[artículo] 
inThe American Journal of Psychiatry > Año 2021 - Vol. 178 - No.9 (Septiembre) . - pp. 829-837

Título :	Effects of gabapentin on dorsal anterior cingulate cortex gaba and glutamate levels and their associations with abstinence in alcohol use disorder : a randomized clinical trial
Tipo de documento:	texto impreso
Autores:	James J. Prisciandaro, Autor ; Michaela Hoffman, Autor ; Truman R. Brown, Autor
Fecha de publicación:	2021
Artículo en la página:	pp. 829-837
Idioma :	Inglés (eng) Idioma original : Inglés (eng)
Palabras clave:	Neuroimagen, Trastornos adictivos y relacionados con sustancias, Alcohol, Anticonvulsivos
Resumen:	Although gabapentin has demonstrated efficacy in mitigating alcohol withdrawal symptoms and preventing relapse drinking in individuals with alcohol use disorder (AUD), the neurobiological mechanisms of action underlying these therapeutic effects remain unknown. The present study evaluated changes in GABA and glutamate levels in the dorsal anterior cingulate cortex (dACC) as candidate mechanisms of action.
Link:	./index.php?lvl=notice_display&id=27334

[artículo] Effects of gabapentin on dorsal anterior cingulate cortex gaba and glutamate levels and their associations with abstinence in alcohol use disorder : a randomized clinical trial [texto impreso] / James J. Prisciandaro, Autor ; Michaela Hoffman, Autor ; Truman R. Brown, Autor . - 2021 . - pp. 829-837.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in The American Journal of Psychiatry > Año 2021 - Vol. 178 - No.9 (Septiembre) . - pp. 829-837

Palabras clave:	Neuroimagen, Trastornos adictivos y relacionados con sustancias, Alcohol, Anticonvulsivos
Resumen:	Although gabapentin has demonstrated efficacy in mitigating alcohol withdrawal symptoms and preventing relapse drinking in individuals with alcohol use disorder (AUD), the neurobiological mechanisms of action underlying these therapeutic effects remain unknown. The present study evaluated changes in GABA and glutamate levels in the dorsal anterior cingulate cortex (dACC) as candidate mechanisms of action.
Link:	./index.php?lvl=notice_display&id=27334