Artículos

Pharmacogenomics of psychiatric drug treatment / David Pickar en Psychiatric Clinics of North America, Año 2003 - Vol. 26 No. 2 (Junio)

Público ISBD [artículo]  inPsychiatric Clinics of North America > Año 2003 - Vol. 26 No. 2 (Junio) . - pp. 303-321 Título : Pharmacogenomics of psychiatric drug treatment Tipo de documento: texto impreso Autores: David Pickar, Autor Fecha de publicación: 2020 Artículo en la página: pp. 303-321 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Relación dosis-respuesta, Trastornos mentales -farmacoterapia, Trastornos mentales, Farmacogenética, Fármacos psicotrópicos, Drogas psicotrópicas. Resumen: It is the goal of pharmacogenomics in psychiatry to establish predictive relationships between polymorphisms of candidate genes and therapeutic response to drug treatment. Polymorphisms of candidate genes related to drug mechanisms and pathophysiology of illness and defined clinical phenotype are the foundations for pharmacogenomic studies. Link: ./index.php?lvl=notice_display&id=24809 [artículo] Pharmacogenomics of psychiatric drug treatment [texto impreso] / David Pickar, Autor . - 2020 . - pp. 303-321. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Psychiatric Clinics of North America > Año 2003 - Vol. 26 No. 2 (Junio) . - pp. 303-321 Palabras clave: Relación dosis-respuesta, Trastornos mentales -farmacoterapia, Trastornos mentales, Farmacogenética, Fármacos psicotrópicos, Drogas psicotrópicas. Resumen: It is the goal of pharmacogenomics in psychiatry to establish predictive relationships between polymorphisms of candidate genes and therapeutic response to drug treatment. Polymorphisms of candidate genes related to drug mechanisms and pathophysiology of illness and defined clinical phenotype are the foundations for pharmacogenomic studies. Link: ./index.php?lvl=notice_display&id=24809

Biological predictors of treatment response in affective illness / Roy H. Perlis en Psychiatric Clinics of North America, Año 2003 - Vol. 26 No. 2 (Junio)

Público ISBD [artículo]  inPsychiatric Clinics of North America > Año 2003 - Vol. 26 No. 2 (Junio) . - pp. 323-344 Título : Biological predictors of treatment response in affective illness Tipo de documento: texto impreso Autores: Roy H. Perlis, Autor ; Dan V. Iosifescu, Autor ; Perry F. Renshaw, Autor Fecha de publicación: 2020 Artículo en la página: pp. 323-344 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Fisiopatología - cerebro, Electroencefalografía, Potenciales evocados, Trastornos del estado de ánimo, Sistemas neurosecretores, Tomografía computarizada por rayos X. Resumen: Attempts to identify biological response predictors generally have met with limited success, particularly where the goal is to develop clinically useful indices. This article reviews the biological approaches to predicting treatment response, beginning with neuroendocrine studies and electroencephalogram analysis and concluding with structural and functional neuroimaging. Link: ./index.php?lvl=notice_display&id=24810 [artículo] Biological predictors of treatment response in affective illness [texto impreso] / Roy H. Perlis, Autor ; Dan V. Iosifescu, Autor ; Perry F. Renshaw, Autor . - 2020 . - pp. 323-344. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Psychiatric Clinics of North America > Año 2003 - Vol. 26 No. 2 (Junio) . - pp. 323-344 Palabras clave: Fisiopatología - cerebro, Electroencefalografía, Potenciales evocados, Trastornos del estado de ánimo, Sistemas neurosecretores, Tomografía computarizada por rayos X. Resumen: Attempts to identify biological response predictors generally have met with limited success, particularly where the goal is to develop clinically useful indices. This article reviews the biological approaches to predicting treatment response, beginning with neuroendocrine studies and electroencephalogram analysis and concluding with structural and functional neuroimaging. Link: ./index.php?lvl=notice_display&id=24810

Predictors of response to antidepressants / Andrew A. Nierenberg en Psychiatric Clinics of North America, Año 2003 - Vol. 26 No. 2 (Junio)

Público ISBD [artículo]  inPsychiatric Clinics of North America > Año 2003 - Vol. 26 No. 2 (Junio) . - pp. 345-352 Título : Predictors of response to antidepressants : General principles and clinical implications Tipo de documento: texto impreso Autores: Andrew A. Nierenberg, Autor Fecha de publicación: 2020 Artículo en la página: pp. 345-352 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Agentes antidepresivos, Trastorno depresivo, Pronóstico. Resumen: What variables will predict who should be treated with antidepressants and who should not? If someone should be treated, what variables will predict which treatment is most likely to work? If patients are treated, what will predict who will respond and who will not? Clinicians have asked these questions ever since researchers established that antidepressants were superior to placebo in the treatment of depression. Link: ./index.php?lvl=notice_display&id=24811 [artículo] Predictors of response to antidepressants : General principles and clinical implications [texto impreso] / Andrew A. Nierenberg, Autor . - 2020 . - pp. 345-352. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Psychiatric Clinics of North America > Año 2003 - Vol. 26 No. 2 (Junio) . - pp. 345-352 Palabras clave: Agentes antidepresivos, Trastorno depresivo, Pronóstico. Resumen: What variables will predict who should be treated with antidepressants and who should not? If someone should be treated, what variables will predict which treatment is most likely to work? If patients are treated, what will predict who will respond and who will not? Clinicians have asked these questions ever since researchers established that antidepressants were superior to placebo in the treatment of depression. Link: ./index.php?lvl=notice_display&id=24811

Treatment of schizophrenia en Psychiatric Clinics of North America, Año 2003 - Vol. 26 No. 2 (Junio)

Público ISBD [artículo]  inPsychiatric Clinics of North America > Año 2003 - Vol. 26 No. 2 (Junio) . - pp. 367-379 Título : Treatment of schizophrenia : preventing the progression of disease Tipo de documento: texto impreso Fecha de publicación: 2020 Artículo en la página: pp. 367-379 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Enfermedad aguda, Agentes antipsicóticos, Análisis costo-beneficio, Enfermedad progresiva, Esquizofrenia. Resumen: Atypical antipsychotic drugs offer a number of advantages compared with typical antipsychotic drugs during the acute treatment of psychotic episodes and maintenance treatment to prevent psychotic relapses in patients with schizophrenia. Link: ./index.php?lvl=notice_display&id=24812 [artículo] Treatment of schizophrenia : preventing the progression of disease [texto impreso] . - 2020 . - pp. 367-379. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Psychiatric Clinics of North America > Año 2003 - Vol. 26 No. 2 (Junio) . - pp. 367-379 Palabras clave: Enfermedad aguda, Agentes antipsicóticos, Análisis costo-beneficio, Enfermedad progresiva, Esquizofrenia. Resumen: Atypical antipsychotic drugs offer a number of advantages compared with typical antipsychotic drugs during the acute treatment of psychotic episodes and maintenance treatment to prevent psychotic relapses in patients with schizophrenia. Link: ./index.php?lvl=notice_display&id=24812

Outcome predictors in substance use disorders / Domenic A. Ciraulo en Psychiatric Clinics of North America, Año 2003 - Vol. 26 No. 2 (Junio)

Público ISBD [artículo]  inPsychiatric Clinics of North America > Año 2003 - Vol. 26 No. 2 (Junio) . - pp. 381-409 Título : Outcome predictors in substance use disorders Tipo de documento: texto impreso Autores: Domenic A. Ciraulo, Autor ; Joanna Piechniczek-Buczek,, Autor ; E. Nalan Iscan, Autor Fecha de publicación: 2020 Artículo en la página: pp. 381-409 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Biomarcadores, Cerebro, Cognición, Electroencefalografía, Agentes neurotransmisores, Personalidad, Pronóstico, Índice de gravedad de la enfermedad, Trastornos relacionados con sustancias, Tratamiento. Resumen: Given the heterogeneous nature of substance abuse, it is notable that several predictors of response are independent of the primary drug of abuse or the treatment setting [208]. Although the strength of the relationship of predictor to outcome varies, the following factors have been identified consistently: severity of dependence or withdrawal;... Link: ./index.php?lvl=notice_display&id=24813 [artículo] Outcome predictors in substance use disorders [texto impreso] / Domenic A. Ciraulo, Autor ; Joanna Piechniczek-Buczek,, Autor ; E. Nalan Iscan, Autor . - 2020 . - pp. 381-409. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Psychiatric Clinics of North America > Año 2003 - Vol. 26 No. 2 (Junio) . - pp. 381-409 Palabras clave: Biomarcadores, Cerebro, Cognición, Electroencefalografía, Agentes neurotransmisores, Personalidad, Pronóstico, Índice de gravedad de la enfermedad, Trastornos relacionados con sustancias, Tratamiento. Resumen: Given the heterogeneous nature of substance abuse, it is notable that several predictors of response are independent of the primary drug of abuse or the treatment setting [208]. Although the strength of the relationship of predictor to outcome varies, the following factors have been identified consistently: severity of dependence or withdrawal;... Link: ./index.php?lvl=notice_display&id=24813

Predictors of response in anxiety disorders / H. Brent Solvason en Psychiatric Clinics of North America, Año 2003 - Vol. 26 No. 2 (Junio)

Público ISBD [artículo]  inPsychiatric Clinics of North America > Año 2003 - Vol. 26 No. 2 (Junio) . - pp. 411-433 Título : Predictors of response in anxiety disorders Tipo de documento: texto impreso Autores: H. Brent Solvason, Autor ; Heidemarie Ernst, Autor ; Walton Roth, Autor Fecha de publicación: 2020 Artículo en la página: pp. 411-433 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastornos de ansiedad, Pronóstico, Drogas psicotrópicas, Índice de gravedad de la enfermedad. Resumen: Anxiety disorder variables such as duration, severity of illness, and comorbidity with other anxiety or mood disorders appear to identify individuals who are at the greatest risk of treatment nonresponse. Conversely, in accord with clinical experience, shorter periods of illness, less severe illness, being treatment naive, and the absence of comorbidity tend to identify patients who are likely to respond robustly to medication management. Link: ./index.php?lvl=notice_display&id=24814 [artículo] Predictors of response in anxiety disorders [texto impreso] / H. Brent Solvason, Autor ; Heidemarie Ernst, Autor ; Walton Roth, Autor . - 2020 . - pp. 411-433. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Psychiatric Clinics of North America > Año 2003 - Vol. 26 No. 2 (Junio) . - pp. 411-433 Palabras clave: Trastornos de ansiedad, Pronóstico, Drogas psicotrópicas, Índice de gravedad de la enfermedad. Resumen: Anxiety disorder variables such as duration, severity of illness, and comorbidity with other anxiety or mood disorders appear to identify individuals who are at the greatest risk of treatment nonresponse. Conversely, in accord with clinical experience, shorter periods of illness, less severe illness, being treatment naive, and the absence of comorbidity tend to identify patients who are likely to respond robustly to medication management. Link: ./index.php?lvl=notice_display&id=24814

Predictors of response to treatment in children and adolescents with mood disorders / Graham J. Emslie en Psychiatric Clinics of North America, Año 2003 - Vol. 26 No. 2 (Junio)

Público ISBD [artículo]  inPsychiatric Clinics of North America > Año 2003 - Vol. 26 No. 2 (Junio) . - pp. 435-456 Título : Predictors of response to treatment in children and adolescents with mood disorders Tipo de documento: texto impreso Autores: Graham J. Emslie, Autor ; Taryn L. Mayes, Autor ; Rebecca S. Laptook, Autor Fecha de publicación: 2020 Artículo en la página: pp. 435-456 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antidepresivos, Biomarcadores, Comorbilidad, Demografía, Familia, Trastornos del estado de ánimo. Resumen: Depression and bipolar disorder are frequently chronic disorders, with onset often beginning in childhood. Mood disorders are becoming more recognized in children and adolescents, and treatment of these disorders has received much attention, particularly in the past 10 years. Link: ./index.php?lvl=notice_display&id=24815 [artículo] Predictors of response to treatment in children and adolescents with mood disorders [texto impreso] / Graham J. Emslie, Autor ; Taryn L. Mayes, Autor ; Rebecca S. Laptook, Autor . - 2020 . - pp. 435-456. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Psychiatric Clinics of North America > Año 2003 - Vol. 26 No. 2 (Junio) . - pp. 435-456 Palabras clave: Antidepresivos, Biomarcadores, Comorbilidad, Demografía, Familia, Trastornos del estado de ánimo. Resumen: Depression and bipolar disorder are frequently chronic disorders, with onset often beginning in childhood. Mood disorders are becoming more recognized in children and adolescents, and treatment of these disorders has received much attention, particularly in the past 10 years. Link: ./index.php?lvl=notice_display&id=24815

Background and rationale for the sequenced treatment alternatives to relieve depression (STAR∗D) study / Maurizio Fava en Psychiatric Clinics of North America, Año 2003 - Vol. 26 No. 2 (Junio)

Público ISBD [artículo]  inPsychiatric Clinics of North America > Año 2003 - Vol. 26 No. 2 (Junio) . - pp. 457-494 Título : Background and rationale for the sequenced treatment alternatives to relieve depression (STAR∗D) study Tipo de documento: texto impreso Autores: Maurizio Fava, Autor ; A. John Rush, Autor ; Madhukar H. Trivedi, Autor Fecha de publicación: 2020 Artículo en la página: pp. 457-494 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antidepresivos, Protocolos clínicos, Ensayos clínicos, Terapia de modalidad combinada, Análisis costo-beneficio, Trastorno depresivo mayor, Escalas de calificación del estado psiquiátrico, Calidad de vida. Resumen: Sequenced Treatment Alternatives to Relieve Depression (STAR*D) attempts to fill in major clinical information gaps and to evaluate the theoretical principles and clinical beliefs that currently guide pharmacotherapy of major depressive disorder. The study is conducted in representative participant groups and settings using clinical management tools that easily can be applied in daily practice. Link: ./index.php?lvl=notice_display&id=24816 [artículo] Background and rationale for the sequenced treatment alternatives to relieve depression (STAR∗D) study [texto impreso] / Maurizio Fava, Autor ; A. John Rush, Autor ; Madhukar H. Trivedi, Autor . - 2020 . - pp. 457-494. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Psychiatric Clinics of North America > Año 2003 - Vol. 26 No. 2 (Junio) . - pp. 457-494 Palabras clave: Antidepresivos, Protocolos clínicos, Ensayos clínicos, Terapia de modalidad combinada, Análisis costo-beneficio, Trastorno depresivo mayor, Escalas de calificación del estado psiquiátrico, Calidad de vida. Resumen: Sequenced Treatment Alternatives to Relieve Depression (STAR*D) attempts to fill in major clinical information gaps and to evaluate the theoretical principles and clinical beliefs that currently guide pharmacotherapy of major depressive disorder. The study is conducted in representative participant groups and settings using clinical management tools that easily can be applied in daily practice. Link: ./index.php?lvl=notice_display&id=24816

Treatment of bipolar depression / Michael E. Thase en Psychiatric Clinics of North America, Año 2003 - Vol. 26 No. 2 (Junio)

Público ISBD [artículo]  inPsychiatric Clinics of North America > Año 2003 - Vol. 26 No. 2 (Junio) . - pp. 495-518 Título : Treatment of bipolar depression : current status, continued challenges, and the STEP-BD approach Tipo de documento: texto impreso Autores: Michael E. Thase, Autor ; Manoj Bhargava, Autor ; Gary S. Sachs, Autor Fecha de publicación: 2020 Artículo en la página: pp. 495-518 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antidepresivos, Agentes antimaníacos, Trastorno bipolar, Drogas psicotrópicas. Resumen: Even though at least 10% (if not 20%) of those who experience a first lifetime episode of depression will subsequently develop bipolar disorder, the alliance of academic and industry research agendas that leads to developing and testing new antidepressants has failed to produce a sufficient knowledge base. Link: ./index.php?lvl=notice_display&id=24817 [artículo] Treatment of bipolar depression : current status, continued challenges, and the STEP-BD approach [texto impreso] / Michael E. Thase, Autor ; Manoj Bhargava, Autor ; Gary S. Sachs, Autor . - 2020 . - pp. 495-518. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Psychiatric Clinics of North America > Año 2003 - Vol. 26 No. 2 (Junio) . - pp. 495-518 Palabras clave: Antidepresivos, Agentes antimaníacos, Trastorno bipolar, Drogas psicotrópicas. Resumen: Even though at least 10% (if not 20%) of those who experience a first lifetime episode of depression will subsequently develop bipolar disorder, the alliance of academic and industry research agendas that leads to developing and testing new antidepressants has failed to produce a sufficient knowledge base. Link: ./index.php?lvl=notice_display&id=24817