[artículo]
Título : |
Effects of CYP2D6 genotype on the pharmacokinetics, pharmacodynamics, and safety of risperidone in healthy volunteers |
Tipo de documento: |
texto impreso |
Autores: |
Jesús Novalbos, Autor ; Rosario López Rodríguez, Autor ; Manuel Román, Autor |
Fecha de publicación: |
2022 |
Artículo en la página: |
pp. 504-511 |
Idioma : |
Inglés (eng) Idioma original : Inglés (eng) |
Palabras clave: |
CYP2D6, Risperidona, 9-hidroxirisperidona, Farmacogenética, Farmacocinética, Voluntarios sanos |
Resumen: |
The objective of this study was to analyze the relationship between CYP2D6 genotype and pharmacokinetics and pharmacodynamics of risperidone. Seventy-one healthy volunteers (36 women and 35 men) received a 1-mg single oral dose of risperidone. Six major CYP2D6 polymorphisms (CYP2D6*3, *4, *5, *6, *7, and *9) and the duplication were detected. |
Link: |
./index.php?lvl=notice_display&id=29422 |
in Journal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 5 (Octubre) . - pp. 504-511
[artículo] Effects of CYP2D6 genotype on the pharmacokinetics, pharmacodynamics, and safety of risperidone in healthy volunteers [texto impreso] / Jesús Novalbos, Autor ; Rosario López Rodríguez, Autor ; Manuel Román, Autor . - 2022 . - pp. 504-511. Idioma : Inglés ( eng) Idioma original : Inglés ( eng) in Journal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 5 (Octubre) . - pp. 504-511
Palabras clave: |
CYP2D6, Risperidona, 9-hidroxirisperidona, Farmacogenética, Farmacocinética, Voluntarios sanos |
Resumen: |
The objective of this study was to analyze the relationship between CYP2D6 genotype and pharmacokinetics and pharmacodynamics of risperidone. Seventy-one healthy volunteers (36 women and 35 men) received a 1-mg single oral dose of risperidone. Six major CYP2D6 polymorphisms (CYP2D6*3, *4, *5, *6, *7, and *9) and the duplication were detected. |
Link: |
./index.php?lvl=notice_display&id=29422 |
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