[artículo] 
inJournal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 608-617

Título :	Striatal and extrastriatal d2/d3-receptor-binding properties of ziprasidone : A positron emission tomography study with [18F]fallypride and [11C]raclopride (D2/D3-receptor occupancy of ziprasidone)
Tipo de documento:	texto impreso
Autores:	Ingo B. Vernaleken, Autor ; Christine Fellows, Autor ; Hildegard Janouschek, Autor
Fecha de publicación:	2023
Artículo en la página:	pp. 608-617
Idioma :	Inglés (eng) Idioma original : Inglés (eng)
Palabras clave:	Agentes antipsicóticos, Relación Dosis-Respuesta, Piperazinas, Radiofármacos, Receptores de Dopamina D2, Esquizofrenia.
Resumen:	To elucidate the "atypicality" of ziprasidone, its striatal and extrastriatal D2/D3-receptor binding was characterized in patients with schizophrenia under steady-state conditions. These data were compared with striatal receptor occupancy values after single-dose ziprasidone ingestion in healthy controls. [18F]fallypride positron emission tomography (PET) recordings were obtained in 15 patients under steady-state ziprasidone treatment at varying time points after the last dose.
Link:	./index.php?lvl=notice_display&id=30818

[artículo] Striatal and extrastriatal d2/d3-receptor-binding properties of ziprasidone : A positron emission tomography study with [18F]fallypride and [11C]raclopride (D2/D3-receptor occupancy of ziprasidone) [texto impreso] / Ingo B. Vernaleken, Autor ; Christine Fellows, Autor ; Hildegard Janouschek, Autor . - 2023 . - pp. 608-617.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2008 - Vol. 28 - No. 6 (Diciembre) . - pp. 608-617

Palabras clave:	Agentes antipsicóticos, Relación Dosis-Respuesta, Piperazinas, Radiofármacos, Receptores de Dopamina D2, Esquizofrenia.
Resumen:	To elucidate the "atypicality" of ziprasidone, its striatal and extrastriatal D2/D3-receptor binding was characterized in patients with schizophrenia under steady-state conditions. These data were compared with striatal receptor occupancy values after single-dose ziprasidone ingestion in healthy controls. [18F]fallypride positron emission tomography (PET) recordings were obtained in 15 patients under steady-state ziprasidone treatment at varying time points after the last dose.
Link:	./index.php?lvl=notice_display&id=30818