461
Idioma :	Inglés (eng) Idioma original : Inglés (eng)
Palabras clave:	Receptor de dopamina, Receptor D3, Bivalente, Bitopic, Alostérico, Antagonistas de la dopamina
Resumen:	The D3 dopamine receptor represents an important target in drug addiction in that reducing receptor activity may attenuate the self-administration of drugs and/or disrupt drug or cue-induced relapse. Medicinal chemistry efforts have led to the development of D3 preferring antagonists and partial agonists that are >100-fold selective vs.
Link:	./index.php?lvl=notice_display&id=26742

[artículo] Investigation of the binding and functional properties of extended length D3 dopamine receptor-selective antagonists [texto impreso] / Cheryse A. Furman, Autor ; Rebecca A. Roof, Autor ; Amy E. Moritz, Autor . - 2021 . - pp. 1448-1461.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.9 (Septiembre) . - pp. 1448-1461

Palabras clave:	Receptor de dopamina, Receptor D3, Bivalente, Bitopic, Alostérico, Antagonistas de la dopamina
Resumen:	The D3 dopamine receptor represents an important target in drug addiction in that reducing receptor activity may attenuate the self-administration of drugs and/or disrupt drug or cue-induced relapse. Medicinal chemistry efforts have led to the development of D3 preferring antagonists and partial agonists that are >100-fold selective vs.
Link:	./index.php?lvl=notice_display&id=26742