Impact of CYP2C19 Genotype on Escitalopram Exposure and Therapeutic Failure / Marin M. Jukic en The American Journal of Psychiatry, Año 2018 - Vol. 175 - No.5 (Mayo)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2018 - Vol. 175 - No.5 (Mayo) . - pp. 463-470 Título : Impact of CYP2C19 Genotype on Escitalopram Exposure and Therapeutic Failure : A Retrospective Study Based on 2,087 Patients. Tipo de documento: texto impreso Autores: Marin M. Jukic, Autor ; Tore Haslemo, Autor ; Espen Molden, Autor Fecha de publicación: 2018 Artículo en la página: pp. 463-470 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antidepresivos, CYP2C19, Escitalopram, Genética, Farmacocinética Resumen: The antidepressant escitalopram is predominantly metabolized by the polymorphic CYP2C19 enzyme. The authors investigated the effect of CYP2C19 genotype on exposure and therapeutic failure of escitalopram in a large patient population. Link: ./index.php?lvl=notice_display&id=17325 [artículo] Impact of CYP2C19 Genotype on Escitalopram Exposure and Therapeutic Failure : A Retrospective Study Based on 2,087 Patients. [texto impreso] / Marin M. Jukic, Autor ; Tore Haslemo, Autor ; Espen Molden, Autor . - 2018 . - pp. 463-470. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2018 - Vol. 175 - No.5 (Mayo) . - pp. 463-470 Palabras clave: Antidepresivos, CYP2C19, Escitalopram, Genética, Farmacocinética Resumen: The antidepressant escitalopram is predominantly metabolized by the polymorphic CYP2C19 enzyme. The authors investigated the effect of CYP2C19 genotype on exposure and therapeutic failure of escitalopram in a large patient population. Link: ./index.php?lvl=notice_display&id=17325

Impact of cyp2d6 genotype on steady state serum concentrations of risperidone and 9 hydroxyrisperidone in patients using long acting injectable risperidone / Magnhild Hendset en Journal of Clinical Psychopharmacology, Año 2009 - Vol. 29 - No. 6 (Diciembre)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2009 - Vol. 29 - No. 6 (Diciembre) . - pp. 537-541 Título : Impact of cyp2d6 genotype on steady state serum concentrations of risperidone and 9 hydroxyrisperidone in patients using long acting injectable risperidone Tipo de documento: texto impreso Autores: Magnhild Hendset, Autor ; Espen Molden, Autor ; Helge Refsum, Autor Fecha de publicación: 2022 Artículo en la página: pp. 537-541 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Risperidona, 9-hidroxirisperidona, CYP2D6, Concentración sérica, Tabletas, Inyección de acción prolongada Resumen: An increased risk of adverse effects and discontinuation of risperidone therapy is observed in patients with impaired cytochrome P450 2D6 (CYP2D6) function on oral risperidone therapy. The present study is the first to investigate the impact of CYP2D6 genotype on serum concentrations of risperidone and 9-hydroxyrisperidone in patients using injectable long-acting risperidone. Link: ./index.php?lvl=notice_display&id=29476 [artículo] Impact of cyp2d6 genotype on steady state serum concentrations of risperidone and 9 hydroxyrisperidone in patients using long acting injectable risperidone [texto impreso] / Magnhild Hendset, Autor ; Espen Molden, Autor ; Helge Refsum, Autor . - 2022 . - pp. 537-541. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2009 - Vol. 29 - No. 6 (Diciembre) . - pp. 537-541 Palabras clave: Risperidona, 9-hidroxirisperidona, CYP2D6, Concentración sérica, Tabletas, Inyección de acción prolongada Resumen: An increased risk of adverse effects and discontinuation of risperidone therapy is observed in patients with impaired cytochrome P450 2D6 (CYP2D6) function on oral risperidone therapy. The present study is the first to investigate the impact of CYP2D6 genotype on serum concentrations of risperidone and 9-hydroxyrisperidone in patients using injectable long-acting risperidone. Link: ./index.php?lvl=notice_display&id=29476

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