[artículo] 
inThe Journal of Clinical Psychiatry > Año 2011 - Vol.72 - No. 4 (Abril) . - pp. 458-463

Título :	Candidate gene analysis identifies a polymorphism in HLA-DQB1 associated with clozapine induced agranulocytosis
Tipo de documento:	texto impreso
Autores:	Maria C. Athanasiou, Autor ; Michael Dettling, Autor ; Ingolf Cascorbi, Autor
Fecha de publicación:	2022
Artículo en la página:	pp. 458-463
Idioma :	Inglés (eng) Idioma original : Inglés (eng)
Palabras clave:	Agranulocitosis, Antipsicóticos, Clozapina, Predisposición genética a la enfermedad, Antígenos HLA-DQ, Polimorfismo.
Resumen:	Clozapine is considered to be the most efficacious drug to treat schizophrenia, although it is underutilized, partially due to a side effect of agranulocytosis. This analysis of 74 candidate genes was designed to identify an association between sequence variants and clozapine-induced agranulocytosis (CIA).
Link:	./index.php?lvl=notice_display&id=27970

[artículo] Candidate gene analysis identifies a polymorphism in HLA-DQB1 associated with clozapine induced agranulocytosis [texto impreso] / Maria C. Athanasiou, Autor ; Michael Dettling, Autor ; Ingolf Cascorbi, Autor . - 2022 . - pp. 458-463.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in The Journal of Clinical Psychiatry > Año 2011 - Vol.72 - No. 4 (Abril) . - pp. 458-463

Palabras clave:	Agranulocitosis, Antipsicóticos, Clozapina, Predisposición genética a la enfermedad, Antígenos HLA-DQ, Polimorfismo.
Resumen:	Clozapine is considered to be the most efficacious drug to treat schizophrenia, although it is underutilized, partially due to a side effect of agranulocytosis. This analysis of 74 candidate genes was designed to identify an association between sequence variants and clozapine-induced agranulocytosis (CIA).
Link:	./index.php?lvl=notice_display&id=27970