[artículo]
| Título : |
Olanzapine plasma concentrations after treatment with 10, 20, and 40 mg/d in patients with schizophrenia : An analysis of correlations with efficacy, weight gain, and prolactin concentration |
| Tipo de documento: |
texto impreso |
| Autores: |
Leslie L. Citrome, Autor ; Virginia L. Stauffer, Autor ; Lei Chen, Autor |
| Fecha de publicación: |
2022 |
| Artículo en la página: |
pp. 278-283 |
| Idioma : |
Inglés (eng) Idioma original : Inglés (eng) |
| Palabras clave: |
Olanzapina, Farmacocinética, Prolactina, Esquizofrenia, Tabaquismo. |
| Resumen: |
Objectives of the study were to evaluate the relationship between olanzapine plasma concentrations and efficacy, prolactin, and weight and to assess effects of smoking, sex, and race on the pharmacokinetic characteristics of oral olanzapine up to 40 mg/d. Patients were randomly allocated to olanzapine 10, 20, or 40 mg/d for 8 weeks. Olanzapine concentrations in 634 samples from 380 patients were analyzed. |
| Link: |
./index.php?lvl=notice_display&id=29510 |
in Journal of Clinical Psychopharmacology > Año 2009 - Vol. 29 - No. 3 (Junio) . - pp. 278-283
[artículo] Olanzapine plasma concentrations after treatment with 10, 20, and 40 mg/d in patients with schizophrenia : An analysis of correlations with efficacy, weight gain, and prolactin concentration [texto impreso] / Leslie L. Citrome, Autor ; Virginia L. Stauffer, Autor ; Lei Chen, Autor . - 2022 . - pp. 278-283. Idioma : Inglés ( eng) Idioma original : Inglés ( eng) in Journal of Clinical Psychopharmacology > Año 2009 - Vol. 29 - No. 3 (Junio) . - pp. 278-283
| Palabras clave: |
Olanzapina, Farmacocinética, Prolactina, Esquizofrenia, Tabaquismo. |
| Resumen: |
Objectives of the study were to evaluate the relationship between olanzapine plasma concentrations and efficacy, prolactin, and weight and to assess effects of smoking, sex, and race on the pharmacokinetic characteristics of oral olanzapine up to 40 mg/d. Patients were randomly allocated to olanzapine 10, 20, or 40 mg/d for 8 weeks. Olanzapine concentrations in 634 samples from 380 patients were analyzed. |
| Link: |
./index.php?lvl=notice_display&id=29510 |
|
Olanzapine plasma concentrations after treatment with 10, 20, and 40 mg/d in patients with schizophrenia en Journal of Clinical Psychopharmacology, Año 2009 - Vol. 29 - No. 3 (Junio)
