[artículo]
| Título : |
Clozapine induces oxidative stress and proapoptotic gene expression in neutrophils of schizophrenic patients |
| Tipo de documento: |
texto impreso |
| Autores: |
Karin Fehsel, Autor ; Stefan Loeffler, Autor ; Klaus Krieger, Autor |
| Fecha de publicación: |
2023 |
| Artículo en la página: |
pp. 419-426 |
| Idioma : |
Inglés (eng) Idioma original : Inglés (eng) |
| Palabras clave: |
Antipsicóticos, Apoptosis, Clozapina, Expresión genética, Genes, Técnicas In Vitro, Leucocitos, Neutrófilos, Estrés oxidativo, Esquizofrenia. |
| Resumen: |
The present study examined cellular effects of the atypical antipsychotic drug clozapine on blood cells of treated patients with and without clozapine-induced agranulocytosis (CA). Blood from one patient who commenced clozapine treatment was examined at weekly intervals for 128 days. Olanzapine-treated (n = 5) and polymedicated (n = 14) schizophrenic patients, as well as healthy subjects (n = 19) and septic shock patients (n = 8), were studied for comparison. |
| Link: |
./index.php?lvl=notice_display&id=30886 |
in Journal of Clinical Psychopharmacology > Año 2005 - Vol. 25 - No. 5 (Octubre) . - pp. 419-426
[artículo] Clozapine induces oxidative stress and proapoptotic gene expression in neutrophils of schizophrenic patients [texto impreso] / Karin Fehsel, Autor ; Stefan Loeffler, Autor ; Klaus Krieger, Autor . - 2023 . - pp. 419-426. Idioma : Inglés ( eng) Idioma original : Inglés ( eng) in Journal of Clinical Psychopharmacology > Año 2005 - Vol. 25 - No. 5 (Octubre) . - pp. 419-426
| Palabras clave: |
Antipsicóticos, Apoptosis, Clozapina, Expresión genética, Genes, Técnicas In Vitro, Leucocitos, Neutrófilos, Estrés oxidativo, Esquizofrenia. |
| Resumen: |
The present study examined cellular effects of the atypical antipsychotic drug clozapine on blood cells of treated patients with and without clozapine-induced agranulocytosis (CA). Blood from one patient who commenced clozapine treatment was examined at weekly intervals for 128 days. Olanzapine-treated (n = 5) and polymedicated (n = 14) schizophrenic patients, as well as healthy subjects (n = 19) and septic shock patients (n = 8), were studied for comparison. |
| Link: |
./index.php?lvl=notice_display&id=30886 |
|
Clozapine induces oxidative stress and proapoptotic gene expression in neutrophils of schizophrenic patients en Journal of Clinical Psychopharmacology, Año 2005 - Vol. 25 - No. 5 (Octubre)
