[artículo] 
inJournal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 6 (Diciembre) . - pp. 613-617

Título :	Impact of myeloperoxidase and nadph-oxidase polymorphisms in drug-induced agranulocytosis
Tipo de documento:	texto impreso
Autores:	Igor Mosyagin, Autor ; Michael Dettling, Autor ; Ivar Roots, Autor
Fecha de publicación:	2023
Artículo en la página:	pp. 613-617
Idioma :	Inglés (eng) Idioma original : Inglés (eng)
Palabras clave:	Agranulocitosis, Agentes antipsicóticos, Peroxidasa, Esquizofrenia.
Resumen:	Therapy of the atypical antipsychotic drug clozapine is limited by a comparatively high incidence of agranulocytosis in 0.8% of patients. This severe side effect is possibly based on the clozapine-mediated stimulation of cytokines and soluble cytokine receptors release, followed by induction of granulocyte proliferation and induction of myeloperoxidase (MPO) and NADPH-oxidase.
Link:	./index.php?lvl=notice_display&id=30933

[artículo] Impact of myeloperoxidase and nadph-oxidase polymorphisms in drug-induced agranulocytosis [texto impreso] / Igor Mosyagin, Autor ; Michael Dettling, Autor ; Ivar Roots, Autor . - 2023 . - pp. 613-617.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2004 - Vol. 24 - No. 6 (Diciembre) . - pp. 613-617

Palabras clave:	Agranulocitosis, Agentes antipsicóticos, Peroxidasa, Esquizofrenia.
Resumen:	Therapy of the atypical antipsychotic drug clozapine is limited by a comparatively high incidence of agranulocytosis in 0.8% of patients. This severe side effect is possibly based on the clozapine-mediated stimulation of cytokines and soluble cytokine receptors release, followed by induction of granulocyte proliferation and induction of myeloperoxidase (MPO) and NADPH-oxidase.
Link:	./index.php?lvl=notice_display&id=30933