[artículo] 
inJournal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 685-690

Título :	Epidemiologic investigation of the relative clearance of haloperidol by mixed-effect modeling using routine clinical pharmacokinetic data in japanese patients
Tipo de documento:	texto impreso
Autores:	Eiji Yukawa, Autor ; Tsuyoshi Hokazono, Autor ; Akiko Funakoshi, Autor
Fecha de publicación:	2023
Artículo en la página:	pp. 685-690
Idioma :	Inglés (eng) Idioma original : Inglés (eng)
Palabras clave:	Antipsicóticos, Haloperidol, Japón, Modelos biológicos, Esquizofrenia.
Resumen:	The steady-state trough concentrations of haloperidol were studied to clarify the role of the characteristics of Japanese patients in estimating haloperidol dosing regimens by using routine therapeutic drug-monitoring data. Nonlinear mixed-effects modeling (NONMEM) was used to estimate the effect of a variety of developmental and demographic factors on haloperidol clearance values using 270 serum level measurements obtained from 191 patients during their clinical course.
Link:	./index.php?lvl=notice_display&id=31161

[artículo] Epidemiologic investigation of the relative clearance of haloperidol by mixed-effect modeling using routine clinical pharmacokinetic data in japanese patients [texto impreso] / Eiji Yukawa, Autor ; Tsuyoshi Hokazono, Autor ; Akiko Funakoshi, Autor . - 2023 . - pp. 685-690.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 685-690

Palabras clave:	Antipsicóticos, Haloperidol, Japón, Modelos biológicos, Esquizofrenia.
Resumen:	The steady-state trough concentrations of haloperidol were studied to clarify the role of the characteristics of Japanese patients in estimating haloperidol dosing regimens by using routine therapeutic drug-monitoring data. Nonlinear mixed-effects modeling (NONMEM) was used to estimate the effect of a variety of developmental and demographic factors on haloperidol clearance values using 270 serum level measurements obtained from 191 patients during their clinical course.
Link:	./index.php?lvl=notice_display&id=31161