[artículo] 
inJournal of Clinical Psychopharmacology > Año 2002 - Vol. 22 - No. 4 (Agosto) . - pp. 414-418

Título :	A typological model for estimation of drug and placebo effects in depression
Tipo de documento:	texto impreso
Autores:	Donald C. Ross, Autor ; Frederic Quitkin, Autor ; Donald F. Klein, Autor
Fecha de publicación:	2023
Artículo en la página:	pp. 414-418
Idioma :	Inglés (eng) Idioma original : Inglés (eng)
Palabras clave:	Antidepresivos, Ensayos clínicos, Trastorno depresivo mayor, Fluoxetina, Imipramina.
Resumen:	One reason for failure to find specific treatment effects in drug versus placebo trials with patients who have depression is an insufficient period of observation. Also, differentiating between early fleeting response and maintained response has been shown relevant to detecting specific drug action. A model in which various types of drug and placebo response are specifically stipulated and which takes advantage of a two-stage experimental design is proposed.
Link:	./index.php?lvl=notice_display&id=31059

[artículo] A typological model for estimation of drug and placebo effects in depression [texto impreso] / Donald C. Ross, Autor ; Frederic Quitkin, Autor ; Donald F. Klein, Autor . - 2023 . - pp. 414-418.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2002 - Vol. 22 - No. 4 (Agosto) . - pp. 414-418

Palabras clave:	Antidepresivos, Ensayos clínicos, Trastorno depresivo mayor, Fluoxetina, Imipramina.
Resumen:	One reason for failure to find specific treatment effects in drug versus placebo trials with patients who have depression is an insufficient period of observation. Also, differentiating between early fleeting response and maintained response has been shown relevant to detecting specific drug action. A model in which various types of drug and placebo response are specifically stipulated and which takes advantage of a two-stage experimental design is proposed.
Link:	./index.php?lvl=notice_display&id=31059